Biomolecular simulations: From dynamics and mechanisms to computational assays of biological activity DJ Huggins, PC Biggin, MA Dämgen, JW Essex, SA Harris, ... Wiley Interdisciplinary Reviews: Computational Molecular Science 9 (3), e1393, 2019 | 155 | 2019 |
Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD C Cao, X Barros-Álvarez, S Zhang, K Kim, MA Dämgen, O Panova, ... Neuron 110 (19), 3154-3167. e7, 2022 | 74 | 2022 |
Selective G protein signaling driven by substance P–neurokinin receptor dynamics JA Harris, B Faust, AB Gondin, MA Dämgen, CM Suomivuori, NA Veldhuis, ... Nature chemical biology 18 (1), 109-115, 2022 | 55 | 2022 |
A refined open state of the glycine receptor obtained via molecular dynamics simulations MA Dämgen, PC Biggin Structure 28 (1), 130-139. e2, 2020 | 41 | 2020 |
Wiley Interdiscip DJ Huggins, PC Biggin, MA Dämgen, JW Essex, SA Harris, ... Rev.: Comput. Mol. Sci 9 (3), e1393, 2019 | 20 | 2019 |
State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane MA Dämgen, PC Biggin PLOS Computational Biology 17 (2), e1007856, 2021 | 19 | 2021 |
Computational methods to examine conformational changes and ligand-binding properties: Examples in neurobiology MA Dämgen, PC Biggin Neuroscience Letters 700, 9-16, 2019 | 12 | 2019 |
The startle disease mutation E103K impairs activation of human homomeric α1 glycine receptors by disrupting an intersubunit salt bridge across the agonist binding site F Safar, E Hurdiss, M Erotocritou, T Greiner, R Lape, MW Irvine, G Fang, ... Journal of Biological Chemistry 292 (12), 5031-5042, 2017 | 8 | 2017 |
Comment on “On the Functional Annotation of open-channel structures in the glycine receptor” MA Dämgen, AM Zaki, PC Biggin Structure 28 (6), 601-603, 2020 | 2 | 2020 |
Selective G protein signaling driven by substance P-neurokinin receptor structural dynamics JA Harris, B Faust, AB Gondin, MA Dämgen, CM Suomivuori, NA Veldhuis, ... bioRxiv, 2021.05. 16.444192, 2021 | 1 | 2021 |
Signaling Snapshots of 5-HT 2BR Activated by the Prototypical Psychedelic LSD C Cao, X Barros-Álvarez, S Zhang, K Kim, MA Dämgen, O Panova, ... | 1 | |
Heterocyclic compounds as 5ht2a biased agonists J Manish, S SLOCUM, G SKINIOTIS, X BARROS, J Jin, HU KANISKAN, ... | | 2023 |
Investigating the function of a pentameric ligand-gated ion channel with molecular simulation MA Daemgen University of Oxford, 2019 | | 2019 |
Alternative Binding Mode of Full and Partial Agonists in a Pentameric Ligand-Gated Ion Channel Stabilises Loop C in an Open Conformation MA Dämgen, T Greiner, R Lape, LG Sivilotti, PC Biggin Biophysical Journal 114 (3), 297a, 2018 | | 2018 |
Binding Modes of Full and Partial Agonists in the Orthosteric Binding Site of the Glycine Receptor MA Dämgen, T Greiner, R Lape, LG Sivilotti, PC Biggin Biophysical Journal 112 (3), 556a, 2017 | | 2017 |
Henchman, RH,... van der Kamp, MW (2018). Biomolecular simulations: from dynamics and mechanisms to computational assays of biological activity. Wiley Interdisciplinary Reviews … DJ Huggins, PC Biggin, MA Dämgen, JW Essex, SA Harris | | |