Chromosomal translocations in cancer M Nambiar, V Kari, SC Raghavan Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1786 (2), 139-152, 2008 | 234 | 2008 |
Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer E Hessmann, MS Patzak, L Klein, N Chen, V Kari, I Ramu, TE Bapiro, ... Gut 67 (3), 497-507, 2018 | 207 | 2018 |
Stem-cell-like properties and epithelial plasticity arise as stable traits after transient Twist1 activation JM Schmidt, E Panzilius, HS Bartsch, M Irmler, J Beckers, V Kari, ... Cell reports 10 (2), 131-139, 2015 | 197 | 2015 |
Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness V Kari, WY Mansour, SK Raul, SJ Baumgart, A Mund, M Grade, H Sirma, ... EMBO reports 17 (11), 1609-1623, 2016 | 112 | 2016 |
The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair V Kari, A Shchebet, H Neumann, SA Johnsen Cell cycle 10 (20), 3495-3504, 2011 | 98 | 2011 |
Methyl angolensate, a natural tetranortriterpenoid induces intrinsic apoptotic pathway in leukemic cells KK Chiruvella, V Kari, B Choudhary, M Nambiar, RG Ghanta, ... FEBS letters 582 (29), 4066-4076, 2008 | 95 | 2008 |
Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4-and MYC-dependent manner VK Mishra, F Wegwitz, RL Kosinsky, M Sen, R Baumgartner, T Wulff, ... Nucleic acids research 45 (11), 6334-6349, 2017 | 84 | 2017 |
EZH2 Regulates Pancreatic Cancer Subtype Identity and Tumor Progression via Transcriptional Repression of GATA6 S Patil, B Steuber, W Kopp, V Kari, L Urbach, X Wang, S Küffer, ... Cancer research 80 (21), 4620-4632, 2020 | 68 | 2020 |
Krüppel-like transcription factor KLF10 suppresses TGFβ-induced epithelial-to-mesenchymal transition via a negative feedback mechanism VK Mishra, M Subramaniam, V Kari, KS Pitel, SJ Baumgart, RM Naylor, ... Cancer research 77 (9), 2387-2400, 2017 | 60 | 2017 |
A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart LM Iyer, S Nagarajan, M Woelfer, E Schoger, S Khadjeh, MP Zafiriou, ... Nucleic acids research 46 (6), 2850-2867, 2018 | 48 | 2018 |
RNF40 regulates gene expression in an epigenetic context-dependent manner W Xie, S Nagarajan, SJ Baumgart, RL Kosinsky, Z Najafova, V Kari, ... Genome biology 18, 1-22, 2017 | 47 | 2017 |
A subset of histone H2B genes produces polyadenylated mRNAs under a variety of cellular conditions V Kari, O Karpiuk, B Tieg, M Kriegs, E Dikomey, H Krebber, ... PloS one 8 (5), e63745, 2013 | 47 | 2013 |
The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness V Kari, SK Raul, JM Henck, J Kitz, F Kramer, RL Kosinsky, N Übelmesser, ... Clinical epigenetics 11, 1-13, 2019 | 45 | 2019 |
Cytosolic 5′-nucleotidase 1A is overexpressed in pancreatic cancer and mediates gemcitabine resistance by reducing intracellular gemcitabine metabolites MS Patzak, V Kari, S Patil, FH Hamdan, RG Goetze, M Brunner, ... EBioMedicine 40, 394-405, 2019 | 32 | 2019 |
CHD1 regulates cell fate determination by activation of differentiation-induced genes SJ Baumgart, Z Najafova, T Hossan, W Xie, S Nagarajan, V Kari, N Ditzel, ... Nucleic acids research 45 (13), 7722-7735, 2017 | 32 | 2017 |
BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells S Nagarajan, U Bedi, A Budida, FH Hamdan, VK Mishra, Z Najafova, ... Nucleic acids research 45 (6), 3130-3145, 2017 | 28 | 2017 |
The E3 ubiquitin ligase RNF40 suppresses apoptosis in colorectal cancer cells D Schneider, RL Chua, N Molitor, FH Hamdan, EM Rettenmeier, ... Clinical Epigenetics 11, 1-13, 2019 | 27 | 2019 |
Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination HM Wüst, A Wegener, F Fröb, AC Hartwig, F Wegwitz, V Kari, M Schimmel, ... Nucleic acids research 48 (16), 8959-8976, 2020 | 22 | 2020 |
Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment MT Haider, H Saito, J Zarrer, K Uzhunnumpuram, S Nagarajan, V Kari, ... Breast Cancer Research 22, 1-16, 2020 | 20 | 2020 |
Epigenome mapping identifies tumor-specific gene expression in primary rectal cancer H Flebbe, FH Hamdan, V Kari, J Kitz, J Gaedcke, BM Ghadimi, ... Cancers 11 (8), 1142, 2019 | 17 | 2019 |