| Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer UN Wasko, J Jiang, TC Dalton, A Curiel-Garcia, AC Edwards, Y Wang, ... Nature, 1-3, 2024 | 51 | 2024 |
| Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators A Obradovic, C Ager, M Turunen, T Nirschl, M Khosravi-Maharlooei, ... Cancer Cell 41 (5), 933-949. e11, 2023 | 27 | 2023 |
| Pancreatic ductal adenocarcinoma comprises coexisting regulatory states with both common and distinct dependencies P Laise, M Turunen, HC Maurer, AG Curiel, E Elyada, B Schmierer, ... Biorxiv, preprint, 2020 | 16 | 2020 |
| Robust Calibration of High Dimension Nonlinear Dynamical Models for Omics Data: An Application in Cancer Systems Biology F Bianconi, C Antonini, L Tomassoni, P Valigi IEEE Transactions on Control Systems Technology 28 (1), 196-207, 2018 | 12 | 2018 |
| Application of conditional robust calibration to ordinary differential equations models in computational systems biology: A comparison of two sampling strategies F Bianconi, C Antonini, L Tomassoni, P Valigi IET Systems Biology 14 (3), 107-119, 2020 | 11 | 2020 |
| CRA toolbox: software package for conditional robustness analysis of cancer systems biology models in MATLAB F Bianconi, C Antonini, L Tomassoni, P Valigi BMC bioinformatics 20, 1-19, 2019 | 10 | 2019 |
| Tumor explants elucidate a Cascade of Paracrine SHH, WNT, and VEGF signals driving pancreatic Cancer Angiosuppression MC Hasselluhn, AR Decker-Farrell, L Vlahos, DH Thomas, ... Cancer discovery 14 (2), 348-361, 2024 | 9 | 2024 |
| A new Bayesian methodology for nonlinear model calibration in Computational Systems Biology F Bianconi, L Tomassoni, C Antonini, P Valigi Frontiers in Applied Mathematics and Statistics 6, 25, 2020 | 8 | 2020 |
| Reverse phase protein array (RPPA) combined with computational analysis to unravel relevant prognostic factors in non-small cell lung cancer (NSCLC): a pilot study V Ludovini, R Chiari, L Tomassoni, C Antonini, E Baldelli, S Baglivo, ... Oncotarget 8 (47), 83343, 2017 | 5 | 2017 |
| Adult enteric Dclk1-positive glial and neuronal cells reveal distinct responses to acute intestinal injury M Middelhoff, G Valenti, L Tomassoni, Y Ochiai, B Belin, R Takahashi, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 322 (6 …, 2022 | 4 | 2022 |
| Developmental and MAPK-responsive transcription factors drive distinct malignant subtypes and genetic dependencies in pancreatic cancer P Laise, M Turunen, AC Garcia, L Tomassoni, HC Maurer, E Elyada, ... bioRxiv, 2020.10. 27.357269, 2020 | 3 | 2020 |
| Conditional robust calibration (crc): a new computational Bayesian methodology for model parameters estimation and identifiability analysis F Bianconi, C Antonini, L Tomassoni, P Valigi bioRxiv, 197400, 2017 | 3 | 2017 |
| Case Study of Single-cell Protein Activity Based Drug Prediction for Precision Treatment of Cholangiocarcinoma A Obradovic, L Tomassoni, D Yu, K Guillan, K Souto, E Fraser, S Bates, ... bioRxiv, 2022.02. 28.482410, 2022 | 2 | 2022 |
| An Application of Conditional Robust Calibration (CRC) to The Lotka-Volterra Predator-Prey model in computational systems biology: a comparison of two sampling strategies F Bianconi, C Antonini, L Tomassoni, P Valigi IEEE ENGINEERING IN MEDICINE AND BIOLOGY... ANNUAL CONFERENCE PROCEEDINGS …, 2018 | 1 | 2018 |
| Identification and Targeting of Regulators of SARS-CoV-2-Host Interactions in the Airway Epithelium B Dirvin, H Noh, L Tomassoni, D Cao, Y Zhou, X Ke, J Qian, S Jangra, ... bioRxiv, 2024 | | 2024 |
| Targeted delivery of napabucasin with radiotherapy improves outcomes in diffuse midline glioma M Gallitto, X Zhang, G De Los Santos, HJ Wei, EC Fernández, S Duan, ... Neuro-Oncology, noae215, 2024 | | 2024 |
| Abstract C023: PDAC tumors from patients treated with combination MEK and autophagy inhibition reveal a treatment sensitive epithelial subtype that is enriched in murine models BW Labadie, AZ Obradovic, SS Ana, M May, N Sender, IV Ross, ... Cancer Research 84 (17_Supplement_2), C023-C023, 2024 | | 2024 |
| Discovery and validation of effective combination therapies targeting cell state-specific master regulator vulnerabilities by network-based protein activity inference in … EC Fernandez, L Tomassoni, X Zhang, A Obradovic, P Laise, AT Griffin, ... Cancer Research 84 (6_Supplement), 5460-5460, 2024 | | 2024 |
| Adaptive heterogeneity enables the survival of residual malignant PDAC cells in response to RAS-GTP inhibition L Tomassoni, UN Wasko, AC Garcia, TC Dalton, P Laise, SA Sastra, ... Cancer Research 84 (6_Supplement), 3874-3874, 2024 | | 2024 |
| RAS-GTP inhibition modulates Hedgehog signaling, suppressing myCAFs and promoting iCAFs in pancreatic ductal adenocarcinoma M Hasselluhn, L Tomassoni, U Wasko, A Curiel-Garcia, T Dalton, ... Cancer Research 84 (6_Supplement), 1578-1578, 2024 | | 2024 |
