Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence K Sliepen, BW Han, I Bontjer, P Mooij, F Garces, AJ Behrens, ... Nature communications 10 (1), 1-16, 2019 | 131 | 2019 |
The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen C Havenar-Daughton, A Sarkar, DW Kulp, L Toy, X Hu, I Deresa, ... Science translational medicine 10 (448), 2018 | 125 | 2018 |
HIV-1 vaccine design through minimizing envelope metastability L He, S Kumar, JD Allen, D Huang, X Lin, CJ Mann, KL Saye-Francisco, ... Science Advances 4 (11), eaau6769, 2018 | 88 | 2018 |
Caspase cleavage sites in the human proteome: CaspDB, a database of predicted substrates S Kumar, BJ van Raam, GS Salvesen, P Cieplak PloS one 9 (10), e110539, 2014 | 78 | 2014 |
Closing and opening holes in the glycan shield of HIV-1 envelope glycoprotein SOSIP trimers can redirect the neutralizing antibody response to the newly unmasked epitopes RP Ringe, P Pugach, CA Cottrell, CC LaBranche, GE Seabright, TJ Ketas, ... Journal of virology 93 (4), e01656-18, 2019 | 69 | 2019 |
Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer A Sarkar, S Bale, AJ Behrens, S Kumar, SK Sharma, N de Val, J Pallesen, ... Nature communications 9 (1), 1-14, 2018 | 52 | 2018 |
CleavPredict: a platform for reasoning about matrix metalloproteinases proteolytic events S Kumar, BI Ratnikov, MD Kazanov, JW Smith, P Cieplak PloS one 10 (5), e0127877, 2015 | 50 | 2015 |
Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies M Yuan, CA Cottrell, G Ozorowski, MJ van Gils, S Kumar, NC Wu, ... Cell Host & Microbe 25 (6), 873-883. e5, 2019 | 48 | 2019 |
Understanding the Specificity of Human Galectin-8C Domain Interactions with Its Glycan Ligands Based on Molecular Dynamics Simulations S Kumar, M Frank, R Schwartz-Albiez PLOS ONE 8 (3), e59761, 2013 | 38 | 2013 |
High-Throughput Multiplexed Peptide-Centric Profiling Illustrates Both Substrate Cleavage Redundancy and Specificity in the MMP Family M Kukreja, SA Shiryaev, P Cieplak, N Muranaka, DA Routenberg, ... Chemistry & biology 22 (8), 1122-1133, 2015 | 33 | 2015 |
Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide S Kumar, A Sarkar, P Pugach, RW Sanders, JP Moore, AB Ward, ... Nature communications 10 (1), 1-10, 2019 | 32 | 2019 |
Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines L He, A Chaudhary, X Lin, C Sou, T Alkutkar, S Kumar, T Ngo, E Kosviner, ... Nature Communications 12 (1), 1-18, 2021 | 26 | 2021 |
Controlling aggregation propensity in A53T mutant of alpha-synuclein causing Parkinson’s disease S Kumar, A Sarkar, D Sundar Biochemical and biophysical research communications 387 (2), 305-309, 2009 | 25 | 2009 |
A cross-neutralizing antibody between HIV-1 and influenza virus CCD Lee, Y Watanabe, NC Wu, J Han, S Kumar, T Pholcharee, ... PLoS pathogens 17 (3), e1009407, 2021 | 24 | 2021 |
ZiF-Predict: a web tool for predicting DNA-binding specificity in C2H2 zinc finger proteins B Molparia, K Goyal, A Sarkar, S Kumar, D Sundar Genomics, Proteomics & Bioinformatics 8 (2), 122-126, 2010 | 20 | 2010 |
A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite S Kumar, B Ju, B Shapero, X Lin, L Ren, L Zhang, D Li, Z Zhou, Y Feng, ... Science Advances 6 (38), eabb1328, 2020 | 18 | 2020 |
Matrix Metalloproteinase (MMP) Proteolysis of the Extracellular Loop of Voltage-gated Sodium Channels and Potential Alterations in Pain Signaling AG Remacle, S Kumar, K Motamedchaboki, P Cieplak, S Hullugundi, ... Journal of Biological Chemistry 290 (38), 22939-22944, 2015 | 16 | 2015 |
Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions TG Caniels, M Medina-Ramírez, J Zhang, A Sarkar, S Kumar, ... Cell Reports Medicine, 2023 | 14 | 2023 |
Role of N-glycosylation in activation of proMMP-9. A molecular dynamics simulations study S Kumar, P Cieplak PloS one 13 (1), e0191157, 2018 | 14 | 2018 |
The G protein-coupled receptors in the pufferfish Takifugu rubripes A Sarkar, S Kumar, D Sundar BMC bioinformatics 12 (1), 1-9, 2011 | 14 | 2011 |