Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines C Pollard, J Rejman, W De Haes, B Verrier, E Van Gulck, T Naessens, ... Molecular Therapy 21 (1), 251-259, 2013 | 336 | 2013 |
Polyelectrolyte microcapsules as antigen delivery vehicles to dendritic cells: uptake, processing, and cross‐presentation of encapsulated antigens S De Koker, BG De Geest, SK Singh, R De Rycke, T Naessens, ... Angewandte Chemie 121 (45), 8637-8641, 2009 | 245 | 2009 |
Type I interferons interfere with the capacity of mRNA lipoplex vaccines to elicit cytolytic T cell responses A De Beuckelaer, C Pollard, S Van Lint, K Roose, L Van Hoecke, ... Molecular Therapy 24 (11), 2012-2020, 2016 | 134 | 2016 |
Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern S Vander Beken, JR Al Dulayymi, T Naessens, G Koza, M Maza‐Iglesias, ... European journal of immunology 41 (2), 450-460, 2011 | 121 | 2011 |
Biodegradable polyelectrolyte microcapsules: antigen delivery tools with Th17 skewing activity after pulmonary delivery S De Koker, T Naessens, BG De Geest, P Bogaert, J Demeester, ... The journal of immunology 184 (1), 203-211, 2010 | 111 | 2010 |
Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation L Dejager, K Dendoncker, M Eggermont, J Souffriau, ... Mucosal immunology 8 (6), 1212-1225, 2015 | 93 | 2015 |
Where asthma and hypersensitivity pneumonitis meet and differ: noneosinophilic severe asthma P Bogaert, KG Tournoy, T Naessens, J Grooten The American journal of pathology 174 (1), 3-13, 2009 | 93 | 2009 |
Human lymphoid organ cDC2 and macrophages play complementary roles in T follicular helper responses M Durand, T Walter, T Pirnay, T Naessens, P Gueguen, C Goudot, ... Journal of Experimental Medicine 216 (7), 1561-1581, 2019 | 78 | 2019 |
Hybrid pulmonary surfactant-coated nanogels mediate efficient in vivo delivery of siRNA to murine alveolar macrophages L De Backer, T Naessens, S De Koker, E Zagato, J Demeester, J Grooten, ... Journal of Controlled Release 217, 53-63, 2015 | 75 | 2015 |
Inflammatory signatures for eosinophilic vs. neutrophilic allergic pulmonary inflammation reveal critical regulatory checkpoints P Bogaert, T Naessens, S De Koker, B Hennuy, J Hacha, M Smet, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 300 (5 …, 2011 | 67 | 2011 |
Human lung conventional dendritic cells orchestrate lymphoid neogenesis during chronic obstructive pulmonary disease T Naessens, Y Morias, E Hamrud, U Gehrmann, R Budida, J Mattsson, ... American journal of respiratory and critical care medicine 202 (4), 535-548, 2020 | 50 | 2020 |
Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12 S De Koker, L Van Hoecke, A De Beuckelaer, K Roose, K Deswarte, ... Scientific reports 7 (1), 5986, 2017 | 44 | 2017 |
E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo J Van den Bossche, D Laoui, T Naessens, HH Smits, CH Hokke, ... Scientific reports 5 (1), 12599, 2015 | 40 | 2015 |
Innate imprinting of murine resident alveolar macrophages by allergic bronchial inflammation causes a switch from hypoinflammatory to hyperinflammatory reactivity T Naessens, S Vander Beken, P Bogaert, N Van Rooijen, S Lienenklaus, ... The American journal of pathology 181 (1), 174-184, 2012 | 31 | 2012 |
Cholesterol‐sensing liver X receptors stimulate Th2‐driven allergic eosinophilic asthma in mice M Smet, L Van Hoecke, A De Beuckelaer, S Vander Beken, T Naessens, ... Immunity, Inflammation and Disease 4 (3), 350-361, 2016 | 23 | 2016 |
GM-CSF treatment prevents respiratory syncytial virus–induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation T Naessens, B Schepens, M Smet, C Pollard, L Van Hoecke, ... Journal of Allergy and Clinical Immunology 137 (3), 700-709. e9, 2016 | 23 | 2016 |
Non-heme iron overload impairs monocyte to macrophage differentiation via mitochondrial oxidative stress Y Cui, S Gutierrez, S Ariai, L Öberg, K Thörn, U Gehrmann, SM Cloonan, ... Frontiers in Immunology 13, 998059, 2022 | 6 | 2022 |
Molecular therapy: the journal of the American Society of Gene Therapy 2016, 24, 2012; b) A. De Beuckelaer, J. Grooten, S. De Koker A De Beuckelaer, C Pollard, S Van Lint, K Roose, L Van Hoecke, ... Trends in molecular medicine 23, 216, 2017 | 2 | 2017 |
Human lung CD1c dendritic cells orchestrate lymphoid neogenesis during COPD T Naessens, Y Morias, E Hamrud, U Gehrmann, J Mattsson, G Skogberg, ... European Respiratory Journal 54 (suppl 63), 2019 | 1 | 2019 |
Identification And Functional Characterization Of Novel Dendritic Cell Subsets In Chronic Obstructive Pulmonary Disease (COPD) Lung T Naessens, Y Morias, B Lambrecht, D Cunoosamy C107. IMMUNITY, EXACERBATION AND IMMUNE CELL FUNCTION IN COPD, A6327-A6327, 2016 | 1 | 2016 |