| Prodrugs of phosphonates and phosphates: crossing the membrane barrier AJ Wiemer, DF Wiemer Phosphorus Chemistry I: Asymmetric Synthesis and Bioactive Compounds, 115-160, 2015 | 195 | 2015 |
| Synthesis of a phosphoantigen prodrug that potently activates Vγ9Vδ2 T-lymphocytes CHC Hsiao, X Lin, RJ Barney, RR Shippy, J Li, O Vinogradova, ... Chemistry & biology 21 (8), 945-954, 2014 | 114 | 2014 |
| Stepping forward in antibody-drug conjugate development Y Jin, MA Schladetsch, X Huang, MJ Balunas, AJ Wiemer Pharmacology & therapeutics 229, 107917, 2022 | 109 | 2022 |
| Synthesis and biological activity of isoprenoid bisphosphonates LW Shull, AJ Wiemer, RJ Hohl, DF Wiemer Bioorganic & medicinal chemistry 14 (12), 4130-4136, 2006 | 104 | 2006 |
| Digeranyl bisphosphonate inhibits geranylgeranyl pyrophosphate synthase AJ Wiemer, H Tong, KM Swanson, RJ Hohl Biochemical and biophysical research communications 353 (4), 921-925, 2007 | 100 | 2007 |
| The intermediate enzymes of isoprenoid metabolism as anticancer targets AJ Wiemer, RJ Hohl, DF Wiemer Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2009 | 87 | 2009 |
| Contact-dependent T cell activation and T cell stopping require talin1 SA Wernimont, AJ Wiemer, DA Bennin, SJ Monkley, T Ludwig, ... The Journal of Immunology 187 (12), 6256-6267, 2011 | 83 | 2011 |
| Geranylgeranyl diphosphate synthase: an emerging therapeutic target AJ Wiemer, DF Wiemer, RJ Hohl Clinical Pharmacology & Therapeutics 90 (6), 804-812, 2011 | 74 | 2011 |
| Cyclopropene cycloadditions with annulated furans: total synthesis of (+)-and (−)-frondosin B and (+)-frondosin A EZ Oblak, MD VanHeyst, J Li, AJ Wiemer, DL Wright Journal of the American Chemical Society 136 (11), 4309-4315, 2014 | 68 | 2014 |
| Mono-and dialkyl isoprenoid bisphosphonates as geranylgeranyl diphosphate synthase inhibitors AJ Wiemer, SY Jose, KM Lamb, RJ Hohl, DF Wiemer Bioorganic & medicinal chemistry 16 (1), 390-399, 2008 | 64 | 2008 |
| Pivaloyloxymethyl-modified isoprenoid bisphosphonates display enhanced inhibition of cellular geranylgeranylation AJ Wiemer, SY Jose, LW Shull, RJ Barney, BM Wasko, KM Lamb, RJ Hohl, ... Bioorganic & medicinal chemistry 16 (7), 3652-3660, 2008 | 63 | 2008 |
| Inhibition of geranylgeranyl diphosphate synthase induces apoptosis through multiple mechanisms and displays synergy with inhibition of other isoprenoid biosynthetic enzymes A Dudakovic, AJ Wiemer, KM Lamb, LA Vonnahme, SE Dietz, RJ Hohl Journal of Pharmacology and Experimental Therapeutics 324 (3), 1028-1036, 2008 | 58 | 2008 |
| Total synthesis of (R, R, R)-and (S, S, S)-schweinfurthin F: differences of bioactivity in the enantiomeric series NR Mente, AJ Wiemer, JD Neighbors, JA Beutler, RJ Hohl, DF Wiemer Bioorganic & medicinal chemistry letters 17 (4), 911-915, 2007 | 57 | 2007 |
| A live imaging cell motility screen identifies prostaglandin E2 as a T cell stop signal antagonist AJ Wiemer, S Hegde, JE Gumperz, A Huttenlocher The Journal of Immunology 187 (7), 3663-3670, 2011 | 54 | 2011 |
| Metabolic efficacy of phosphate prodrugs and the remdesivir paradigm AJ Wiemer ACS Pharmacology & Translational Science 3 (4), 613-626, 2020 | 53 | 2020 |
| Stereoselective synthesis of the 5 ‘-hydroxy-5 ‘-phosphonate derivatives of cytidine and cytosine arabinoside X Chen, AJ Wiemer, RJ Hohl, DF Wiemer The Journal of Organic Chemistry 67 (26), 9331-9339, 2002 | 53 | 2002 |
| The butyrophilin 3A1 intracellular domain undergoes a conformational change involving the juxtamembrane region K Nguyen, J Li, R Puthenveetil, X Lin, MM Poe, CHC Hsiao, ... The FASEB Journal 31 (11), 4697, 2017 | 52 | 2017 |
| Quantitative determination of farnesyl and geranylgeranyl diphosphate levels in mammalian tissue H Tong, AJ Wiemer, JD Neighbors, RJ Hohl Analytical biochemistry 378 (2), 138-143, 2008 | 50 | 2008 |
| Phosphonamidate prodrugs of a butyrophilin ligand display plasma stability and potent Vγ9 Vδ2 T cell stimulation NA Lentini, BJ Foust, CHC Hsiao, AJ Wiemer, DF Wiemer Journal of medicinal chemistry 61 (19), 8658-8669, 2018 | 46 | 2018 |
| Synthesis and activity of fluorescent isoprenoid pyrophosphate analogues TS Kleckley, AJ Wiemer, SA Holstein, RJ Hohl, DF Wiemer The Journal of organic chemistry 69 (24), 8186-8193, 2004 | 45 | 2004 |
