A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration M Di Stefano, I Nascimento-Ferreira, G Orsomando, V Mori, J Gilley, ... Cell Death & Differentiation 22 (5), 731-742, 2015 | 261 | 2015 |
Wallerian degeneration is executed by an NMN-SARM1-dependent late Ca2+ influx but only modestly influenced by mitochondria A Loreto, M Di Stefano, M Gering, L Conforti Cell reports 13 (11), 2539-2552, 2015 | 145 | 2015 |
Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration A Loreto, CS Hill, VL Hewitt, G Orsomando, C Angeletti, J Gilley, C Lucci, ... Neurobiology of disease 134, 104678, 2020 | 114 | 2020 |
NMN deamidase delays wallerian degeneration and rescues axonal defects caused by NMNAT2 deficiency in vivo M Di Stefano, A Loreto, G Orsomando, V Mori, F Zamporlini, RP Hulse, ... Current Biology 27 (6), 784-794, 2017 | 104 | 2017 |
Advances in applying computer-aided drug design for neurodegenerative diseases MM Salman, Z Al-Obaidi, P Kitchen, A Loreto, RM Bill, R Wade-Martins International journal of molecular sciences 22 (9), 4688, 2021 | 97 | 2021 |
Independent prognostic value of tumour diameter and tumour necrosis in upper urinary tract urothelial carcinoma G Simone, R Papalia, A Loreto, C Leonardo, S Sentinelli, M Gallucci BJU international 103 (8), 1052-1057, 2009 | 90 | 2009 |
Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss MA White, Z Lin, E Kim, CM Henstridge, E Pena Altamira, CK Hunt, ... Acta neuropathologica communications 7, 1-16, 2019 | 71 | 2019 |
SARM1 is a multi-functional NAD (P) ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites C Angeletti, A Amici, J Gilley, A Loreto, AG Trapanotto, C Antoniou, ... Iscience 25 (2), 2022 | 60 | 2022 |
Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity PD Mabbitt, A Loreto, MA Déry, AJ Fletcher, M Stanley, KC Pao, NT Wood, ... Nature chemical biology 16 (11), 1227-1236, 2020 | 56 | 2020 |
Relationship among symptom score, prostate volume, and urinary flow rates in 543 patients with and without benign prostatic hyperplasia A Sciarra, G D'Eramo, P Casale, A Loreto, M Buscarini, S Di Nicola, ... The Prostate 34 (2), 121-128, 1998 | 52 | 1998 |
Mitochondrial dysfunction as a trigger of programmed axon death E Merlini, MP Coleman, A Loreto Trends in Neurosciences 45 (1), 53-63, 2022 | 43 | 2022 |
Selective inhibitors of SARM1 targeting an allosteric cysteine in the autoregulatory ARM domain HC Feldman, E Merlini, C Guijas, KE DeMeester, E Njomen, EM Kozina, ... Proceedings of the National Academy of Sciences 119 (35), e2208457119, 2022 | 42 | 2022 |
Relationship among age, prostate‐specific antigen, and prostate volume in men with lower urinary tract symptoms (LUTS) and in different groups of men with and without benign … F Di Silverio, A Sciarra, G D'Eramo, P Casale, A Loreto, F Seccareccia The Prostate 36 (1), 1-7, 1998 | 36 | 1998 |
Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1 A Loreto, C Angeletti, W Gu, A Osborne, B Nieuwenhuis, J Gilley, ... Elife 10, e72823, 2021 | 35 | 2021 |
Novel HDAC6 inhibitors increase tubulin acetylation and rescue axonal transport of mitochondria in a model of Charcot–Marie–Tooth type 2F R Adalbert, A Kaieda, C Antoniou, A Loreto, X Yang, J Gilley, T Hoshino, ... ACS chemical neuroscience 11 (3), 258-267, 2019 | 29 | 2019 |
NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy F Rossi, PC Geiszler, W Meng, MR Barron, M Prior, A Herd-Smith, ... Behavioural brain research 339, 140-152, 2018 | 24 | 2018 |
Sustained exendin-4 secretion through gene therapy targeting salivary glands in two different rodent models of obesity/type 2 diabetes G Di Pasquale, I Dicembrini, L Raimondi, C Pagano, JM Egan, A Cozzi, ... PLoS One 7 (7), e40074, 2012 | 24 | 2012 |
DIMA Ploidy, Gleason Score, Pathological Stage and Serum PSA Levels as Predictors of Disease-Free Survival in CD (1) Prostatic Cancer Patients Submitted to Radical Retropubic … F Di Silverio, G D'Eramo, M Buscarini, A Sciarra, P Casale, S Di Nicola, ... European urology 30 (3), 316-321, 1996 | 24 | 1996 |
Laparoscopic transperitoneal right adrenalectomy for ‘large’tumors R Papalia, G Simone, C Leonardo, A Loreto, R Coppola, S Guaglianone, ... Urologia Internationalis 81 (4), 437-440, 2008 | 20 | 2008 |
The NAD+ precursor NMN activates dSarm to trigger axon degeneration in Drosophila AL Rosell, M Paglione, J Gilley, M Kocia, G Perillo, M Gasparrini, ... Elife 11, e80245, 2022 | 17 | 2022 |