5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers A Merlo, JG Herman, L Mao, DJ Lee, E Gabrielson, PC Burger, SB Baylin, ... Nature medicine 1 (7), 686-692, 1995 | 2563 | 1995 |
Neoadjuvant PD-1 blockade in resectable lung cancer PM Forde, JE Chaft, KN Smith, V Anagnostou, TR Cottrell, MD Hellmann, ... New England Journal of Medicine 378 (21), 1976-1986, 2018 | 1967 | 2018 |
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors M Esteller, JM Silva, G Dominguez, F Bonilla, X Matias-Guiu, E Lerma, ... JNCI: Journal of the National Cancer Institute 92 (7), 564-569, 2000 | 1519 | 2000 |
Aberrant methylation of p16INK4a is an early event in lung cancer and a potential biomarker for early diagnosis SA Belinsky, KJ Nikula, WA Palmisano, R Michels, G Saccomanno, ... Proceedings of the National Academy of Sciences 95 (20), 11891-11896, 1998 | 1278 | 1998 |
Dysfunctional KEAP1–NRF2 interaction in non-small-cell lung cancer A Singh, V Misra, RK Thimmulappa, H Lee, S Ames, MO Hoque, ... PLoS medicine 3 (10), e420, 2006 | 1210 | 2006 |
Multiple-laboratory comparison of microarray platforms RA Irizarry, D Warren, F Spencer, IF Kim, S Biswal, BC Frank, ... Nature methods 2 (5), 345-350, 2005 | 1064 | 2005 |
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer H Suzuki, E Gabrielson, W Chen, R Anbazhagan, M Van Engeland, ... Nature genetics 31 (2), 141-149, 2002 | 1060 | 2002 |
Collective invasion in breast cancer requires a conserved basal epithelial program KJ Cheung, E Gabrielson, Z Werb, AJ Ewald Cell 155 (7), 1639-1651, 2013 | 882 | 2013 |
Evolution of neoantigen landscape during immune checkpoint blockade in non–small cell lung cancer V Anagnostou, KN Smith, PM Forde, N Niknafs, R Bhattacharya, J White, ... Cancer discovery 7 (3), 264-276, 2017 | 849 | 2017 |
Frequency of homozygous deletion at p16/CDKN2 in primary human tumours P Cairns, TJ Polascik, Y Eby, K Tokino, J Califano, A Merlo, L Mao, ... Nature genetics 11 (2), 210-212, 1995 | 827 | 1995 |
Current WHO guidelines and the critical role of immunohistochemical markers in the subclassification of non-small cell lung carcinoma (NSCLC): Moving from targeted therapy to … L Osmani, F Askin, E Gabrielson, QK Li Seminars in cancer biology 52, 103-109, 2018 | 703 | 2018 |
DNA methylation markers and early recurrence in stage I lung cancer MV Brock, CM Hooker, E Ota-Machida, Y Han, M Guo, S Ames, ... New England Journal of Medicine 358 (11), 1118-1128, 2008 | 700 | 2008 |
Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes CM Heaphy, AP Subhawong, SM Hong, MG Goggins, EA Montgomery, ... The American journal of pathology 179 (4), 1608-1615, 2011 | 567 | 2011 |
Methylation patterns of the E-cadherin 5′ CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression JR Graff, E Gabrielson, H Fujii, SB Baylin, JG Herman Journal of Biological Chemistry 275 (4), 2727-2732, 2000 | 504 | 2000 |
Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy L Casciola-Rosen, K Nagaraju, P Plotz, K Wang, S Levine, E Gabrielson, ... The Journal of experimental medicine 201 (4), 591-601, 2005 | 461 | 2005 |
Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors A Singh, S Venkannagari, KH Oh, YQ Zhang, JM Rohde, L Liu, ... ACS chemical biology 11 (11), 3214-3225, 2016 | 452 | 2016 |
Inactivation of Glutathione S-Transferase P1 Gene by Promoter Hypermethylation in Human Neoplasia M Esteller, PG Corn, JM Urena, E Gabrielson, SB Baylin, JG Herman Cancer research 58 (20), 4515-4518, 1998 | 451 | 1998 |
High-throughput tissue microarray analysis used to evaluate biology and prognostic significance of the E-cadherin pathway in non–small-cell lung cancer RM Bremnes, R Veve, E Gabrielson, FR Hirsch, A Baron, L Bemis, ... Journal of clinical oncology 20 (10), 2417-2428, 2002 | 440 | 2002 |
RNAi-mediated silencing of nuclear factor erythroid-2–related factor 2 gene expression in non–small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy A Singh, S Boldin-Adamsky, RK Thimmulappa, SK Rath, H Ashush, ... Cancer research 68 (19), 7975-7984, 2008 | 433 | 2008 |
Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR E Evron, WC Dooley, CB Umbricht, D Rosenthal, N Sacchi, E Gabrielson, ... The Lancet 357 (9265), 1335-1336, 2001 | 420 | 2001 |