Efficient precise in vivo base editing in adult dystrophic mice L Xu, C Zhang, H Li, P Wang, Y Gao, NA Mokadam, J Ma, WD Arnold, ... Nature communications 12 (1), 3719, 2021 | 89 | 2021 |
Life-long AAV-mediated CRISPR genome editing in dystrophic heart improves cardiomyopathy without causing serious lesions in mdx mice L Xu, YS Lau, Y Gao, H Li, R Han Molecular Therapy 27 (8), 1407-1414, 2019 | 51 | 2019 |
Genetic recovery of ErbB4 in adulthood partially restores brain functions in null mice H Wang, F Liu, W Chen, X Sun, W Cui, Z Dong, K Zhao, H Zhang, H Li, ... Proceedings of the National Academy of Sciences 115 (51), 13105-13110, 2018 | 42 | 2018 |
An open-source video tracking system for mouse locomotor activity analysis C Zhang, H Li, R Han BMC Research Notes 13, 1-6, 2020 | 34 | 2020 |
Controlling of glutamate release by neuregulin3 via inhibiting the assembly of the SNARE complex YN Wang, D Figueiredo, XD Sun, ZQ Dong, WB Chen, WP Cui, F Liu, ... Proceedings of the National Academy of Sciences 115 (10), 2508-2513, 2018 | 34 | 2018 |
Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth H Li, L Zhao, YS Lau, C Zhang, R Han Oncogene 40 (1), 177-188, 2021 | 32 | 2021 |
Itch promotes the neddylation of JunB and regulates JunB-dependent transcription H Li, H Zhu, Y Liu, F He, P Xie, L Zhang Cellular signalling 28 (9), 1186-1195, 2016 | 32 | 2016 |
Neddylation is critical to cortical development by regulating Wnt/β-catenin signaling L Zhang, H Jing, H Li, W Chen, B Luo, H Zhang, Z Dong, L Li, H Su, ... Proceedings of the National Academy of Sciences 117 (42), 26448-26459, 2020 | 25 | 2020 |
Neddylation stabilizes Nav1.1 to maintain interneuron excitability and prevent seizures in murine epilepsy models W Chen, B Luo, N Gao, H Li, H Wang, L Li, W Cui, L Zhang, D Sun, F Liu, ... The Journal of clinical investigation 131 (8), 2021 | 24 | 2021 |
Correction of DMD in human iPSC-derived cardiomyocytes by base-editing-induced exon skipping P Wang, H Li, M Zhu, RY Han, S Guo, R Han Molecular Therapy Methods & Clinical Development 28, 40-50, 2023 | 16 | 2023 |
VCP/p97 increases BMP signaling by accelerating ubiquitin ligase Smurf1 degradation H Li, Y Cui, J Wei, C Liu, Y Chen, CP Cui, L Li, X Zhang, L Zhang The FASEB Journal 33 (2), 2928-2943, 2019 | 14 | 2019 |
Liver-specific in vivo base editing of Angptl3 via AAV delivery efficiently lowers blood lipid levels in mice Y Zuo, C Zhang, Y Zhou, H Li, W Xiao, RW Herzog, J Xu, J Zhang, ... Cell & Bioscience 13 (1), 109, 2023 | 11 | 2023 |
Genetic disruption of the inflammasome adaptor ASC has minimal impact on the pathogenesis of Duchenne muscular dystrophy in mdx mice YS Lau, L Zhao, C Zhang, H Li, R Han Life sciences 257, 118069, 2020 | 9 | 2020 |
BVES is a novel interactor of ANO5 and regulates myoblast differentiation H Li, L Xu, Y Gao, Y Zuo, Z Yang, L Zhao, Z Chen, S Guo, R Han Cell & Bioscience 11, 1-10, 2021 | 8 | 2021 |
Systemic AAV9. BVES delivery ameliorates muscular dystrophy in a mouse model of LGMDR25 H Li, P Wang, E Hsu, KM Pinckard, KI Stanford, R Han Molecular Therapy 31 (2), 398-408, 2023 | 5 | 2023 |
Defective BVES-mediated feedback control of cAMP in muscular dystrophy H Li, P Wang, C Zhang, Y Zuo, Y Zhou, R Han Nature communications 14 (1), 1785, 2023 | 3 | 2023 |
Autophagy in striated muscle diseases H Li, L Zhang, L Zhang, R Han Frontiers in Cardiovascular Medicine 9, 1000067, 2022 | 1 | 2022 |