Evaluation of polygenic prediction methodology within a reference-standardized framework O Pain, KP Glanville, SP Hagenaars, S Selzam, AE Fürtjes, HA Gaspar, ... PLoS genetics 17 (5), e1009021, 2021 | 100 | 2021 |
Genome‐wide analysis of adolescent psychotic‐like experiences shows genetic overlap with psychiatric disorders O Pain, F Dudbridge, AG Cardno, D Freeman, Y Lu, S Lundstrom, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 177 …, 2018 | 86 | 2018 |
Delineating the genetic component of gene expression in major depression L Dall’Aglio, CM Lewis, O Pain Biological psychiatry 89 (6), 627-636, 2021 | 62 | 2021 |
A transcriptome-wide association study implicates specific pre-and post-synaptic abnormalities in schizophrenia LS Hall, CW Medway, O Pain, AF Pardiñas, EG Rees, V Escott-Price, ... Human molecular genetics 29 (1), 159-167, 2020 | 62 | 2020 |
Novel insight into the etiology of autism spectrum disorder gained by integrating expression data with genome-wide association statistics O Pain, AJ Pocklington, PA Holmans, NJ Bray, HE O’Brien, LS Hall, ... Biological Psychiatry 86 (4), 265-273, 2019 | 61 | 2019 |
Identification of genes and gene pathways associated with major depressive disorder by integrative brain analysis of rat and human prefrontal cortex transcriptomes K Malki, O Pain, MG Tosto, E Du Rietz, L Carboni, LC Schalkwyk Translational psychiatry 5 (3), e519-e519, 2015 | 54 | 2015 |
Transcriptome analysis of genes and gene networks involved in aggressive behavior in mouse and zebrafish K Malki, E Du Rietz, WE Crusio, O Pain, J Paya‐Cano, RL Karadaghi, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 171 …, 2016 | 42 | 2016 |
Impute. me: an open-source, non-profit tool for using data from direct-to-consumer genetic testing to calculate and interpret polygenic risk scores L Folkersen, O Pain, A Ingason, T Werge, CM Lewis, J Austin Frontiers in genetics 11, 578, 2020 | 39 | 2020 |
A systematic review of genome-wide research on psychotic experiences and negative symptom traits: new revelations and implications for psychiatry A Ronald, O Pain Human Molecular Genetics 27 (R2), R136-R152, 2018 | 38 | 2018 |
Are your covariates under control? How normalization can re-introduce covariate effects O Pain, F Dudbridge, A Ronald European Journal of Human Genetics 26 (8), 1194-1201, 2018 | 36 | 2018 |
Genes and gene networks implicated in aggression related behaviour K Malki, O Pain, E Du Rietz, MG Tosto, J Paya-Cano, KN Sandnabba, ... Neurogenetics 15, 255-266, 2014 | 36 | 2014 |
Identifying the common genetic basis of antidepressant response O Pain, K Hodgson, V Trubetskoy, S Ripke, VS Marshe, MJ Adams, ... Biological psychiatry global open science 2 (2), 115-126, 2022 | 34 | 2022 |
Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders LS Hall, O Pain, HE O’Brien, R Anney, JTR Walters, MJ Owen, ... Molecular psychiatry 26 (6), 2082-2088, 2021 | 32 | 2021 |
Transcriptome-wide association study of treatment-resistant depression and depression subtypes for drug repurposing C Fabbri, O Pain, SP Hagenaars, CM Lewis, A Serretti Neuropsychopharmacology 46 (10), 1821-1829, 2021 | 29 | 2021 |
Genetic overlap between psychotic experiences in the community across age and with psychiatric disorders W Barkhuizen, O Pain, F Dudbridge, A Ronald Translational Psychiatry 10 (1), 86, 2020 | 28 | 2020 |
Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank KP Glanville, JRI Coleman, DM Howard, O Pain, KB Hanscombe, B Jermy, ... BJPsych open 7 (2), e44, 2021 | 27 | 2021 |
A tool for translating polygenic scores onto the absolute scale using summary statistics O Pain, AC Gillett, JC Austin, L Folkersen, CM Lewis European Journal of Human Genetics 30 (3), 339-348, 2022 | 19 | 2022 |
Highly polygenic architecture of antidepressant treatment response: comparative analysis of SSRI and NRI treatment in an animal model of depression K Malki, MG Tosto, H Mouriño‐Talín, S Rodríguez‐Lorenzo, O Pain, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 174 …, 2017 | 15 | 2017 |
Comparative mRNA analysis of behavioral and genetic mouse models of aggression K Malki, MG Tosto, O Pain, F Sluyter, YS Mineur, WE Crusio, S de Boer, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 171 …, 2016 | 15 | 2016 |
Impute. me: an open source, non-profit tool for using data from DTC genetic testing to calculate and interpret polygenic risk scores L Folkersen, O Pain, A Ingasson, T Werge, CM Lewis, J Austin BioRxiv, 861831, 2019 | 13 | 2019 |