Dual modes of CLOCK: BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock R Ye, CP Selby, YY Chiou, I Ozkan-Dagliyan, S Gaddameedhi, A Sancar Genes & development 28 (18), 1989-1998, 2014 | 253 | 2014 |
KRAS suppression-induced degradation of MYC is antagonized by a MEK5-ERK5 compensatory mechanism AV Vaseva, DR Blake, TSK Gilbert, S Ng, G Hostetter, SH Azam, ... Cancer cell 34 (5), 807-822. e7, 2018 | 151 | 2018 |
Computational design of chemogenetic and optogenetic split proteins O Dagliyan, A Krokhotin, I Ozkan-Dagliyan, A Deiters, CJ Der, KM Hahn, ... Nature communications 9 (1), 4042, 2018 | 90 | 2018 |
Low-dose vertical inhibition of the RAF-MEK-ERK cascade causes apoptotic death of KRAS mutant cancers I Ozkan-Dagliyan, JN Diehl, SD George, A Schaefer, B Papke, ... Cell reports 31 (11), 2020 | 84 | 2020 |
Evaluation of the selectivity and sensitivity of isoform-and mutation-specific RAS antibodies AM Waters, I Ozkan-Dagliyan, AV Vaseva, N Fer, LA Strathern, GA Hobbs, ... Science signaling 10 (498), eaao3332, 2017 | 60 | 2017 |
Combination Therapies with CDK4/6 Inhibitors to Treat KRAS-Mutant Pancreatic Cancer CM Goodwin, AM Waters, JE Klomp, S Javaid, KL Bryant, CA Stalnecker, ... Cancer research 83 (1), 141-157, 2023 | 47 | 2023 |
Formation of Arabidopsis Cryptochrome 2 photobodies in mammalian nuclei: application as an optogenetic DNA damage checkpoint switch I Ozkan-Dagliyan, YY Chiou, R Ye, BH Hassan, N Ozturk, A Sancar Journal of Biological Chemistry 288 (32), 23244-23251, 2013 | 41 | 2013 |
Some Novel Mannich Bases of 5‐(3,4‐Dichlorophenyl)‐1,3,4‐oxadiazole‐2(3H)‐one and Their Anti‐Inflammatory Activity M Koksal, I Ozkan‐Dagliyan, T Ozyazici, B Kadioglu, H Sipahi, A Bozkurt, ... Archiv der Pharmazie 350 (9), 1700153, 2017 | 21 | 2017 |
Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer JN Diehl, PS Hibshman, I Ozkan-Dagliyan, CM Goodwin, SV Howard, ... Advances in Cancer Research 153, 101-130, 2022 | 9 | 2022 |
Synthesis, Characterization and Antimicrobial Activity of Novel 3, 5-Disubstituted-1, 3, 4-oxadiazole-2-ones I Ozkan-Dagliyan, F Sahin, M Koksal Rev Chim-Bucharest-Orig Ed 64 (5), 534-9, 2013 | 6 | 2013 |
Studies on Synthesis and Anti-inflammatory Activities of Novel 1, 2, 4-Triazolo [3, 4-b]-1, 3, 4-thiadiazines M Koksal, I Ozkan, M Yarim, SS Bilge, A Bozkurt, DD Erol Rev Chim 62, 1069-1072, 2011 | 5 | 2011 |
5-(3, 4-dichlorophenyl)-3-{[4-(2-pyridyl) piperazine-1-yl] methyl}-1, 3, 4-oxadiazole-2 (3H)-one: Synthesis, characterization, X-ray and DFT structures ZS Şahin, İ Özkan, M Köksal, Ş Işık Journal of Structural Chemistry 53, 938-942, 2012 | 1 | 2012 |