Cell-based delivery of interleukin-13 directs alternative activation of macrophages resulting in improved functional outcome after spinal cord injury D Dooley, E Lemmens, T Vangansewinkel, D Le Blon, C Hoornaert, ... Stem cell reports 7 (6), 1099-1115, 2016 | 79 | 2016 |
Interleukin‐13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages C Guglielmetti, D Le Blon, E Santermans, A Salas‐Perdomo, J Daans, ... Glia 64 (12), 2181-2200, 2016 | 67 | 2016 |
Targeted intracerebral delivery of the anti-inflammatory cytokine IL13 promotes alternative activation of both microglia and macrophages after stroke S Hamzei Taj, D Le Blon, C Hoornaert, J Daans, A Quarta, J Praet, ... Journal of neuroinflammation 15, 1-17, 2018 | 60 | 2018 |
Concise review: innate and adaptive immune recognition of allogeneic and xenogeneic cell transplants in the central nervous system CJ Hoornaert, D Le Blon, A Quarta, J Daans, H Goossens, Z Berneman, ... Stem Cells Translational Medicine 6 (5), 1434-1441, 2017 | 42 | 2017 |
Quantitative and phenotypic analysis of mesenchymal stromal cell graft survival and recognition by microglia and astrocytes in mouse brain N De Vocht, D Lin, J Praet, C Hoornaert, K Reekmans, D Le Blon, ... Immunobiology 218 (5), 696-705, 2013 | 42 | 2013 |
Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model D Le Blon, C Guglielmetti, C Hoornaert, A Quarta, J Daans, D Dooley, ... Journal of neuroinflammation 13, 1-20, 2016 | 39 | 2016 |
Distinct spatial distribution of microglia and macrophages following mesenchymal stem cell implantation in mouse brain D Le Blon, C Hoornaert, J Daans, E Santermans, N Hens, H Goossens, ... Immunology and cell biology 92 (8), 650-658, 2014 | 38 | 2014 |
Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting K Reekmans, N De Vocht, J Praet, E Fransen, D Le Blon, C Hoornaert, ... Stem cell research & therapy 3, 1-10, 2012 | 37 | 2012 |
Tackling the physiological barriers for successful mesenchymal stem cell transplantation into the central nervous system N De Vocht, J Praet, K Reekmans, D Le Blon, C Hoornaert, J Daans, ... Stem cell research & therapy 4, 1-12, 2013 | 29 | 2013 |
In vivo interleukin-13-primed macrophages contribute to reduced alloantigen-specific T cell activation and prolong immunological survival of allogeneic mesenchymal stem cell … CJ Hoornaert, E Luyckx, K Reekmans, M Dhainaut, C Guglielmetti, ... Stem Cells 34 (7), 1971-1984, 2016 | 27 | 2016 |
Early inflammatory responses following cell grafting in the CNS trigger activation of the subventricular zone: a proposed model of sequential cellular events J Praet, E Santermans, J Daans, D Le Blon, C Hoornaert, H Goossens, ... Cell transplantation 24 (8), 1481-1492, 2015 | 27 | 2015 |
Intracerebral delivery of the M2 polarizing cytokine interleukin 13 using mesenchymal stem cell implants in a model of temporal lobe epilepsy in mice I Ali, S Aertgeerts, D Le Blon, D Bertoglio, C Hoornaert, P Ponsaerts, ... Epilepsia 58 (6), 1063-1072, 2017 | 24 | 2017 |
Multimodal imaging of stem cell implantation in the central nervous system of mice N De Vocht, K Reekmans, I Bergwerf, J Praet, C Hoornaert, D Le Blon, ... JoVE (Journal of Visualized Experiments), e3906, 2012 | 21 | 2012 |
Heparin-based, injectable microcarriers for controlled delivery of interleukin-13 to the brain L Schirmer, C Hoornaert, D Le Blon, D Eigel, C Neto, M Gumbleton, ... Biomaterials Science 8 (18), 4997-5004, 2020 | 19 | 2020 |
Murine iPSC-derived microglia and macrophage cell culture models recapitulate distinct phenotypical and functional properties of classical and alternative neuro-immune polarisation A Quarta, D Le Blon, T D'aes, Z Pieters, SH Taj, F Miró-Mur, E Luyckx, ... Brain, Behavior, and Immunity 82, 406-421, 2019 | 19 | 2019 |
Immune remodelling of stromal cell grafts in the central nervous system: therapeutic inflammation or (harmless) side‐effect? D Le Blon, C Hoornaert, JR Detrez, S Bevers, J Daans, H Goossens, ... Journal of Tissue Engineering and Regenerative Medicine 11 (10), 2846-2852, 2017 | 17 | 2017 |
Blood cytokine analysis suggests that SARS-CoV-2 infection results in a sustained tumour promoting environment in cancer patients FHR De Winter, A Hotterbeekx, MT Huizing, A Konnova, E Fransen, ... Cancers 13 (22), 5718, 2021 | 14 | 2021 |
Humoral and cellular immune responses against SARS-CoV-2 after third dose BNT162b2 following double-dose vaccination with BNT162b2 versus ChAdOx1 in patients with cancer Y Debie, JRM Van Audenaerde, T Vandamme, L Croes, LA Teuwen, ... Clinical Cancer Research 29 (3), 635-646, 2023 | 11 | 2023 |
Histological characterization and quantification of cellular events following neural and fibroblast (-like) stem cell grafting in healthy and demyelinated CNS tissue J Praet, E Santermans, K Reekmans, N de Vocht, D Le Blon, C Hoornaert, ... Animal Models for Stem Cell Therapy, 265-283, 2014 | 10 | 2014 |
Quantitative evaluation of stem cell grafting in the central nervous system of mice by in vivo bioluminescence imaging and postmortem multicolor histological analysis K Reekmans, N De Vocht, J Praet, D Le Blon, C Hoornaert, J Daans, ... Imaging and Tracking Stem Cells: Methods and Protocols, 125-141, 2013 | 10 | 2013 |