A novel pathway of HMGB1‐mediated inflammatory cell recruitment that requires Mac‐1‐integrin VV Orlova, EY Choi, C Xie, E Chavakis, A Bierhaus, E Ihanus, ... The EMBO journal 26 (4), 1129-1139, 2007 | 495 | 2007 |
Human-iPSC-derived cardiac stromal cells enhance maturation in 3D cardiac microtissues and reveal non-cardiomyocyte contributions to heart disease E Giacomelli, V Meraviglia, G Campostrini, A Cochrane, X Cao, ... Cell stem cell 26 (6), 862-879. e11, 2020 | 425 | 2020 |
Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells VV Orlova, FE Van Den Hil, S Petrus-Reurer, Y Drabsch, P Ten Dijke, ... Nature protocols 9 (6), 1514-1531, 2014 | 373 | 2014 |
Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells E Giacomelli, M Bellin, L Sala, BJ Van Meer, LGJ Tertoolen, VV Orlova, ... Development 144 (6), 1008-1017, 2017 | 301 | 2017 |
MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo L Sala, BJ Van Meer, LGJ Tertoolen, J Bakkers, M Bellin, RP Davis, ... Circulation research 122 (3), e5-e16, 2018 | 289 | 2018 |
The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31) UJH Sachs, CL Andrei-Selmer, A Maniar, T Weiss, C Paddock, VV Orlova, ... Journal of Biological Chemistry 282 (32), 23603-23612, 2007 | 266 | 2007 |
Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts VV Orlova, Y Drabsch, C Freund, S Petrus-Reurer, FE van den Hil, ... Arteriosclerosis, thrombosis, and vascular biology 34 (1), 177-186, 2014 | 242 | 2014 |
Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells MJ Birket, MC Ribeiro, AO Verkerk, D Ward, AR Leitoguinho, ... Nature biotechnology 33 (9), 970-979, 2015 | 240 | 2015 |
Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress C Brocker, N Lassen, T Estey, A Pappa, M Cantore, VV Orlova, ... Journal of Biological Chemistry 285 (24), 18452-18463, 2010 | 216 | 2010 |
Junctional adhesion molecule-C regulates vascular endothelial permeability by modulating VE-cadherin–mediated cell–cell contacts VV Orlova, M Economopoulou, F Lupu, S Santoso, T Chavakis The Journal of experimental medicine 203 (12), 2703-2714, 2006 | 215 | 2006 |
Lipoprotein (a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac‐1 integrin SN Sotiriou, VV Orlova, N Al‐Fakhri, E Ihanus, M Economopoulou, ... The FASEB journal 20 (3), 559-561, 2006 | 202 | 2006 |
Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis HF Langer, KJ Chung, VV Orlova, EY Choi, S Kaul, MJ Kruhlak, ... Blood, The Journal of the American Society of Hematology 116 (22), 4395-4403, 2010 | 199 | 2010 |
Complex tissue and disease modeling using hiPSCs R Passier, V Orlova, C Mummery Cell stem cell 18 (3), 309-321, 2016 | 184 | 2016 |
Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device AD van der Meer, VV Orlova, P ten Dijke, A van den Berg, CL Mummery Lab on a Chip 13 (18), 3562-3568, 2013 | 179 | 2013 |
The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms AN Athanasopoulos, M Economopoulou, VV Orlova, A Sobke, ... Blood 107 (7), 2720-2727, 2006 | 155 | 2006 |
Advanced in vitro models of vascular biology: human induced pluripotent stem cells and organ-on-chip technology A Cochrane, HJ Albers, R Passier, CL Mummery, A van den Berg, ... Advanced drug delivery reviews 140, 68-77, 2019 | 151 | 2019 |
Histone H2AX is integral to hypoxia-driven neovascularization M Economopoulou, HF Langer, A Celeste, VV Orlova, EY Choi, M Ma, ... Nature medicine 15 (5), 553-558, 2009 | 149 | 2009 |
Uncoupling DNA damage from chromatin damage to detoxify doxorubicin X Qiao, SY van der Zanden, DPA Wander, DM Borràs, JY Song, X Li, ... Proceedings of the National Academy of Sciences 117 (26), 15182-15192, 2020 | 130 | 2020 |
Differentiation and functional comparison of monocytes and macrophages from hiPSCs with peripheral blood derivatives X Cao, GK Yakala, FE van den Hil, A Cochrane, CL Mummery, VV Orlova Stem cell reports 12 (6), 1282-1297, 2019 | 95 | 2019 |
Controlling angiogenesis by two unique TGF-β type I receptor signaling pathways VV Orlova, Z Liu, MJ Goumans, P ten Dijke Histology and histopathology, Vol. 26, nº9 (2011), 2011 | 94 | 2011 |