Fresh frozen plasma lessens pulmonary endothelial inflammation and hyperpermeability after hemorrhagic shock and is associated with loss of syndecan 1 Z Peng, S Pati, D Potter, R Brown, JB Holcomb, R Grill, K Wataha, ... Shock 40 (3), 195-202, 2013 | 226 | 2013 |
Cathepsin S: investigating an old player in lung disease pathogenesis, comorbidities, and potential therapeutics R Brown, S Nath, A Lora, G Samaha, Z Elgamal, R Kaiser, C Taggart, ... Respiratory Research 21, 1-17, 2020 | 57 | 2020 |
Airway inflammation and host responses in the era of CFTR modulators K Keown, R Brown, DF Doherty, C Houston, MC McKelvey, S Creane, ... International journal of molecular sciences 21 (17), 6379, 2020 | 48 | 2020 |
Targeting of cathepsin S reduces cystic fibrosis-like lung disease DM Small, RR Brown, DF Doherty, A Abladey, Z Zhou-Suckow, ... European Respiratory Journal 53 (3), 2019 | 39 | 2019 |
Proteases, mucus, and mucosal immunity in chronic lung disease MC McKelvey, R Brown, S Ryan, MA Mall, S Weldon, CC Taggart International journal of molecular sciences 22 (9), 5018, 2021 | 32 | 2021 |
The impact of aging in acute respiratory distress syndrome: a clinical and mechanistic overview R Brown, MC McKelvey, S Ryan, S Creane, D Linden, JC Kidney, ... Frontiers in Medicine 7, 589553, 2020 | 28 | 2020 |
Impaired mucus clearance exacerbates allergen-induced type 2 airway inflammation in juvenile mice B Fritzsching, M Hagner, L Dai, S Christochowitz, R Agrawal, ... Journal of Allergy and Clinical Immunology 140 (1), 190-203. e5, 2017 | 25 | 2017 |
Lack of IL-1 receptor signaling reduces spontaneous airway eosinophilia in juvenile mice with muco-obstructive lung disease R Brown, M Paulsen, S Schmidt, J Schatterny, A Frank, S Hirtz, R Delaney, ... American Journal of Respiratory Cell and Molecular Biology 62 (3), 300-309, 2020 | 7 | 2020 |
Characterisation of eppin function: expression and activity in the lung A Scott, A Glasgow, D Small, S Carlile, M McCrudden, D McLean, ... European Respiratory Journal 50 (1), 2017 | 6 | 2017 |
Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult βENaC‐Tg Mice R Brown, DM Small, DF Doherty, L Holsinger, R Booth, R Williams, ... Mediators of Inflammation 2021 (1), 6682657, 2021 | 4 | 2021 |
Genetic deletion of SLPI results in increased protease activity and mucus clearance in a murine model of chronic lung disease P Ferris, R Brown, R Delaney, C Dougan, D Doherty, D Small, M Mall, ... European Respiratory Journal 60 (suppl 66), 2022 | 1 | 2022 |
OPEN ACCESS EDITED BY C Taggart, GS Kesturu, R Brown, X Wu, Z Wang, Z Chen, G Wang, X Xie, ... Oral neutrophils-the good, the bad, and the ugly, 41, 2023 | | 2023 |
Genetic deletion of SLPI promotes inflammatory cell recruitment in a model of chronic lung disease R Brown, P Ferris, C Dougan, R Delaney, D Small, MA Mall, S Weldon, ... European Respiratory Journal 58 (suppl 65), 2021 | | 2021 |
Research Article Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult βENaC-Tg Mice R Brown, DM Small, DF Doherty, L Holsinger, R Booth, R Williams, ... | | 2021 |
P218 Therapeutic inhibition of CatS reduces airway inflammation and mucus plugging but does not prevent the progression of lung tissue damage in adult βENaC-Tg mice RR Brown, DM Small, L Holsinger, R Booth, JS Elborn, MA Mall, ... Journal of Cystic Fibrosis 18, S118-S119, 2019 | | 2019 |
INVESTIGATING THE ROLE OF CATHEPSIN S IN THE PATHOGENESIS OF CYSTIC FIBROSIS-LIKE LUNG DISEASE D Small, R Brown, A Abladey, D Doherty, Z Zhou-Suckow, C Scott, ... PEDIATRIC PULMONOLOGY 52, S249-S250, 2017 | | 2017 |
75 Role of the IL1 signaling pathway in the development of type 2 airway inflammation in juvenile Scnn1b-Tg mice R Brown, S Schmidt, J Schatterny, S Hirtz, MA Mall Journal of Cystic Fibrosis 1 (16), S83, 2017 | | 2017 |
Effects of nutrients and microorganisms on aflatoxin production by Aspergillus flavus during successive generations of subculturing O Omolehin, Y Ruarang, R Brown, Z Chen PHYTOPATHOLOGY 106 (12), 46-46, 2016 | | 2016 |
A role for Cathepsin S in the pathogenesis of cystic fibrosis-like lung disease R Brown Queen's University Belfast, 2016 | | 2016 |
INVESTIGATING THE ROLE OF CATHEPSIN S IN THE PATHOGENESIS OF CYSTIC FIBROSIS-LIKE LUNG DISEASE D Small, R Brown, A Abladey, L Holsinger, R Booth, C Scott, J Elborn, ... PEDIATRIC PULMONOLOGY 50, 242-242, 2015 | | 2015 |