Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis D Schafflick, CA Xu, M Hartlehnert, M Cole, A Schulte-Mecklenbeck, ... Nature communications 11 (1), 247, 2020 | 290 | 2020 |
Neurological manifestations of COVID-19 feature T cell exhaustion and dedifferentiated monocytes in cerebrospinal fluid M Heming, X Li, S Räuber, AK Mausberg, AL Börsch, M Hartlehnert, ... Immunity 54 (1), 164-175. e6, 2021 | 150 | 2021 |
Peroxisome proliferator-activated receptor-γ modulates the response of macrophages to lipopolysaccharide and glucocorticoids M Heming, S Gran, SL Jauch, L Fischer-Riepe, A Russo, L Klotz, ... Frontiers in immunology 9, 893, 2018 | 141 | 2018 |
Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges D Schafflick, J Wolbert, M Heming, C Thomas, M Hartlehnert, AL Börsch, ... Nature neuroscience 24 (9), 1225-1234, 2021 | 116 | 2021 |
Redefining the heterogeneity of peripheral nerve cells in health and autoimmunity J Wolbert, X Li, M Heming, AK Mausberg, D Akkermann, C Frydrychowicz, ... Proceedings of the National Academy of Sciences 117 (17), 9466-9476, 2020 | 105 | 2020 |
Stroke induces disease-specific myeloid cells in the brain parenchyma and pia C Beuker, D Schafflick, JK Strecker, M Heming, X Li, J Wolbert, ... Nature communications 13 (1), 945, 2022 | 51 | 2022 |
Therapeutic apheresis in acute relapsing multiple sclerosis: current evidence and unmet needs—A systematic review L Rolfes, S Pfeuffer, T Ruck, N Melzer, M Pawlitzki, M Heming, M Brand, ... Journal of clinical medicine 8 (10), 1623, 2019 | 31 | 2019 |
Alemtuzumab-induced immune phenotype and repertoire changes: implications for secondary autoimmunity T Ruck, S Barman, A Schulte-Mecklenbeck, S Pfeuffer, F Steffen, C Nelke, ... Brain 145 (5), 1711-1725, 2022 | 29 | 2022 |
Immune cell profiling of the cerebrospinal fluid provides pathogenetic insights into inflammatory neuropathies M Heming, A Schulte-Mecklenbeck, T Brix, J Wolbert, T Ruland, L Klotz, ... Frontiers in Immunology 10, 515, 2019 | 29 | 2019 |
Cerebrospinal fluid flow cytometry distinguishes psychosis spectrum disorders from differential diagnoses S Räuber, M Heming, J Repple, T Ruland, R Kuelby, ... Molecular psychiatry 26 (12), 7661-7670, 2021 | 27 | 2021 |
Intraocular dendritic cells characterize HLA-B27-associated acute anterior uveitis M Kasper, M Heming, D Schafflick, X Li, T Lautwein, MM Zu Horste, ... Elife 10, e67396, 2021 | 20 | 2021 |
Bcl6 controls meningeal Th17–B cell interaction in murine neuroinflammation M Hartlehnert, AL Börsch, X Li, M Burmeister, H Gerwien, D Schafflick, ... Proceedings of the National Academy of Sciences 118 (36), e2023174118, 2021 | 20 | 2021 |
Leukocyte profiles in blood and CSF distinguish neurosarcoidosis from multiple sclerosis M Heming, L Lohmann, A Schulte-Mecklenbeck, T Brix, CC Gross, ... Journal of Neuroimmunology 341, 577171, 2020 | 20 | 2020 |
Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma M Heming, S Haessner, J Wolbert, IN Lu, X Li, B Brokinkel, M Müther, ... Genome Medicine 14 (1), 109, 2022 | 16 | 2022 |
High-dimensional investigation of the cerebrospinal fluid to explore and monitor CNS immune responses M Heming, AL Börsch, H Wiendl, G Meyer zu Hörste Genome Medicine 14 (1), 94, 2022 | 15 | 2022 |
Pretreatment anti-thyroid autoantibodies indicate increased risk for thyroid autoimmunity secondary to alemtuzumab: a prospective cohort study T Ruck, A Schulte-Mecklenbeck, S Pfeuffer, M Heming, L Klotz, ... EBioMedicine 46, 381-386, 2019 | 14 | 2019 |
Deterministic programming of human pluripotent stem cells into microglia facilitates studying their role in health and disease AM Speicher, L Korn, J Csatári, L Gonzalez-Cano, M Heming, C Thomas, ... Proceedings of the National Academy of Sciences 119 (43), e2123476119, 2022 | 11 | 2022 |
Supporting the differential diagnosis of connective tissue diseases with neurological involvement by blood and cerebrospinal fluid flow cytometry M Heming, L Müller-Miny, L Rolfes, A Schulte-Mecklenbeck, TJ Brix, ... Journal of Neuroinflammation 20 (1), 46, 2023 | 5 | 2023 |
Alemtuzumab treatment exemplifies discordant immune effects of blood and cerebrospinal fluid in multiple sclerosis L Müller-Miny, M Heming, T Lautwein, T Ruck, IN Lu, H Wiendl, ... Journal of Neuroimmunology 378, 578088, 2023 | 3 | 2023 |
Integrated single-cell transcriptomics of cerebrospinal fluid cells in treatment-naïve multiple sclerosis F Straeten, J Zhu, AL Börsch, B Zhang, K Li, IN Lu, C Gross, M Heming, ... Journal of Neuroinflammation 19 (1), 306, 2022 | 3 | 2022 |