The role of lysosomes in a broad disease-modifying approach evaluated across transgenic mouse models of Alzheimer’s disease and Parkinson’s disease and models of mild cognitive … J Hwang, CM Estick, US Ikonne, D Butler, MC Pait, LH Elliott, S Ruiz, ... International journal of molecular sciences 20 (18), 4432, 2019 | 42 | 2019 |
Aβ42-mediated proteasome inhibition and associated tau pathology in hippocampus are governed by a lysosomal response involving cathepsin B: Evidence for … KLG Farizatto, US Ikonne, MF Almeida, MFR Ferrari, BA Bahr PLoS One 12 (8), e0182895, 2017 | 30 | 2017 |
Rotenone-dependent changes of anterograde motor protein expression and mitochondrial mobility in brain areas related to neurodegenerative diseases TQ Melo, AM D’unhao, SA Martins, KLG Farizatto, RS Chaves, ... Cellular and molecular neurobiology 33, 327-335, 2013 | 24 | 2013 |
Blast waves from detonated military explosive reduce GluR1 and synaptophysin levels in hippocampal slice cultures M Smith, T Piehler, R Benjamin, KL Farizatto, MC Pait, MF Almeida, ... Experimental neurology 286, 107-115, 2016 | 21 | 2016 |
Dynein c1h1, dynactin and syntaphilin expression in brain areas related to neurodegenerative diseases following exposure to rotenone R Chaves, T Melo, A D’Unhao, K Farizatto, M Ferrari Acta Neurobiologiae Experimentalis 73 (4), 541-556, 2013 | 19 | 2013 |
Modulation of tyrosine hydroxylase, neuropeptide Y, glutamate, and substance P in ganglia and brain areas involved in cardiovascular control after chronic exposure to nicotine MFR Ferrari, EF Coelho, KLG Farizatto, G Chadi, DR Fior-Chadi International journal of hypertension 2011 (1), 216464, 2011 | 19 | 2011 |
Astrocyte-synapse interactions during brain development KLG Farizatto, KT Baldwin Current Opinion in Neurobiology 80, 102704, 2023 | 18 | 2023 |
Early synaptic alterations and selective adhesion signaling in hippocampal dendritic zones following organophosphate exposure KLG Farizatto, MF Almeida, RT Long, BA Bahr Scientific Reports 9 (1), 6532, 2019 | 18 | 2019 |
Paraoxon: an anticholinesterase that triggers an excitotoxic cascade of oxidative stress, adhesion responses, and synaptic compromise KLG Farizatto, BA Bahr European scientific journal 13, 29, 2017 | 16 | 2017 |
Inhibitor of endocannabinoid deactivation protects against in vitro and in vivo neurotoxic effects of paraoxon KLG Farizatto, SA McEwan, V Naidoo, SP Nikas, VG Shukla, MF Almeida, ... Journal of Molecular Neuroscience 63, 115-122, 2017 | 14 | 2017 |
Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology M Lamani, MS Malamas, SI Farah, VG Shukla, MF Almeida, CM Weerts, ... Bioorganic & medicinal chemistry 27 (23), 115096, 2019 | 13 | 2019 |
Distinct and dementia‐related synaptopathy in the hippocampus after military blast exposures MF Almeida, T Piehler, KE Carstens, M Zhao, M Samadi, SM Dudek, ... Brain Pathology 31 (3), e12936, 2021 | 12 | 2021 |
Potential Alzheimer’s disease therapeutics among weak cysteine protease inhibitors exhibit mechanistic differences regarding extent of cathepsin B up-regulation and ability to … H Romine, KM Rentschler, K Smith, A Edwards, C Colvin, K Farizatto, ... European scientific journal 13, 38, 2017 | 10 | 2017 |
Lifestyle strategies to promote proteostasis and reduce the risk of Alzheimer’s disease and other proteinopathies MF Almeida, KLG Farizatto, RS Almeida, BA Bahr Ageing Research Reviews 93, 102162, 2024 | 8 | 2024 |
Excitotoxic stimulation activates distinct pathogenic and protective expression signatures in the hippocampus E Caba, MD Sherman, KLG Farizatto, B Alcira, H Wang, C Giardina, ... Journal of Cellular and Molecular Medicine 25 (18), 9011-9027, 2021 | 7 | 2021 |
Estudo da degradação da proteína Tau hiperfosforilada por vias independentes do proteassoma, em modelo experimental de neurodegeneração KLG Farizatto Universidade de São Paulo, 2014 | 1 | 2014 |
Plant Extracts Stimulate the Autophagy-lysosomal Protein Clearance Pathway and Improve Brain Synapse Markers in an Explant Model of Age-related Protein Accumulation Stress … MF de Almeida, M Pait, K Rentschler, KL Farizatto, C Norton, J Tian, ... Current Developments in Nutrition 3, nzz052. FS05-04-19, 2019 | | 2019 |
Inhibitor of Endocannabinoid Deactivation Protects Against In Vitro and In Vivo Neurotoxic Effects of Par.... KLG Farizatto, S McEwan, SP Nikas, VG Shukla | | 2017 |
Detonations of small spherical explosive charges disrupt synaptic integrity and NMDA receptor-cofilin signalling in the absence of neurodegeneration in hippocampal slices M Pait, H Romine, T Piehler, R Benjamin, K Farizatto, M Almeida, L Elliott, ... BRAIN INJURY 31 (6-7), 879-879, 2017 | | 2017 |
Expression of Mitochondrial Molecular Motors in Substantia Nigra Before Neurodegeneration-Related Protein Aggregation. A Study in Primary Cell Cultures and Aged Rats. TQ Melo, RS Chaves, AM D'Unhao, KL Farizatto, MF Ferrari MOLECULAR BIOLOGY OF THE CELL 22, 2011 | | 2011 |