Single-cell sequencing of the healthy and diseased heart reveals cytoskeleton-associated protein 4 as a new modulator of fibroblasts activation MM Gladka, B Molenaar, H De Ruiter, S Van Der Elst, H Tsui, D Versteeg, ... Circulation 138 (2), 166-180, 2018 | 289 | 2018 |
Reduced exploration, increased anxiety, and altered social behavior: Autistic-like features of euchromatin histone methyltransferase 1 heterozygous knockout mice MCM Balemans, MMH Huibers, NWD Eikelenboom, AJ Kuipers, ... Behavioural brain research 208 (1), 47-55, 2010 | 159 | 2010 |
Droplet digital PCR for detection and quantification of circulating tumor DNA in plasma of head and neck cancer patients JH van Ginkel, MMH Huibers, RJJ van Es, R de Bree, SM Willems BMC cancer 17, 1-8, 2017 | 136 | 2017 |
The use of droplet digital PCR in liquid biopsies: a highly sensitive technique for MYD88 p.(L265P) detection in cerebrospinal fluid LS Hiemcke‐Jiwa, MC Minnema, JH Radersma‐van Loon, NM Jiwa, ... Hematological oncology 36 (2), 429-435, 2018 | 117 | 2018 |
Tomo-Seq identifies SOX9 as a key regulator of cardiac fibrosis during ischemic injury GPA Lacraz, JP Junker, MM Gladka, B Molenaar, KT Scholman, ... Circulation 136 (15), 1396-1409, 2017 | 104 | 2017 |
Preanalytical blood sample workup for cell‐free DNA analysis using droplet digital PCR for future molecular cancer diagnostics JH van Ginkel, DA van den Broek, J van Kuik, D Linders, R de Weger, ... Cancer medicine 6 (10), 2297-2307, 2017 | 102 | 2017 |
Potential diagnosis of vitreoretinal lymphoma by detection of MYD88 mutation in aqueous humor with ultrasensitive droplet digital polymerase chain reaction LS Hiemcke-Jiwa, NH Ten Dam-van Loon, RJ Leguit, S Nierkens, ... JAMA ophthalmology 136 (10), 1098-1104, 2018 | 82 | 2018 |
Reduced Euchromatin histone methyltransferase 1 causes developmental delay, hypotonia, and cranial abnormalities associated with increased bone gene expression in Kleefstra … MCM Balemans, M Ansar, AR Oudakker, APM van Caam, B Bakker, ... Developmental biology 386 (2), 395-407, 2014 | 82 | 2014 |
Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner MM Gladka, A Kohela, B Molenaar, D Versteeg, L Kooijman, ... Nature communications 12 (1), 84, 2021 | 75 | 2021 |
Immunological and fibrotic mechanisms in cardiac allograft vasculopathy MAA Jansen, HG Otten, RA de Weger, MMH Huibers Transplantation 99 (12), 2467-2475, 2015 | 70 | 2015 |
Therapeutic delivery of miR-148a suppresses ventricular dilation in heart failure A Raso, E Dirkx, LE Philippen, A Fernandez-Celis, F De Majo, ... Molecular therapy 27 (3), 584-599, 2019 | 68 | 2019 |
Clinical validation of whole genome sequencing for cancer diagnostics P Roepman, E de Bruijn, S van Lieshout, L Schoenmaker, MC Boelens, ... The Journal of Molecular Diagnostics 23 (7), 816-833, 2021 | 64 | 2021 |
The interleukin-33/ST2 pathway is expressed in the failing human heart and associated with pro-fibrotic remodeling of the myocardium CCS Tseng, MMH Huibers, J van Kuik, RA de Weger, A Vink, N de Jonge Journal of cardiovascular translational research 11, 15-21, 2018 | 61 | 2018 |
MYD88 p.(L265P) detection on cell‐free DNA in liquid biopsies of patients with primary central nervous system lymphoma. LS Hiemcke‐Jiwa, RJ Leguit, TJ Snijders, JEC Bromberg, S Nierkens, ... British journal of haematology 185 (5), 2019 | 53 | 2019 |
Liquid biopsies to monitor solid organ transplant function: a review of new biomarkers JGHP Verhoeven, K Boer, RHN Van Schaik, OC Manintveld, ... Therapeutic drug monitoring 40 (5), 515-525, 2018 | 53 | 2018 |
Intimal fibrosis in human cardiac allograft vasculopathy M Huibers, N De Jonge, J Van Kuik, E Siera-De Koning, D Van Wichen, ... Transplant immunology 25 (2-3), 124-132, 2011 | 47 | 2011 |
Soluble ST2 in end‐stage heart failure, before and after support with a left ventricular assist device CCS Tseng, MMH Huibers, LH Gaykema, E Siera‐de Koning, ... European journal of clinical investigation 48 (3), e12886, 2018 | 43 | 2018 |
Molecular analysis in liquid biopsies for diagnostics of primary central nervous system lymphoma: Review of literature and future opportunities LS Hiemcke-Jiwa, RJ Leguit, TJ Snijders, NM Jiwa, JJW Kuiper, ... Critical reviews in oncology/hematology 127, 56-65, 2018 | 41 | 2018 |
The composition of ectopic lymphoid structures suggests involvement of a local immune response in cardiac allograft vasculopathy MMH Huibers, AJ Gareau, A Vink, R Kruit, H Feringa, JMT Beerthuijzen, ... The Journal of Heart and Lung Transplantation 34 (5), 734-745, 2015 | 41 | 2015 |
Increased circulating IgG levels, myocardial immune cells and IgG deposits support a role for an immune response in pre‐and end‐stage heart failure P van den Hoogen, SCA de Jager, MMH Huibers, AH Schoneveld, ... Journal of cellular and molecular medicine 23 (11), 7505-7516, 2019 | 40 | 2019 |