Rapid acquisition and model-based analysis of cell-free transcription–translation reactions from nonmodel bacteria SJ Moore, JT MacDonald, S Wienecke, A Ishwarbhai, A Tsipa, R Aw, ... Proceedings of the National Academy of Sciences 115 (19), E4340-E4349, 2018 | 195 | 2018 |
Development of a Bacillus subtilis cell-free transcription-translation system for prototyping regulatory elements R Kelwick, AJ Webb, JT MacDonald, PS Freemont Metabolic engineering 38, 370-381, 2016 | 136 | 2016 |
Developments in the tools and methodologies of synthetic biology R Kelwick, JT MacDonald, AJ Webb, P Freemont Frontiers in bioengineering and biotechnology 2, 60, 2014 | 118 | 2014 |
One-pot DNA construction for synthetic biology: the Modular Overlap-Directed Assembly with Linkers (MODAL) strategy A Casini, JT MacDonald, JD Jonghe, G Christodoulou, PS Freemont, ... Nucleic acids research 42 (1), e7-e7, 2014 | 118 | 2014 |
Computational design approaches and tools for synthetic biology JT MacDonald, C Barnes, RI Kitney, PS Freemont, GBV Stan Integrative Biology 3 (2), 97-108, 2011 | 109 | 2011 |
Probing the “dark matter” of protein fold space WR Taylor, V Chelliah, SM Hollup, JT MacDonald, I Jonassen Structure 17 (9), 1244-1252, 2009 | 98 | 2009 |
Delineation of metabolic gene clusters in plant genomes by chromatin signatures. Yu N, Nützmann HW, MacDonald JT, Moore B, Field B, Berriri S, Trick M ... Nucleic Acids Research, 2016 | 76 | 2016 |
R2oDNA designer: computational design of biologically neutral synthetic DNA sequences A Casini, G Christodoulou, PS Freemont, GS Baldwin, T Ellis, ... ACS synthetic biology 3 (8), 525-528, 2014 | 70 | 2014 |
High–quality protein backbone reconstruction from alpha carbons using Gaussian mixture models BL Moore, LA Kelley, J Barber, JW Murray, JT MacDonald Journal of computational chemistry 34 (22), 1881-1889, 2013 | 64 | 2013 |
Cell-free synthetic biology for in vitro prototype engineering SJ Moore, JT MacDonald, PS Freemont Biochemical Society Transactions 45 (3), 785-791, 2017 | 47 | 2017 |
De novo backbone scaffolds for protein design JT MacDonald, K Maksimiak, MI Sadowski, WR Taylor Proteins: Structure, Function, and Bioinformatics 78 (5), 1311-1325, 2010 | 47 | 2010 |
OligoArchive: Using DNA in the DBMS storage hierarchy R Appuswamy, K Lebrigand, P Barbry, M Antonini, O Madderson, ... CIDR, 2019 | 46 | 2019 |
Atomic structure of type VI contractile sheath from Pseudomonas aeruginosa O Salih, S He, S Planamente, L Stach, JT MacDonald, E Manoli, ... Structure 26 (2), 329-336. e3, 2018 | 44 | 2018 |
Cell-free protein synthesis as a prototyping platform for mammalian synthetic biology MB Kopniczky, C Canavan, DW McClymont, MA Crone, L Suckling, ... ACS synthetic biology 9 (1), 144-156, 2020 | 39 | 2020 |
A protease-based biosensor for the detection of schistosome cercariae AJ Webb, R Kelwick, MJ Doenhoff, N Kylilis, JT MacDonald, KY Wen, ... Scientific reports 6 (1), 24725, 2016 | 35 | 2016 |
Unfolding crystallins: The destabilizing role of a β‐hairpin cysteine in βB2‐crystallin by simulation and experiment JT Macdonald, AG Purkiss, MA Smith, P Evans, JM Goodfellow, ... Protein science 14 (5), 1282-1292, 2005 | 32 | 2005 |
Structural and mechanistic insight into the Listeria monocytogenes two-enzyme lipoteichoic acid synthesis system I Campeotto, MG Percy, JT MacDonald, A Förster, PS Freemont, ... Journal of Biological Chemistry 289 (41), 28054-28069, 2014 | 31 | 2014 |
Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension JT MacDonald, BV Kabasakal, D Godding, S Kraatz, L Henderson, ... Proceedings of the National Academy of Sciences, 2016 | 29 | 2016 |
Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis D Lu, J Silhan, JT MacDonald, EP Carpenter, K Jensen, CM Tang, ... Proceedings of the National Academy of Sciences 109 (42), 16852-16857, 2012 | 24 | 2012 |
Computational protein design with backbone plasticity JT MacDonald, PS Freemont Biochemical Society Transactions 44, 1523-1529, 2016 | 17 | 2016 |