| An organelle-specific protein landscape identifies novel diseases and molecular mechanisms K Boldt, J Van Reeuwijk, Q Lu, K Koutroumpas, TMT Nguyen, Y Texier, ... Nature communications 7 (1), 11491, 2016 | 250 | 2016 |
| Mutations in COX7B cause microphthalmia with linear skin lesions, an unconventional mitochondrial disease A Indrieri, VA Van Rahden, V Tiranti, M Morleo, D Iaconis, R Tammaro, ... The American Journal of Human Genetics 91 (5), 942-949, 2012 | 144 | 2012 |
| Mutations of the Mitochondrial Holocytochrome c–Type Synthase in X-Linked Dominant Microphthalmia with Linear Skin Defects Syndrome I Wimplinger, M Morleo, G Rosenberger, D Iaconis, U Orth, P Meinecke, ... The American Journal of Human Genetics 79 (5), 878-889, 2006 | 126 | 2006 |
| Identification of inhibitors of SARS-CoV-2 3CL-pro enzymatic activity using a small molecule in vitro repurposing screen M Kuzikov, E Costanzi, J Reinshagen, F Esposito, L Vangeel, M Wolf, ... ACS pharmacology & translational science 4 (3), 1096-1110, 2021 | 125 | 2021 |
| Kidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathway A Zullo, D Iaconis, A Barra, A Cantone, N Messaddeq, G Capasso, ... Human molecular genetics 19 (14), 2792-2803, 2010 | 62 | 2010 |
| Natural compounds inhibit SARS-CoV-2 nsp13 unwinding and ATPase enzyme activities A Corona, K Wycisk, C Talarico, C Manelfi, J Milia, R Cannalire, ... ACS Pharmacology & Translational Science 5 (4), 226-239, 2022 | 56 | 2022 |
| The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets D Iaconis, M Monti, M Renda, A van Koppen, R Tammaro, M Chiaravalli, ... Scientific Reports 7 (1), 1224, 2017 | 40 | 2017 |
| L-methionine protects against oxidative stress and mitochondrial dysfunction in an in vitro model of Parkinson’s disease M Catanesi, L Brandolini, M d’Angelo, E Benedetti, MG Tupone, ... Antioxidants 10 (9), 1467, 2021 | 30 | 2021 |
| Regulation of autophagosome biogenesis by OFD1‐mediated selective autophagy M Morleo, S Brillante, U Formisano, L Ferrante, F Carbone, D Iaconis, ... The EMBO Journal 40 (4), e105120, 2021 | 26 | 2021 |
| Disruption of the IQSEC2 transcript in a female with X; autosome translocation t (X; 20)(p11. 2; q11. 2) and a phenotype resembling X-linked infantile spasms (ISSX) syndrome M Morleo, D Iaconis, D Chitayat, I Peluso, R Marzella, A Renieri, F Mari, ... Molecular Medicine Reports 1 (1), 33-39, 2008 | 26 | 2008 |
| The SARS-CoV-2 spike protein binds and modulates estrogen receptors O Solis, AR Beccari, D Iaconis, C Talarico, CA Ruiz-Bedoya, ... Science Advances 8 (48), eadd4150, 2022 | 25 | 2022 |
| Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort A Zaliani, L Vangeel, J Reinshagen, D Iaconis, M Kuzikov, O Keminer, ... Scientific data 9 (1), 405, 2022 | 24 | 2022 |
| The centrosomal/basal body protein OFD1 is required for microtubule organization and cell cycle progression M Alfieri, D Iaconis, R Tammaro, L Perone, G Calì, L Nitsch, ... Tissue and Cell 64, 101369, 2020 | 19 | 2020 |
| The HOPS complex subunit VPS39 controls ciliogenesis through autophagy D Iaconis, C Crina, S Brillante, A Indrieri, M Morleo, B Franco Human Molecular Genetics 29 (6), 1018-1029, 2020 | 18 | 2020 |
| Oral-facial-digital syndrome type I cells exhibit impaired DNA repair; unanticipated consequences of defective OFD1 outside of the cilia network I Abramowicz, G Carpenter, M Alfieri, R Colnaghi, E Outwin, P Parent, ... Human Molecular Genetics 26 (1), 19-32, 2017 | 18 | 2017 |
| Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions L Brandolini, M d’Angelo, R Novelli, V Castelli, C Giorgio, A Sirico, ... Cell death & disease 13 (5), 500, 2022 | 14 | 2022 |
| Characterization of raloxifene as a potential pharmacological agent against SARS-CoV-2 and its variants D Iaconis, L Bordi, G Matusali, C Talarico, C Manelfi, MC Cesta, M Zippoli, ... Cell Death & Disease 13 (5), 498, 2022 | 11 | 2022 |
| S-Carboxymethyl cysteine protects against oxidative stress and mitochondrial impairment in a Parkinson’s disease in vitro model M Catanesi, L Brandolini, M d’Angelo, MG Tupone, E Benedetti, ... Biomedicines 9 (10), 1467, 2021 | 8 | 2021 |
| Development of a novel SNP assay to detect lactase persistence associated genetic variants P De Luca, D Iaconis, E Biffali, C Enza, L de Magistris, G Riegler, ... Molecular Biology Reports 48, 7087-7093, 2021 | 7 | 2021 |
| Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication A Corona, VN Madia, R De Santis, C Manelfi, R Emmolo, D Ialongo, ... Antiviral Research 217, 105697, 2023 | 6 | 2023 |
