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Thomas Naessens
Thomas Naessens
RIA iMED, AstraZeneca
在 astrazeneca.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines
C Pollard, J Rejman, W De Haes, B Verrier, E Van Gulck, T Naessens, ...
Molecular Therapy 21 (1), 251-259, 2013
3362013
Polyelectrolyte microcapsules as antigen delivery vehicles to dendritic cells: uptake, processing, and cross‐presentation of encapsulated antigens
S De Koker, BG De Geest, SK Singh, R De Rycke, T Naessens, ...
Angewandte Chemie 121 (45), 8637-8641, 2009
2452009
Type I interferons interfere with the capacity of mRNA lipoplex vaccines to elicit cytolytic T cell responses
A De Beuckelaer, C Pollard, S Van Lint, K Roose, L Van Hoecke, ...
Molecular Therapy 24 (11), 2012-2020, 2016
1342016
Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern
S Vander Beken, JR Al Dulayymi, T Naessens, G Koza, M Maza‐Iglesias, ...
European journal of immunology 41 (2), 450-460, 2011
1212011
Biodegradable polyelectrolyte microcapsules: antigen delivery tools with Th17 skewing activity after pulmonary delivery
S De Koker, T Naessens, BG De Geest, P Bogaert, J Demeester, ...
The journal of immunology 184 (1), 203-211, 2010
1112010
Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation
L Dejager, K Dendoncker, M Eggermont, J Souffriau, ...
Mucosal immunology 8 (6), 1212-1225, 2015
932015
Where asthma and hypersensitivity pneumonitis meet and differ: noneosinophilic severe asthma
P Bogaert, KG Tournoy, T Naessens, J Grooten
The American journal of pathology 174 (1), 3-13, 2009
932009
Human lymphoid organ cDC2 and macrophages play complementary roles in T follicular helper responses
M Durand, T Walter, T Pirnay, T Naessens, P Gueguen, C Goudot, ...
Journal of Experimental Medicine 216 (7), 1561-1581, 2019
782019
Hybrid pulmonary surfactant-coated nanogels mediate efficient in vivo delivery of siRNA to murine alveolar macrophages
L De Backer, T Naessens, S De Koker, E Zagato, J Demeester, J Grooten, ...
Journal of Controlled Release 217, 53-63, 2015
752015
Inflammatory signatures for eosinophilic vs. neutrophilic allergic pulmonary inflammation reveal critical regulatory checkpoints
P Bogaert, T Naessens, S De Koker, B Hennuy, J Hacha, M Smet, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 300 (5 …, 2011
672011
Human lung conventional dendritic cells orchestrate lymphoid neogenesis during chronic obstructive pulmonary disease
T Naessens, Y Morias, E Hamrud, U Gehrmann, R Budida, J Mattsson, ...
American journal of respiratory and critical care medicine 202 (4), 535-548, 2020
502020
Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12
S De Koker, L Van Hoecke, A De Beuckelaer, K Roose, K Deswarte, ...
Scientific reports 7 (1), 5986, 2017
442017
E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo
J Van den Bossche, D Laoui, T Naessens, HH Smits, CH Hokke, ...
Scientific reports 5 (1), 12599, 2015
402015
Innate imprinting of murine resident alveolar macrophages by allergic bronchial inflammation causes a switch from hypoinflammatory to hyperinflammatory reactivity
T Naessens, S Vander Beken, P Bogaert, N Van Rooijen, S Lienenklaus, ...
The American journal of pathology 181 (1), 174-184, 2012
312012
Cholesterol‐sensing liver X receptors stimulate Th2‐driven allergic eosinophilic asthma in mice
M Smet, L Van Hoecke, A De Beuckelaer, S Vander Beken, T Naessens, ...
Immunity, Inflammation and Disease 4 (3), 350-361, 2016
232016
GM-CSF treatment prevents respiratory syncytial virus–induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation
T Naessens, B Schepens, M Smet, C Pollard, L Van Hoecke, ...
Journal of Allergy and Clinical Immunology 137 (3), 700-709. e9, 2016
232016
Non-heme iron overload impairs monocyte to macrophage differentiation via mitochondrial oxidative stress
Y Cui, S Gutierrez, S Ariai, L Öberg, K Thörn, U Gehrmann, SM Cloonan, ...
Frontiers in Immunology 13, 998059, 2022
62022
Molecular therapy: the journal of the American Society of Gene Therapy 2016, 24, 2012; b) A. De Beuckelaer, J. Grooten, S. De Koker
A De Beuckelaer, C Pollard, S Van Lint, K Roose, L Van Hoecke, ...
Trends in molecular medicine 23, 216, 2017
22017
Human lung CD1c dendritic cells orchestrate lymphoid neogenesis during COPD
T Naessens, Y Morias, E Hamrud, U Gehrmann, J Mattsson, G Skogberg, ...
European Respiratory Journal 54 (suppl 63), 2019
12019
Identification And Functional Characterization Of Novel Dendritic Cell Subsets In Chronic Obstructive Pulmonary Disease (COPD) Lung
T Naessens, Y Morias, B Lambrecht, D Cunoosamy
C107. IMMUNITY, EXACERBATION AND IMMUNE CELL FUNCTION IN COPD, A6327-A6327, 2016
12016
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