Vaccine instability in the cold chain: mechanisms, analysis and formulation strategies OS Kumru, SB Joshi, DE Smith, CR Middaugh, T Prusik, DB Volkin Biologicals 42 (5), 237-259, 2014 | 425 | 2014 |
Structural characterization of IgG1 mAb aggregates and particles generated under various stress conditions SN Telikepalli, OS Kumru, C Kalonia, R Esfandiary, SB Joshi, ... Journal of pharmaceutical sciences 103 (3), 796-809, 2014 | 127 | 2014 |
Compatibility, physical stability, and characterization of an IgG4 monoclonal antibody after dilution into different intravenous administration bags OS Kumru, J Liu, JA Ji, W Cheng, YJ Wang, T Wang, SB Joshi, ... Journal of pharmaceutical sciences 101 (10), 3636-3650, 2012 | 104 | 2012 |
Formulation and stabilization of recombinant protein based virus-like particle vaccines NK Jain, N Sahni, OS Kumru, SB Joshi, DB Volkin, CR Middaugh Advanced drug delivery reviews 93, 42-55, 2015 | 102 | 2015 |
Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice NC Dalvie, SA Rodriguez-Aponte, BL Hartwell, LH Tostanoski, ... Proceedings of the National Academy of Sciences 118 (38), e2106845118, 2021 | 77 | 2021 |
Effect of ionic strength and pH on the physical and chemical stability of a monoclonal antibody antigen-binding fragment T Wang, OS Kumru, L Yi, YJ Wang, J Zhang, JH Kim, SB Joshi, ... Journal of pharmaceutical sciences 102 (8), 2520-2537, 2013 | 73 | 2013 |
Characterization of the physical stability of a lyophilized IgG1 mAb after accelerated shipping-like stress S Telikepalli, OS Kumru, JH Kim, SB Joshi, KB O'berry, AW Blake-Haskins, ... Journal of pharmaceutical sciences 104 (2), 495-507, 2015 | 59 | 2015 |
Translocation of Borrelia burgdorferi surface lipoprotein OspA through the outer membrane requires an unfolded conformation and can initiate at the C‐terminus RJ Schulze, S Chen, OS Kumru, WR Zückert Molecular microbiology 76 (5), 1266-1278, 2010 | 55 | 2010 |
Calculating the mass of subvisible protein particles with improved accuracy using microflow imaging data C Kalonia, OS Kumru, VI Prajapati, R Mathaes, J Engert, S Zhou, ... Journal of pharmaceutical sciences 104 (2), 536-547, 2015 | 51 | 2015 |
A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates PAB Weidenbacher, M Sanyal, N Friedland, S Tang, PS Arunachalam, ... Nature Communications 14 (1), 2149, 2023 | 45 | 2023 |
Radar chart array analysis to visualize effects of formulation variables on IgG1 particle formation as measured by multiple analytical techniques C Kalonia, OS Kumru, JH Kim, CR Middaugh, DB Volkin Journal of pharmaceutical sciences 102 (12), 4256-4267, 2013 | 42 | 2013 |
Surface localization determinants of Borrelia OspC/Vsp family lipoproteins OS Kumru, RJ Schulze, MV Rodnin, AS Ladokhin, WR Zückert Journal of bacteriology 193 (11), 2814-2825, 2011 | 41 | 2011 |
Physical characterization and stabilization of a lentiviral vector against adsorption and freeze-thaw OS Kumru, Y Wang, CWR Gombotz, B Kelley-Clarke, W Cieplak, T Kim, ... Journal of Pharmaceutical Sciences 107 (11), 2764-2774, 2018 | 39 | 2018 |
Specificity and role of the Borrelia burgdorferi CtpA protease in outer membrane protein processing OS Kumru, I Bunikis, I Sorokina, S Bergström, WR Zückert Journal of bacteriology 193 (20), 5759-5765, 2011 | 33 | 2011 |
SARS-CoV-2 receptor binding domain displayed on HBsAg virus–like particles elicits protective immunity in macaques NC Dalvie, LH Tostanoski, SA Rodriguez-Aponte, K Kaur, S Bajoria, ... Science advances 8 (11), eabl6015, 2022 | 29 | 2022 |
Preformulation characterization and stability assessments of secretory IgA monoclonal antibodies as potential candidates for passive immunization by oral administration Y Hu, OS Kumru, J Xiong, LR Antunez, J Hickey, Y Wang, L Cavacini, ... Journal of Pharmaceutical Sciences 109 (1), 407-421, 2020 | 27 | 2020 |
Combined semi-empirical screening and design of experiments (DOE) approach to identify candidate formulations of a lyophilized live attenuated tetravalent viral vaccine candidate A Patel, SM Erb, L Strange, RS Shukla, OS Kumru, L Smith, P Nelson, ... Vaccine 36 (22), 3169-3179, 2018 | 27 | 2018 |
Investigation of a monoclonal antibody against enterotoxigenic Escherichia coli, expressed as secretory IgA1 and IgA2 in plants AYH Teh, L Cavacini, Y Hu, OS Kumru, J Xiong, DT Bolick, SB Joshi, ... Gut microbes 13 (1), 1859813, 2021 | 22 | 2021 |
Evolution and design of protein structure by folding nucleus symmetric expansion LM Longo, OS Kumru, CR Middaugh, M Blaber Structure 22 (10), 1377-1384, 2014 | 22 | 2014 |
Probing structurally altered and aggregated states of therapeutically relevant proteins using G roEL coupled to bio‐layer interferometry S Naik, OS Kumru, M Cullom, SN Telikepalli, E Lindboe, TL Roop, ... Protein Science 23 (10), 1461-1478, 2014 | 21 | 2014 |