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Kevin Ming-Chin Lee
Kevin Ming-Chin Lee
在 unimelb.edu.au 的电子邮件经过验证 - 首页
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Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
MA Dawson, RK Prinjha, A Dittmann, G Giotopoulos, M Bantscheff, ...
Nature 478 (7370), 529-533, 2011
17092011
Suppression of inflammation by a synthetic histone mimic
E Nicodeme, KL Jeffrey, U Schaefer, S Beinke, S Dewell, C Chung, ...
Nature 468 (7327), 1119-1123, 2010
16862010
Epigenetic protein families: a new frontier for drug discovery
CH Arrowsmith, C Bountra, PV Fish, K Lee, M Schapira
Nature reviews Drug discovery 11 (5), 384-400, 2012
15682012
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
L Kruidenier, C Chung, Z Cheng, J Liddle, KH Che, G Joberty, ...
Nature 488 (7411), 404-408, 2012
9612012
Orexigen-sensitive NPY/AgRP pacemaker neurons in the hypothalamic arcuate nucleus
M van den Top, K Lee, AD Whyment, AM Blanks, D Spanswick
Nature neuroscience 7 (5), 493-494, 2004
4972004
Discovery and characterization of small molecule inhibitors of the BET family bromodomains
C Chung, H Coste, JH White, O Mirguet, J Wilde, RL Gosmini, C Delves, ...
Journal of medicinal chemistry 54 (11), 3827-3838, 2011
4272011
β3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics
K Morgan, EB Stevens, B Shah, PJ Cox, AK Dixon, K Lee, RD Pinnock, ...
Proceedings of the National Academy of Sciences 97 (5), 2308-2313, 2000
4162000
Suppression of the antiviral response by an influenza histone mimic
I Marazzi, JSY Ho, J Kim, B Manicassamy, S Dewell, RA Albrecht, ...
Nature 483 (7390), 428-433, 2012
3282012
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling
D Levy, AJ Kuo, Y Chang, U Schaefer, C Kitson, P Cheung, A Espejo, ...
Nature immunology 12 (1), 29, 2011
2902011
Place your BETs: the therapeutic potential of bromodomains
RK Prinjha, J Witherington, K Lee
Trends in pharmacological sciences 33 (3), 146-153, 2012
2752012
Gabapentin inhibits high‐threshold calcium channel currents in cultured rat dorsal root ganglion neurones
KG Sutton, DJ Martin, RD Pinnock, K Lee, RH Scott
British journal of pharmacology 135 (1), 257-265, 2002
2662002
Identification of a novel series of BET family bromodomain inhibitors: binding mode and profile of I-BET151 (GSK1210151A)
J Seal, Y Lamotte, F Donche, A Bouillot, O Mirguet, F Gellibert, ...
Bioorganic & medicinal chemistry letters 22 (8), 2968-2972, 2012
2462012
Subunit positional effects revealed by novel heteromeric inwardly rectifying K+ channels.
M Pessia, SJ Tucker, K Lee, CT Bond, JP Adelman
The EMBO journal 15 (12), 2980-2987, 1996
2341996
An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses
M Mann, A Mehta, JL Zhao, K Lee, GK Marinov, Y Garcia-Flores, LF Lu, ...
Nature communications 8 (1), 851, 2017
2252017
Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors
HS Bandukwala, J Gagnon, S Togher, JA Greenbaum, ED Lamperti, ...
Proceedings of the National Academy of Sciences 109 (36), 14532-14537, 2012
2232012
GM-CSF-based treatments in COVID-19: reconciling opposing therapeutic approaches
FM Lang, KMC Lee, JR Teijaro, B Becher, JA Hamilton
Nature Reviews Immunology 20 (8), 507-514, 2020
2132020
Calcium signaling and T-type calcium channels in cancer cell cycling
JT Taylor, XB Zeng, JE Pottle, K Lee, AR Wang, GY Stephenie, ...
World journal of gastroenterology: WJG 14 (32), 4984, 2008
1902008
Cellular and molecular action of the putative GABA-mimetic, gabapentin
YP Maneuf, MI Gonzalez, KS Sutton, FZ Chung, RD Pinnock, K Lee
Cellular and Molecular Life Sciences CMLS 60, 742-750, 2003
1842003
Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response
TC Fang, U Schaefer, I Mecklenbrauker, A Stienen, S Dewell, MS Chen, ...
Journal of Experimental Medicine 209 (4), 661-669, 2012
1782012
Gabapentin-mediated inhibition of voltage-activated Ca2+ channel currents in cultured sensory neurones is dependent on culture conditions and channel subunit expression
DJ Martin, D McClelland, MB Herd, KG Sutton, MD Hall, K Lee, ...
Neuropharmacology 42 (3), 353-366, 2002
1682002
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