| Nanofibrillar cellulose hydrogel promotes three-dimensional liver cell culture M Bhattacharya, MM Malinen, P Lauren, YR Lou, SW Kuisma, L Kanninen, ... Journal of controlled release 164 (3), 291-298, 2012 | 488 | 2012 |
| Differentiation of liver progenitor cell line to functional organotypic cultures in 3D nanofibrillar cellulose and hyaluronan-gelatin hydrogels MM Malinen, LK Kanninen, A Corlu, HM Isoniemi, YR Lou, ML Yliperttula, ... Biomaterials 35 (19), 5110-5121, 2014 | 230 | 2014 |
| Modulation of cancer cell survival pathways using multivalent liposomal therapeutic antibody constructs GNC Chiu, LA Edwards, AI Kapanen, MM Malinen, WH Dragowska, ... Molecular cancer therapeutics 6 (3), 844-855, 2007 | 69 | 2007 |
| Organic solute transporter OSTα/β is overexpressed in nonalcoholic steatohepatitis and modulated by drugs associated with liver injury MM Malinen, I Ali, J Bezencon, JJ Beaudoin, KLR Brouwer American Journal of Physiology-Gastrointestinal and Liver Physiology 314 (5 …, 2018 | 54 | 2018 |
| A critical assessment of in vitro tissue models for ADME and drug delivery KS Vellonen, M Malinen, E Mannermaa, A Subrizi, E Toropainen, YR Lou, ... Journal of Controlled Release 190, 94-114, 2014 | 54 | 2014 |
| Novel insights into the organic solute transporter alpha/beta, OSTα/β: From the bench to the bedside JJ Beaudoin, KLR Brouwer, MM Malinen Pharmacology & therapeutics 211, 107542, 2020 | 46 | 2020 |
| Peptide nanofiber hydrogel induces formation of bile canaliculi structures in three-dimensional hepatic cell culture MM Malinen, H Palokangas, M Yliperttula, A Urtti Tissue Engineering Part A 18 (23-24), 2418-2425, 2012 | 39 | 2012 |
| Synthesis and cellular uptake of fluorescently labeled multivalent hyaluronan disaccharide conjugates of oligonucleotide phosphorothioates M Karskela, P Virta, M Malinen, A Urtti, H Lönnberg Bioconjugate chemistry 19 (12), 2549-2558, 2008 | 33 | 2008 |
| Hepatic differentiation of human pluripotent stem cells on human liver progenitor HepaRG-derived acellular matrix LK Kanninen, P Porola, J Niklander, MM Malinen, A Corlu, ... Experimental cell research 341 (2), 207-217, 2016 | 31 | 2016 |
| Regulation of human pluripotent stem cell-derived hepatic cell phenotype by three-dimensional hydrogel models S Toivonen, MM Malinen, J Küblbeck, A Petsalo, A Urtti, P Honkakoski, ... Tissue Engineering Part A 22 (13-14), 971-984, 2016 | 30 | 2016 |
| Pregnancy-related hormones increase nifedipine metabolism in human hepatocytes by inducing CYP3A4 expression R Khatri, N Kulick, RJB Rementer, JK Fallon, C Sykes, AP Schauer, ... Journal of pharmaceutical sciences 110 (1), 412-421, 2021 | 22 | 2021 |
| Protein expression and function of organic anion transporters in short-term and long-term cultures of Huh7 human hepatoma cells MM Malinen, K Ito, HE Kang, P Honkakoski, KLR Brouwer European Journal of Pharmaceutical Sciences 130, 186-195, 2019 | 16 | 2019 |
| Novel in vitro method reveals drugs that inhibit organic solute transporter alpha/beta (OSTα/β) MM Malinen, A Kauttonen, JJ Beaudoin, N Sjöstedt, P Honkakoski, ... Molecular pharmaceutics 16 (1), 238-246, 2018 | 16 | 2018 |
| Multicellular dosimetric chain for molecular radiotherapy exemplified with dose simulations on 3D cell spheroids V Reijonen, LK Kanninen, E Hippeläinen, YR Lou, E Salli, A Sofiev, ... Physica Medica 40, 72-78, 2017 | 12 | 2017 |
| Optimization of canalicular ABC transporter function in HuH-7 cells by modification of culture conditions HE Kang, MM Malinen, C Saran, P Honkakoski, KLR Brouwer Drug Metabolism and Disposition 47 (10), 1222-1230, 2019 | 9 | 2019 |
| Breath figure templated semifluorinated block copolymers with tunable surface properties and binding capabilities L Valtola, M Karesoja, H Tenhu, P Ihalainen, J Sarfraz, J Peltonen, ... Journal of Applied Polymer Science 132 (1), 2015 | 8 | 2015 |
| The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality W Kiander, KS Vellonen, MM Malinen, M Gynther, M Hagström, ... Pharmaceutical Research 38, 1663-1675, 2021 | 6 | 2021 |
| Hepatic transporter alterations by nuclear receptor agonist T0901317 in sandwich-cultured human hepatocytes: proteomic analysis and PBPK modeling to evaluate drug-drug … K Ito, N Sjöstedt, MM Malinen, C Guo, KLR Brouwer Journal of Pharmacology and Experimental Therapeutics 373 (2), 261-268, 2020 | 2 | 2020 |
| Identification of Key Amino Acids that Impact Organic Solute Transporter α/β (OSTα/β) WA Murphy, JJ Beaudoin, T Laitinen, N Sjöstedt, MM Malinen, H Ho, ... Molecular Pharmacology 100 (6), 599-608, 2021 | | 2021 |
| Plant-derived nanofibrillar cellulose hydrogel for cell culture and chemical testing M Yliperttula, A Urtti, YR Lou, M Malinen, P Laurén, L Kanninen, ... US Patent App. 17/190,351, 2021 | | 2021 |
