Soluble TREM2 induces inflammatory responses and enhances microglial survival L Zhong, XF Chen, T Wang, Z Wang, C Liao, Z Wang, R Huang, D Wang, ... Journal of Experimental Medicine 214 (3), 597-607, 2017 | 300 | 2017 |
TREM2 promotes microglial survival by activating Wnt/β-catenin pathway H Zheng, L Jia, CC Liu, Z Rong, L Zhong, L Yang, XF Chen, JD Fryer, ... Journal of Neuroscience 37 (7), 1772-1784, 2017 | 293 | 2017 |
Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer’s disease model L Zhong, Y Xu, R Zhuo, T Wang, K Wang, R Huang, D Wang, Y Gao, ... Nature communications 10 (1), 1365, 2019 | 263 | 2019 |
Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2) L Zhong, Z Wang, D Wang, Z Wang, YA Martens, L Wu, Y Xu, K Wang, J Li, ... Molecular neurodegeneration 13, 1-12, 2018 | 160 | 2018 |
DAP12 stabilizes the C-terminal fragment of the triggering receptor expressed on myeloid cells-2 (TREM2) and protects against LPS-induced pro-inflammatory response L Zhong, XF Chen, ZL Zhang, Z Wang, XZ Shi, K Xu, YW Zhang, H Xu, ... Journal of Biological Chemistry 290 (25), 15866-15877, 2015 | 140 | 2015 |
A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism L Zhong, YZ Xie, TT Cao, Z Wang, T Wang, X Li, RC Shen, H Xu, G Bu, ... Molecular neurodegeneration 11, 1-8, 2016 | 87 | 2016 |
TREM2/DAP12 complex regulates inflammatory responses in microglia via the JNK signaling pathway L Zhong, ZL Zhang, X Li, C Liao, P Mou, T Wang, Z Wang, Z Wang, M Wei, ... Frontiers in Aging Neuroscience 9, 204, 2017 | 77 | 2017 |
Quercetin stabilizes apolipoprotein E and reduces brain Aβ levels in amyloid model mice X Zhang, J Hu, L Zhong, N Wang, L Yang, CC Liu, H Li, X Wang, Y Zhou, ... Neuropharmacology 108, 179-192, 2016 | 67 | 2016 |
Apolipoprotein E epsilon 2 allele and low serum cholesterol as risk factors for gastric cancer in a Chinese Han population R Kang, P Li, T Wang, X Li, Z Wei, Z Zhang, L Zhong, L Cao, ... Scientific reports 6 (1), 19930, 2016 | 50 | 2016 |
The emerging roles and therapeutic potential of soluble TREM2 in Alzheimer’s disease L Zhong, XF Chen Frontiers in aging neuroscience 11, 328, 2019 | 45 | 2019 |
Role of FOXO3 activated by HIV-1 Tat in HIV-associated neurocognitive disorder neuronal apoptosis H Dong, X Ye, L Zhong, J Xu, J Qiu, J Wang, Y Shao, H Xing Frontiers in Neuroscience 13, 44, 2019 | 32 | 2019 |
TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration L Zhong, X Sheng, W Wang, Y Li, R Zhuo, K Wang, L Zhang, DD Hu, ... Immunity 56 (8), 1794-1808. e8, 2023 | 30 | 2023 |
Activation of FAK/Rac1/Cdc42‐GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 … Z Rong, B Cheng, L Zhong, X Ye, X Li, L Jia, Y Li, F Shue, N Wang, ... The FASEB Journal 34 (8), 10984-10997, 2020 | 29 | 2020 |
TMEM59 interacts with TREM2 and modulates TREM2-dependent microglial activities Z Liu, J Ning, X Zheng, J Meng, L Han, H Zheng, L Zhong, XF Chen, ... Cell Death & Disease 11 (8), 678, 2020 | 25 | 2020 |
HIV-1 Tat increases BAG3 via NF-κB signaling to induce autophagy during HIV-associated neurocognitive disorder X Wu, H Dong, X Ye, L Zhong, T Cao, Q Xu, J Wang, Y Zhang, J Xu, ... Cell Cycle 17 (13), 1614-1623, 2018 | 24 | 2018 |
TREMs in Alzheimer's disease: Genetic and clinical investigations J Cheng, XF Guo, T Zhang, L Zhong, GJ Bu, XF Chen Clinica chimica acta 463, 88-95, 2016 | 24 | 2016 |
Association study of TREM2 polymorphism rs75932628 with leucoaraiosis or Parkinson's disease in the Han Chinese population Z Li, L Zhong, L Gu, W Huang, X Shi, X Zhang, X An, Q Lin, CM Tzeng BMJ open 6 (1), e009499, 2016 | 13 | 2016 |
Identification of the minimal active soluble TREM2 sequence for modulating microglial phenotypes and amyloid pathology X Sheng, Y Yao, R Huang, Y Xu, Y Zhu, L Chen, L Zhang, W Wang, ... Journal of Neuroinflammation 18, 1-12, 2021 | 9 | 2021 |
Microglial repopulation reverses cognitive and synaptic deficits in an Alzheimer’s disease model by restoring BDNF signaling W Wang, Y Li, F Ma, X Sheng, K Chen, R Zhuo, C Wang, H Zheng, ... Brain, Behavior, and Immunity 113, 275-288, 2023 | 6 | 2023 |
Enhanced diabetes susceptibility in community dwelling Han elders carrying the Apolipoprotein E 3/3 genotype C Ban, L Zhong, T Wang, M Zhu, J Wang, Z Zhang, Z Wang, N Su, Y Liu, ... PLoS One 11 (3), e0151336, 2016 | 6 | 2016 |