A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2 S George, JJ Rochford, C Wolfrum, SL Gray, S Schinner, JC Wilson, ... Science 304 (5675), 1325-1328, 2004 | 703 | 2004 |
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay GSH Yeo, CC Connie Hung, J Rochford, J Keogh, J Gray, ... Nature neuroscience 7 (11), 1187-1189, 2004 | 668 | 2004 |
Adipogenesis at a glance CE Lowe, S O'Rahilly, JJ Rochford Journal of cell science 124 (16), 2681-2686, 2011 | 467 | 2011 |
Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY3-36 BG Challis, AP Coll, GSH Yeo, SB Pinnock, SL Dickson, RR Thresher, ... Proceedings of the National Academy of Sciences 101 (13), 4695-4700, 2004 | 464 | 2004 |
Serotonin 5-HT2C Receptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors DD Lam, MJ Przydzial, SH Ridley, GSH Yeo, JJ Rochford, S O’Rahilly, ... Endocrinology 149 (3), 1323-1328, 2008 | 330 | 2008 |
Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways L Zhou, GM Sutton, JJ Rochford, RK Semple, DD Lam, LJ Oksanen, ... Cell metabolism 6 (5), 398-405, 2007 | 274 | 2007 |
Insulin and insulin-like growth factor-I induce vascular endothelial growth factor mRNA expression via different signaling pathways C Miele, JJ Rochford, N Filippa, S Giorgetti-Peraldi, E Van Obberghen Journal of Biological Chemistry 275 (28), 21695-21702, 2000 | 264 | 2000 |
Lipodystrophy: metabolic insights from a rare disorder. I Huang-Doran, A Sleigh, JJ Rochford, S O'Rahilly, DB Savage The Journal of endocrinology 207 (3), 245-255, 2010 | 251 | 2010 |
The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation VA Payne, N Grimsey, A Tuthill, S Virtue, SL Gray, E Dalla Nora, ... Diabetes 57 (8), 2055-2060, 2008 | 241 | 2008 |
C/EBP transcription factors regulate SREBP1c gene expression during adipogenesis VA Payne, WS Au, CE Lowe, SM Rahman, JE Friedman, S O'Rahilly, ... Biochemical Journal 425 (1), 215-224, 2010 | 229 | 2010 |
Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-α C Sewter, D Berger, RV Considine, G Medina, J Rochford, T Ciaraldi, ... Diabetes 51 (4), 1035-1041, 2002 | 193 | 2002 |
Temporal and Spatial Regulation of the Phosphatidate Phosphatases Lipin 1 and 2∗ N Grimsey, GS Han, L O'Hara, JJ Rochford, GM Carman, S Siniossoglou Journal of Biological Chemistry 283 (43), 29166-29174, 2008 | 142 | 2008 |
Nucleus of the solitary tract serotonin 5-HT2C receptors modulate food intake G d'Agostino, D Lyons, C Cristiano, M Lettieri, C Olarte-Sanchez, ... Cell metabolism 28 (4), 619-630. e5, 2018 | 130 | 2018 |
A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia S Dash, H Sano, JJ Rochford, RK Semple, G Yeo, CSS Hyden, MA Soos, ... Proceedings of the National Academy of Sciences 106 (23), 9350-9355, 2009 | 126 | 2009 |
Insulin action in cultured human myoblasts: contribution of different signalling pathways to regulation of glycogen synthesis SJ HUREL, JJ ROCHFORD, AC BORTHWICK, AM WELLS, ... Biochemical Journal 320 (3), 871-877, 1996 | 110 | 1996 |
ETO/MTG8 is an inhibitor of C/EBPβ activity and a regulator of early adipogenesis JJ Rochford, RK Semple, M Laudes, KB Boyle, C Christodoulides, ... Molecular and cellular biology 24 (22), 9863-9872, 2004 | 103 | 2004 |
Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons LK Burke, B Doslikova, G d'Agostino, M Greenwald-Yarnell, T Georgescu, ... Molecular metabolism 5 (3), 245-252, 2016 | 93 | 2016 |
The human lipodystrophy protein seipin is an ER membrane adaptor for the adipogenic PA phosphatase lipin 1 MFM Sim, RJ Dennis, EM Aubry, N Ramanathan, H Sembongi, V Saudek, ... Molecular metabolism 2 (1), 38-46, 2013 | 92 | 2013 |
Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis MMU Talukder, MFM Sim, S O'Rahilly, JM Edwardson, JJ Rochford Molecular Metabolism 4 (3), 199-209, 2015 | 90 | 2015 |
Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis M Laudes, C Christodoulides, C Sewter, JJ Rochford, RV Considine, ... Journal of Biological Chemistry 279 (12), 11711-11718, 2004 | 82 | 2004 |