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Aaron Y Chang
Aaron Y Chang
在 regeneron.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells
EJ Brea, CY Oh, E Manchado, S Budhu, RS Gejman, G Mo, P Mondello, ...
Cancer immunology research 4 (11), 936-947, 2016
1722016
Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma
P Mondello, S Tadros, M Teater, L Fontan, AY Chang, N Jain, H Yang, ...
Cancer discovery 10 (3), 440-459, 2020
1372020
Rejection of immunogenic tumor clones is limited by clonal fraction
RS Gejman, AY Chang, HF Jones, K DiKun, AA Hakimi, A Schietinger, ...
Elife 7, e41090, 2018
1262018
A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens
AY Chang, T Dao, RS Gejman, CA Jarvis, A Scott, L Dubrovsky, ...
The Journal of clinical investigation 127 (7), 2705-2718, 2017
1142017
Opportunities and challenges for TCR mimic antibodies in cancer therapy
AY Chang, RS Gejman, EJ Brea, CY Oh, MD Mathias, D Pankov, E Casey, ...
Expert Opinion on Biological Therapy 16 (8), 979-987, 2016
672016
Engineering CAR-T cells to activate small-molecule drugs in situ
TJ Gardner, JP Lee, CM Bourne, D Wijewarnasuriya, N Kinarivala, ...
Nature chemical biology 18 (2), 216-225, 2022
612022
Self-renewal and toll-like receptor signaling sustain exhausted plasmacytoid dendritic cells during chronic viral infection
M Macal, Y Jo, S Dallari, AY Chang, J Dai, S Swaminathan, EJ Wehrens, ...
Immunity 48 (4), 730-744. e5, 2018
602018
Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265P mutations
P Mondello, EJ Brea, E De Stanchina, E Toska, AY Chang, M Fennell, ...
JCI insight 2 (6), 2017
532017
T cell receptor mimic antibodies for cancer therapy
L Dubrovsky, T Dao, RS Gejman, EJ Brea, AY Chang, CY Oh, E Casey, ...
Oncoimmunology 5 (1), e1049803, 2016
482016
ALK and RET inhibitors promote HLA class I antigen presentation and unmask new antigens within the tumor immunopeptidome
CY Oh, MG Klatt, C Bourne, T Dao, MM Dacek, EJ Brea, SS Mun, ...
Cancer immunology research 7 (12), 1984-1997, 2019
442019
Identification of the targets of T-cell receptor therapeutic agents and cells by use of a high-throughput genetic platform
RS Gejman, HF Jones, MG Klatt, AY Chang, CY Oh, SS Chandran, ...
Cancer immunology research 8 (5), 672-684, 2020
342020
Kinase regulation of human MHC class I molecule expression on cancer cells. Cancer Immunol Res. 2016; 4: 936–947. doi: 10.1158/2326-6066
EJ Brea, CY Oh, E Manchado, S Budhu, RS Gejman, G Mo, P Mondello, ...
CIR-16-0177, 0
30
Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma. Cancer Discov. 2020; 10: 440–459. doi: 10.1158/2159-8290
P Mondello, S Tadros, M Teater, L Fontan, AY Chang, N Jain, H Yang, ...
CD-19-0116.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 2020
15*2020
Modulation of SF3B1 in the pre-mRNA spliceosome induces a RIG-I-dependent type I IFN response
AY Chang, YJ Zhou, S Iyengar, PW Pobiarzyn, P Tishchenko, KM Shah, ...
Journal of Biological Chemistry 297 (5), 2021
132021
CD47 blockade enhances therapeutic activity of TCR mimic antibodies to ultra-low density cancer epitopes
MD Mathias, JT Sockolosky, AY Chang, KS Tan, C Liu, KC Garcia, ...
Leukemia 31 (10), 2254-2257, 2017
132017
A dual-receptor T-cell platform with Ab-TCR and costimulatory receptor achieves specificity and potency against AML
T Dao, G Xiong, SS Mun, J Meyerberg, T Korontsvit, J Xiang, Z Cui, ...
Blood 143 (6), 507-521, 2024
122024
A therapeutic TCR mimic monoclonal antibody for intracellular PRAME protein in leukemias
A Chang, T Dao, A Scott, L Dubrovsky, C Liu, DA Scheinberg
Blood, The Journal of the American Society of Hematology 126 (23), 2527-2527, 2015
112015
A PD-1-targeted, receptor-masked IL-2 immunocytokine with maintained potential to engage endogenous IL-2Ra drives selective stimulation of PD-1+ T cells and …
J Wu, N Bloch, A Chang, R Bhavsar, S Patel, Q Wang, HS Ahmed, V Garg, ...
Cancer Research 83 (7_Supplement), 4434-4434, 2023
12023
A TCR Mimic Antibody Targets Immunoproteasome-Regulated Prame Peptide/HLA-I Antigens for Cancer Therapy
AY Chang
Weill Medical College of Cornell University, 2018
12018
CD47 blockade enhances therapeutic activity of TCR mimic antibodies to ultra-low density cancer epitopes through cytokine feed forward mechanisms
MD Mathias, JT Sockolosky, AYY Chang, C Liu, KC Garcia, ...
Blood, The Journal of the American Society of Hematology 128 (22), 4048-4048, 2016
12016
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