Heteroplasmy of mouse mtDNA is genetically unstable and results in altered behavior and cognition MS Sharpley, C Marciniak, K Eckel-Mahan, M McManus, M Crimi, ... Cell 151 (2), 333-343, 2012 | 407 | 2012 |
Nuclear localization of mitochondrial TCA cycle enzymes as a critical step in mammalian zygotic genome activation R Nagaraj, MS Sharpley, F Chi, D Braas, Y Zhou, R Kim, AT Clark, ... Cell 168 (1-2), 210-223. e11, 2017 | 278 | 2017 |
Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers and ubiquinone oxidoreductases AM James, MS Sharpley, ARB Manas, FE Frerman, J Hirst, RAJ Smith, ... Journal of Biological Chemistry 282 (20), 14708-14718, 2007 | 272 | 2007 |
Mouse mtDNA mutant model of Leber hereditary optic neuropathy CS Lin, MS Sharpley, W Fan, KG Waymire, AA Sadun, V Carelli, ... Proceedings of the National Academy of Sciences 109 (49), 20065-20070, 2012 | 237 | 2012 |
Interactions between phospholipids and NADH: ubiquinone oxidoreductase (complex I) from bovine mitochondria MS Sharpley, RJ Shannon, F Draghi, J Hirst Biochemistry 45 (1), 241-248, 2006 | 230 | 2006 |
Extracellular matrix remodeling regulates glucose metabolism through TXNIP destabilization WJ Sullivan, PJ Mullen, EW Schmid, A Flores, M Momcilovic, MS Sharpley, ... Cell 175 (1), 117-132. e21, 2018 | 214 | 2018 |
Mitochondrial DNA variant associated with Leber hereditary optic neuropathy and high-altitude Tibetans F Ji, MS Sharpley, O Derbeneva, LS Alves, P Qian, Y Wang, D Chalkia, ... Proceedings of the National Academy of Sciences 109 (19), 7391-7396, 2012 | 154 | 2012 |
Glycolysis-independent glucose metabolism distinguishes TE from ICM fate during mammalian embryogenesis F Chi, MS Sharpley, R Nagaraj, SS Roy, U Banerjee Developmental cell 53 (1), 9-26. e4, 2020 | 129 | 2020 |
Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH: ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species MS King, MS Sharpley, J Hirst Biochemistry 48 (9), 2053-2062, 2009 | 118 | 2009 |
The inhibition of mitochondrial complex I (NADH: ubiquinone oxidoreductase) by Zn2+ MS Sharpley, J Hirst Journal of Biological Chemistry 281 (46), 34803-34809, 2006 | 94 | 2006 |
Metabolic plasticity drives development during mammalian embryogenesis MS Sharpley, F Chi, J Ten Hoeve, U Banerjee Developmental Cell 56 (16), 2329-2347. e6, 2021 | 41 | 2021 |
Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis JR Girard, LM Goins, DM Vuu, MS Sharpley, CM Spratford, SR Mantri, ... Elife 10, 2021 | 32 | 2021 |
Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair S Li, T Yokota, P Wang, J Ten Hoeve, F Ma, TM Le, ER Abt, Y Zhou, R Wu, ... The Journal of clinical investigation 132 (2), 2022 | 24 | 2022 |
The Metabolic Landscape of Thymic T Cell Development In Vivo and In Vitro V Sun, M Sharpley, KE Kaczor-Urbanowicz, P Chang, A Montel-Hagen, ... Frontiers in Immunology, 2993, 2021 | 24 | 2021 |