Predictive models of lyophilization process for development, scale-up/tech transfer and manufacturing T Zhu, EM Moussa, M Witting, D Zhou, K Sinha, M Hirth, M Gastens, ... European Journal of Pharmaceutics and Biopharmaceutics 128, 363-378, 2018 | 52 | 2018 |
Modeling of molecular nitrogen collisions and dissociation processes for direct simulation Monte Carlo N Parsons, DA Levin, ACT van Duin, T Zhu The Journal of chemical physics 141 (23), 2014 | 45 | 2014 |
Modeling of unsteady shock tube flows using direct simulation Monte Carlo T Zhu, Z Li, DA Levin Journal of Thermophysics and Heat Transfer 28 (4), 623-634, 2014 | 27 | 2014 |
Recommended best practices for lyophilization validation—2021 part I: process design and modeling F Jameel, A Alexeenko, A Bhambhani, G Sacha, T Zhu, S Tchessalov, ... AAPS PharmSciTech 22 (7), 221, 2021 | 19 | 2021 |
Development of a two-dimensional binning model for N2–N relaxation in hypersonic shock conditions T Zhu, Z Li, DA Levin The Journal of Chemical Physics 145 (6), 064302, 2016 | 14 | 2016 |
Development of DSMC chemistry models for nitrogen collisions using accurate theoretical calculations NS Parsons, T Zhu, DA Levin, ACT Van Duin 52nd Aerospace Sciences Meeting, 1213, 2014 | 13 | 2014 |
Recommended best practices for lyophilization validation 2021 part II: process qualification and continued process verification F Jameel, A Alexeenko, A Bhambhani, G Sacha, T Zhu, S Tchessalov, ... AAPS PharmSciTech 22, 1-25, 2021 | 12 | 2021 |
Freeze-dryer equipment capability limit: comparison of computational modeling with experiments at laboratory scale G Shivkumar, V Kshirsagar, T Zhu, IB Sebastiao, SL Nail, GA Sacha, ... Journal of Pharmaceutical Sciences 108 (9), 2972-2981, 2019 | 12 | 2019 |
Multi-point wireless temperature sensing system for monitoring pharmaceutical lyophilization X Jiang, T Zhu, T Kodama, N Raghunathan, A Alexeenko, D Peroulis Frontiers in chemistry 6, 288, 2018 | 11 | 2018 |
Analysis of fractal-like spore aggregates in direct simulation Monte Carlo T Zhu, R Kumar, EV Titov, DA Levin Journal of thermophysics and heat transfer 26 (3), 417-429, 2012 | 9 | 2012 |
Sensitivity study to assess the robustness of primary drying process in pharmaceutical lyophilization N Adhikari, T Zhu, F Jameel, T Tharp, S Shang, A Alexeenko Journal of Pharmaceutical Sciences 109 (2), 1043-1049, 2020 | 6 | 2020 |
DSMC simulation of vibrational excitation and reaction for molecular nitrogen in shock tube flows Z Li, T Zhu, D Levin 51st AIAA Aerospace Sciences Meeting including the New Horizons Forum and …, 2013 | 6 | 2013 |
Chapter 21: Rational Design of a Freeze-Drying Process for Protein Products F Jameel, T Zhu, EM Moussa, BJ Mills Development of Biopharmaceutical Drug-Device Products, 499-537, 2020 | 5 | 2020 |
Simulation of radiation generated by chemical reactions in weakly ionized shock waves using DSMC T Zhu, Z Li, NS Parsons, DA Levin 52nd Aerospace Sciences Meeting, 1212, 2014 | 5 | 2014 |
Chapter 22: development and scale-up of the mixing process for biopharmaceuticals F Jameel, AM Czyzewski, T Zhu, K Sinha, NK Nere Development of Biopharmaceutical Drug-Device Products, 539-565, 2020 | 3 | 2020 |
Chapter 16: Development of robust lyophilization process for therapeutic proteins: a case study EM Moussa, T Zhu, F Jameel Development of biopharmaceutical drug-device products, 391-403, 2020 | 3 | 2020 |
HIGH CONCENTRATION ANTI-TNFalpha ANTIBODY LIQUID FORMULATIONS M Neu, M Tschoepe, C Weber, W Fraunhofer, L Redden, M Gastens, ... US Patent App. 16/101,349, 2019 | 3 | 2019 |
Modeling of NO radiation from unsteady and steady shocks using DSMC T Zhu, Z Li, DA Levin 44th AIAA Thermophysics Conference, 2786, 2013 | 3 | 2013 |
Chapter 19: Design of a Bulk Freeze-Thaw Process for Biologics F Jameel, T Zhu, BJ Mills Development of biopharmaceutical drug-device products, 461-486, 2020 | 2 | 2020 |
Coarse-grained model for N2-N relaxation in hypersonic shock conditions using two-dimensional bins T Zhu, Z Li, DA Levin AIP Conference Proceedings 1786 (1), 2016 | 2 | 2016 |