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Martin Duennwald
Martin Duennwald
Associate Professor, University of Western Ontario
在 uwo.ca 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models
DE Ehrnhoefer, M Duennwald, P Markovic, JL Wacker, S Engemann, ...
Human molecular genetics 15 (18), 2743-2751, 2006
4702006
A chaperone pathway in protein disaggregation: Hsp26 alters the nature of protein aggregates to facilitate reactivation by Hsp104
AG Cashikar, M Duennwald, SL Lindquist
Journal of Biological Chemistry 280 (25), 23869-23875, 2005
3772005
The Hsp70/Hsp90 chaperone machinery in neurodegenerative diseases
RE Lackie, A Maciejewski, VG Ostapchenko, J Marques-Lopes, WY Choy, ...
Frontiers in neuroscience 11, 257764, 2017
3592017
Flanking sequences profoundly alter polyglutamine toxicity in yeast
ML Duennwald, S Jagadish, PJ Muchowski, S Lindquist
Proceedings of the National Academy of Sciences 103 (29), 11045-11050, 2006
3512006
Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity
ML Duennwald, S Lindquist
Genes & development 22 (23), 3308-3319, 2008
3502008
Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody
DW Colby, YJ Chu, JP Cassady, M Duennwald, H Zazulak, JM Webster, ...
Proceedings of the National Academy of Sciences 101 (51), 17616-17621, 2004
2362004
Small heat shock proteins potentiate amyloid dissolution by protein disaggregases from yeast and humans
ML Duennwald, AL Echeverria, J Shorter
PLoS biology 10 (6), e1001346, 2012
2072012
Chaperone-dependent amyloid assembly protects cells from prion toxicity
PM Douglas, S Treusch, HY Ren, R Halfmann, ML Duennwald, ...
Proceedings of the National Academy of Sciences 105 (20), 7206-7211, 2008
1992008
A network of protein interactions determines polyglutamine toxicity
ML Duennwald, S Jagadish, F Giorgini, PJ Muchowski, S Lindquist
Proceedings of the National Academy of Sciences 103 (29), 11051-11056, 2006
1742006
Nrf2 and oxidative stress: A general overview of mechanisms and implications in human disease
V Ngo, ML Duennwald
Antioxidants 11 (12), 2345, 2022
1242022
A synergistic small-molecule combination directly eradicates diverse prion strain structures
BE Roberts, ML Duennwald, H Wang, C Chung, NP Lopreiato, ...
Nature chemical biology 5 (12), 936-946, 2009
1152009
Detection of transient in vivo interactions between substrate and transporter during protein translocation into the endoplasmic reticulum
M Dunnwald, A Varshavsky, N Johnsson
Molecular Biology of the Cell 10 (2), 329-344, 1999
1091999
Direct and selective elimination of specific prions and amyloids by 4, 5-dianilinophthalimide and analogs
H Wang, ML Duennwald, BE Roberts, LM Rozeboom, YL Zhang, ...
Proceedings of the National Academy of Sciences 105 (20), 7159-7164, 2008
842008
Impaired heat shock response in cells expressing full-length polyglutamine-expanded huntingtin
SM Chafekar, ML Duennwald
PloS one 7 (5), e37929, 2012
822012
Sec62p, a component of the endoplasmic reticulum protein translocation machinery, contains multiple binding sites for the Sec-complex
S Wittke, M Dunnwald, N Johnsson
Molecular biology of the cell 11 (11), 3859-3871, 2000
722000
Relationships between fungal community composition in decomposing leaf litter and home‐field advantage effects
GF Veen, BL Snoek, T Bakx‐Schotman, DA Wardle, WH van der Putten
Functional Ecology 33 (8), 1524-1535, 2019
682019
Recognition of a Subset of Signal Sequences by Ssh1p, a Sec61p-related Protein in the Membrane of Endoplasmic Reticulum of Yeast Saccharomyces cerevisiae
S Wittke, M Dunnwald, M Albertsen, N Johnsson
Molecular biology of the cell 13 (7), 2223-2232, 2002
682002
Polyglutamine expanded huntingtin dramatically alters the genome-wide binding of HSF1
L Riva, M Koeva, F Yildirim, L Pirhaji, D Dinesh, T Mazor, ML Duennwald, ...
Journal of Huntington's disease 1 (1), 33-45, 2012
592012
Folding or holding?—Hsp70 and Hsp90 chaperoning of misfolded proteins in neurodegenerative disease
BS Rutledge, WY Choy, ML Duennwald
Journal of Biological Chemistry 298 (5), 2022
532022
Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation
SM Chafekar, S Wisén, AD Thompson, AL Echeverria, GM Walter, ...
ACS chemical biology 7 (9), 1556-1564, 2012
432012
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