Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2593 | 2019 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 988 | 2017 |
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function G Davies, M Lam, SE Harris, JW Trampush, M Luciano, WD Hill, ... Nature communications 9 (1), 2098, 2018 | 722 | 2018 |
Genetic architecture of subcortical brain structures in 38,851 individuals CL Satizabal, HHH Adams, DP Hibar, CC White, MJ Knol, JL Stein, ... Nature genetics 51 (11), 1624-1636, 2019 | 284 | 2019 |
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation A Teumer, L Chaker, S Groeneweg, Y Li, C Di Munno, C Barbieri, ... Nature communications 9 (1), 4455, 2018 | 260 | 2018 |
Association of branched‐chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: a prospective study in eight cohorts J Tynkkynen, V Chouraki, SJ van der Lee, J Hernesniemi, Q Yang, S Li, ... Alzheimer's & Dementia 14 (6), 723-733, 2018 | 235 | 2018 |
Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies SJ van der Lee, CE Teunissen, R Pool, MJ Shipley, A Teumer, V Chouraki, ... Alzheimer's & Dementia 14 (6), 707-722, 2018 | 201 | 2018 |
Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study V Chouraki, SR Preis, Q Yang, A Beiser, S Li, MG Larson, G Weinstein, ... Alzheimer's & Dementia 13 (12), 1327-1336, 2017 | 107 | 2017 |
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults E Hofer, GV Roshchupkin, HHH Adams, MJ Knol, H Lin, S Li, H Zare, ... Nature communications 11 (1), 4796, 2020 | 97 | 2020 |
Common genetic variation indicates separate causes for periventricular and deep white matter hyperintensities NJ Armstrong, KA Mather, M Sargurupremraj, MJ Knol, R Malik, ... Stroke 51 (7), 2111-2121, 2020 | 94 | 2020 |
Meta-analysis of epigenome-wide association studies of cognitive abilities RE Marioni, AF McRae, J Bressler, E Colicino, E Hannon, S Li, D Prada, ... Molecular psychiatry 23 (11), 2133-2144, 2018 | 86 | 2018 |
The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE) FJ Wolters, Q Yang, ML Biggs, J Jakobsdottir, S Li, DS Evans, JC Bis, ... PLoS One 14 (7), e0219668, 2019 | 70 | 2019 |
Association of common genetic variants with brain microbleeds: a genome-wide association study MJ Knol, D Lu, M Traylor, HHH Adams, JRJ Romero, AV Smith, ... Neurology 95 (24), e3331-e3343, 2020 | 69 | 2020 |
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease MG Duperron, MJ Knol, Q Le Grand, TE Evans, A Mishra, A Tsuchida, ... Nature medicine 29 (4), 950-962, 2023 | 58 | 2023 |
Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects A Mishra, G Chauhan, MH Violleau, D Vojinovic, X Jian, JC Bis, S Li, ... Brain 142 (4), 1009-1023, 2019 | 52 | 2019 |
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume D Vojinovic, HH Adams, X Jian, Q Yang, AV Smith, JC Bis, A Teumer, ... Nature communications 9 (1), 3945, 2018 | 47 | 2018 |
Association of circulating metabolites in plasma or serum and risk of stroke: meta-analysis from 7 prospective cohorts D Vojinovic, M Kalaoja, S Trompet, K Fischer, MJ Shipley, S Li, ... Neurology 96 (8), e1110-e1123, 2021 | 39 | 2021 |
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes SJ van Der Lee, MJ Knol, G Chauhan, CL Satizabal, AV Smith, E Hofer, ... Communications biology 2 (1), 285, 2019 | 33 | 2019 |
Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI Y Yang, MJ Knol, R Wang, A Mishra, D Liu, M Luciano, A Teumer, ... Brain 146 (2), 492-506, 2023 | 27 | 2023 |
Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome‐wide association study in over 12,000 non‐demented … V Damotte, SJ van Der Lee, V Chouraki, B Grenier‐Boley, J Simino, ... Alzheimer's & Dementia 17 (10), 1663-1674, 2021 | 27 | 2021 |