Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells EJ Brea, CY Oh, E Manchado, S Budhu, RS Gejman, G Mo, P Mondello, ... Cancer immunology research 4 (11), 936-947, 2016 | 172 | 2016 |
Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma P Mondello, S Tadros, M Teater, L Fontan, AY Chang, N Jain, H Yang, ... Cancer discovery 10 (3), 440-459, 2020 | 137 | 2020 |
Rejection of immunogenic tumor clones is limited by clonal fraction RS Gejman, AY Chang, HF Jones, K DiKun, AA Hakimi, A Schietinger, ... Elife 7, e41090, 2018 | 126 | 2018 |
A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens AY Chang, T Dao, RS Gejman, CA Jarvis, A Scott, L Dubrovsky, ... The Journal of clinical investigation 127 (7), 2705-2718, 2017 | 114 | 2017 |
Opportunities and challenges for TCR mimic antibodies in cancer therapy AY Chang, RS Gejman, EJ Brea, CY Oh, MD Mathias, D Pankov, E Casey, ... Expert Opinion on Biological Therapy 16 (8), 979-987, 2016 | 67 | 2016 |
Engineering CAR-T cells to activate small-molecule drugs in situ TJ Gardner, JP Lee, CM Bourne, D Wijewarnasuriya, N Kinarivala, ... Nature chemical biology 18 (2), 216-225, 2022 | 61 | 2022 |
Self-renewal and toll-like receptor signaling sustain exhausted plasmacytoid dendritic cells during chronic viral infection M Macal, Y Jo, S Dallari, AY Chang, J Dai, S Swaminathan, EJ Wehrens, ... Immunity 48 (4), 730-744. e5, 2018 | 60 | 2018 |
Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265P mutations P Mondello, EJ Brea, E De Stanchina, E Toska, AY Chang, M Fennell, ... JCI insight 2 (6), 2017 | 53 | 2017 |
T cell receptor mimic antibodies for cancer therapy L Dubrovsky, T Dao, RS Gejman, EJ Brea, AY Chang, CY Oh, E Casey, ... Oncoimmunology 5 (1), e1049803, 2016 | 48 | 2016 |
ALK and RET inhibitors promote HLA class I antigen presentation and unmask new antigens within the tumor immunopeptidome CY Oh, MG Klatt, C Bourne, T Dao, MM Dacek, EJ Brea, SS Mun, ... Cancer immunology research 7 (12), 1984-1997, 2019 | 44 | 2019 |
Identification of the targets of T-cell receptor therapeutic agents and cells by use of a high-throughput genetic platform RS Gejman, HF Jones, MG Klatt, AY Chang, CY Oh, SS Chandran, ... Cancer immunology research 8 (5), 672-684, 2020 | 34 | 2020 |
Kinase regulation of human MHC class I molecule expression on cancer cells. Cancer Immunol Res. 2016; 4: 936–947. doi: 10.1158/2326-6066 EJ Brea, CY Oh, E Manchado, S Budhu, RS Gejman, G Mo, P Mondello, ... CIR-16-0177, 0 | 30 | |
Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma. Cancer Discov. 2020; 10: 440–459. doi: 10.1158/2159-8290 P Mondello, S Tadros, M Teater, L Fontan, AY Chang, N Jain, H Yang, ... CD-19-0116.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 2020 | 15* | 2020 |
Modulation of SF3B1 in the pre-mRNA spliceosome induces a RIG-I-dependent type I IFN response AY Chang, YJ Zhou, S Iyengar, PW Pobiarzyn, P Tishchenko, KM Shah, ... Journal of Biological Chemistry 297 (5), 2021 | 13 | 2021 |
CD47 blockade enhances therapeutic activity of TCR mimic antibodies to ultra-low density cancer epitopes MD Mathias, JT Sockolosky, AY Chang, KS Tan, C Liu, KC Garcia, ... Leukemia 31 (10), 2254-2257, 2017 | 13 | 2017 |
A dual-receptor T-cell platform with Ab-TCR and costimulatory receptor achieves specificity and potency against AML T Dao, G Xiong, SS Mun, J Meyerberg, T Korontsvit, J Xiang, Z Cui, ... Blood 143 (6), 507-521, 2024 | 12 | 2024 |
A therapeutic TCR mimic monoclonal antibody for intracellular PRAME protein in leukemias A Chang, T Dao, A Scott, L Dubrovsky, C Liu, DA Scheinberg Blood, The Journal of the American Society of Hematology 126 (23), 2527-2527, 2015 | 11 | 2015 |
A PD-1-targeted, receptor-masked IL-2 immunocytokine with maintained potential to engage endogenous IL-2Ra drives selective stimulation of PD-1+ T cells and … J Wu, N Bloch, A Chang, R Bhavsar, S Patel, Q Wang, HS Ahmed, V Garg, ... Cancer Research 83 (7_Supplement), 4434-4434, 2023 | 1 | 2023 |
A TCR Mimic Antibody Targets Immunoproteasome-Regulated Prame Peptide/HLA-I Antigens for Cancer Therapy AY Chang Weill Medical College of Cornell University, 2018 | 1 | 2018 |
CD47 blockade enhances therapeutic activity of TCR mimic antibodies to ultra-low density cancer epitopes through cytokine feed forward mechanisms MD Mathias, JT Sockolosky, AYY Chang, C Liu, KC Garcia, ... Blood, The Journal of the American Society of Hematology 128 (22), 4048-4048, 2016 | 1 | 2016 |