The ATP switch model for ABC transporters CF Higgins, KJ Linton Nature structural & molecular biology 11 (10), 918-926, 2004 | 1027 | 2004 |
The Escherichia coli ATP‐binding cassette (ABC) proteins KJ Linton, CF Higgins Molecular microbiology 28 (1), 5-13, 1998 | 618 | 1998 |
Structure and function of ABC transporters KJ Linton Physiology 22 (2), 122-130, 2007 | 473 | 2007 |
The human bile salt export pump: characterization of substrate specificity and identification of inhibitors JA Byrne, SS Strautnieks, G Mieli–Vergani, CF Higgins, KJ Linton, ... Gastroenterology 123 (5), 1649-1658, 2002 | 435 | 2002 |
ABC proteins: from bacteria to man IB Holland, SPC Cole, K Kuchler, CF Higgins Elsevier, 2003 | 427 | 2003 |
Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking PH Dixon, N Weerasekera, KJ Linton, O Donaldson, J Chambers, ... Human molecular genetics 9 (8), 1209-1217, 2000 | 397 | 2000 |
Repacking of the transmembrane domains of P‐glycoprotein during the transport ATPase cycle MF Rosenberg, G Velarde, RC Ford, C Martin, G Berridge, ID Kerr, ... The EMBO journal, 2001 | 386 | 2001 |
Structure and function of ABC transporters: the ATP switch provides flexible control KJ Linton, CF Higgins Pflügers Archiv-European Journal of Physiology 453, 555-567, 2007 | 300 | 2007 |
Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes JI Elliott, A Surprenant, FM Marelli-Berg, JC Cooper, RL Cassady-Cain, ... Nature cell biology 7 (8), 808-816, 2005 | 275 | 2005 |
Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy PH Dixon, SWC Van Mil, J Chambers, S Strautnieks, RJ Thompson, ... Gut 58 (4), 537-544, 2009 | 250 | 2009 |
Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre‐messenger RNA splicing JA Byrne, SS Strautnieks, G Ihrke, F Pagani, AS Knisely, KJ Linton, ... Hepatology 49 (2), 553-567, 2009 | 192 | 2009 |
Structure of the multidrug resistance P-glycoprotein CF Higgins, R Callaghan, KJ Linton, MF Rosenberg, RC Ford Seminars in cancer biology 8 (3), 135-142, 1997 | 183 | 1997 |
ABCB4 gene sequence variation in women with intrahepatic cholestasis of pregnancy R Müllenbach, KJ Linton, S Wiltshire, N Weerasekera, J Chambers, ... Journal of medical genetics 40 (5), e70-e70, 2003 | 160 | 2003 |
The human scavenger receptor CD36: glycosylation status and its role in trafficking and function SJ Hoosdally, EJ Andress, C Wooding, CA Martin, KJ Linton Journal of Biological Chemistry 284 (24), 16277-16288, 2009 | 156 | 2009 |
Canalicular ABC transporters and liver disease M Nicolaou, EJ Andress, JK Zolnerciks, PH Dixon, C Williamson, ... The Journal of pathology 226 (2), 300-315, 2012 | 155 | 2012 |
An atomic detail model for the human ATP binding cassette transporter P‐glycoprotein derived from disulphide cross‐linking and homology modeling DR Stenham, JD Campbell, MSP Sansom, CF Higgins, ID Kerr, KJ Linton The FASEB journal 17 (15), 2287-2289, 2003 | 155 | 2003 |
Evidence for a Sav1866‐like architecture for the human multidrug transporter P‐glycoprotein JK Zolnerciks, C Wooding, KJ Linton The FASEB Journal 21 (14), 3937-3948, 2007 | 154 | 2007 |
Investigational ABC transporter inhibitors M Falasca, KJ Linton Expert opinion on investigational drugs 21 (5), 657-666, 2012 | 143 | 2012 |
Complementary functions of the flippase ATP8B1 and the floppase ABCB4 in maintaining canalicular membrane integrity A Groen, MR Romero, C Kunne, SJ Hoosdally, PH Dixon, C Wooding, ... Gastroenterology 141 (5), 1927-1937. e4, 2011 | 141 | 2011 |
P‐glycoprotein in blood–brain barrier endothelial cells: interaction and oligomerization with caveolins J Jodoin, M Demeule, L Fenart, R Cecchelli, S Farmer, KJ Linton, ... Journal of neurochemistry 87 (4), 1010-1023, 2003 | 137 | 2003 |