| Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis G Mkrtchyan, V Aleshin, Y Parkhomenko, T Kaehne, M Luigi Di Salvo, ... Scientific reports 5 (1), 12583, 2015 | 141 | 2015 |
| Nuclear morphology is a deep learning biomarker of cellular senescence I Heckenbach, GV Mkrtchyan, MB Ezra, D Bakula, JS Madsen, ... Nature Aging 2 (8), 742-755, 2022 | 68 | 2022 |
| On the role of the mitochondrial 2-oxoglutarate dehydrogenase complex in amino acid metabolism WL Araújo, L Trofimova, G Mkrtchyan, D Steinhauser, L Krall, A Graf, ... Amino acids 44, 683-700, 2013 | 65 | 2013 |
| Mechanisms of non-coenzyme action of thiamine: protein targets and medical significance VA Aleshin, GV Mkrtchyan, VI Bunik Biochemistry (Moscow) 84, 829-850, 2019 | 63 | 2019 |
| Human exonuclease 1 (EXO1) regulatory functions in DNA replication with putative roles in cancer G Keijzers, D Bakula, MA Petr, NGK Madsen, A Teklu, G Mkrtchyan, ... International journal of molecular sciences 20 (1), 74, 2018 | 58 | 2018 |
| ARDD 2020: from aging mechanisms to interventions GV Mkrtchyan, K Abdelmohsen, P Andreux, I Bagdonaite, N Barzilai, ... Aging (Albany NY) 12 (24), 24484, 2020 | 57 | 2020 |
| Up-regulation of 2-oxoglutarate dehydrogenase as a stress response A Graf, L Trofimova, A Loshinskaja, G Mkrtchyan, A Strokina, M Lovat, ... The international journal of biochemistry & cell biology 45 (1), 175-189, 2013 | 56 | 2013 |
| Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex GV Mkrtchyan, M Üçal, A Müllebner, S Dumitrescu, M Kames, R Moldzio, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1859 (9), 925-931, 2018 | 49 | 2018 |
| Inhibition of mitochondrial 2-oxoglutarate dehydrogenase impairs viability of cancer cells in a cell-specific metabolism-dependent manner VI Bunik, G Mkrtchyan, A Grabarska, H Oppermann, D Daloso, WL Araujo, ... Oncotarget 7 (18), 26400, 2016 | 47 | 2016 |
| Multiple forms of glutamate dehydrogenase in animals: structural determinants and physiological implications V Bunik, A Artiukhov, V Aleshin, G Mkrtchyan Biology 5 (4), 53, 2016 | 46 | 2016 |
| Thiamine induces long-term changes in amino acid profiles and activities of 2-oxoglutarate and 2-oxoadipate dehydrogenases in rat brain PM Tsepkova, AV Artiukhov, AI Boyko, VA Aleshin, GV Mkrtchyan, ... Biochemistry (Moscow) 82, 723-736, 2017 | 41 | 2017 |
| Analysis of free amino acids in mammalian brain extracts AL Ksenofontov, AI Boyko, GV Mkrtchyan, VN Tashlitsky, AV Timofeeva, ... Biochemistry (Moscow) 82, 1183-1192, 2017 | 35 | 2017 |
| Mineralization of the connective tissue: a complex molecular process leading to age-related loss of function AV Shindyapina, GV Mkrtchyan, T Gneteeva, S Buiucli, B Tancowny, ... Rejuvenation research 17 (2), 116-133, 2014 | 30 | 2014 |
| Diurnal regulation of the function of the rat brain glutamate dehydrogenase by acetylation and its dependence on thiamine administration VA Aleshin, GV Mkrtchyan, T Kaehne, AV Graf, MV Maslova, VI Bunik Journal of neurochemistry 153 (1), 80-102, 2020 | 26 | 2020 |
| Cellular thiamine status is coupled to function of mitochondrial 2-oxoglutarate dehydrogenase G Mkrtchyan, A Graf, L Bettendorff, V Bunik Neurochemistry international 101, 66-75, 2016 | 26 | 2016 |
| Quantification of rat brain amino acids: analysis of the data consistency L Trofimova, A Ksenofontov, G Mkrtchyan, A Graf, L Baratova, V Bunik Current Analytical Chemistry 12 (4), 349-356, 2016 | 26 | 2016 |
| Aging and drug discovery D Bakula, AM Aliper, P Mamoshina, MA Petr, A Teklu, JA Baur, J Campisi, ... Aging (Albany NY) 10 (11), 3079, 2018 | 25 | 2018 |
| The antioxidant cofactor alpha-lipoic acid may control endogenous formaldehyde metabolism in mammals AV Shindyapina, TV Komarova, EV Sheshukova, NM Ershova, ... Frontiers in Neuroscience 11, 651, 2017 | 24 | 2017 |
| Severe spinal cord injury in rats induces chronic changes in the spinal cord and cerebral cortex metabolism, adjusted by thiamine that improves locomotor performance A Boyko, P Tsepkova, V Aleshin, A Artiukhov, G Mkrtchyan, A Ksenofontov, ... Frontiers in molecular neuroscience 14, 620593, 2021 | 21 | 2021 |
| Positive correlation between rat brain glutamate concentrations and mitochondrial 2-oxoglutarate dehydrogenase activity GV Mkrtchyan, A Graf, L Trofimova, A Ksenofontov, L Baratova, V Bunik Analytical Biochemistry 552, 100-109, 2018 | 17 | 2018 |
