Organoid modeling of the tumor immune microenvironment JT Neal, X Li, J Zhu, V Giangarra, CL Grzeskowiak, J Ju, IH Liu, SH Chiou, ... Cell 175 (7), 1972-1988. e16, 2018 | 1085 | 2018 |
Nfib promotes metastasis through a widespread increase in chromatin accessibility SK Denny, D Yang, CH Chuang, JJ Brady, JS Lim, BM Grüner, SH Chiou, ... Cell 166 (2), 328-342, 2016 | 343 | 2016 |
Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing SH Chiou, IP Winters, J Wang, S Naranjo, C Dudgeon, FB Tamburini, ... Genes & development 29 (14), 1576-1585, 2015 | 270 | 2015 |
Gpr124 is essential for blood–brain barrier integrity in central nervous system disease J Chang, MR Mancuso, C Maier, X Liang, K Yuki, LU Yang, JW Kwong, ... Nature medicine 23 (4), 450-460, 2017 | 207 | 2017 |
Comprehensive T cell repertoire characterization of non-small cell lung cancer A Reuben, J Zhang, SH Chiou, RM Gittelman, J Li, WC Lee, J Fujimoto, ... Nature communications 11 (1), 603, 2020 | 175 | 2020 |
Up-regulation of inhibitory natural killer receptors CD94/NKG2A with suppressed intracellular perforin expression of tumor-infiltrating CD8+ T lymphocytes in human cervical … BC Sheu, SH Chiou, HH Lin, SN Chow, SC Huang, HN Ho, SM Hsu Cancer Research 65 (7), 2921-2929, 2005 | 161 | 2005 |
Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis CH Chuang, PG Greenside, ZN Rogers, JJ Brady, D Yang, RK Ma, ... Nature medicine 23 (3), 291-300, 2017 | 154 | 2017 |
KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19 J Li, M Zaslavsky, Y Su, J Guo, MJ Sikora, V van Unen, A Christophersen, ... Science 376 (6590), eabi9591, 2022 | 147 | 2022 |
Current concepts of tumor-infiltrating lymphocytes in human malignancies SH Chiou, BC Sheu, WC Chang, SC Huang, H Hong-Nerng Journal of reproductive immunology 67 (1-2), 35-50, 2005 | 126 | 2005 |
Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity IP Winters, SH Chiou, NK Paulk, CD McFarland, PV Lalgudi, RK Ma, ... Nature communications 8 (1), 2053, 2017 | 101 | 2017 |
Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery SH Chiou, D Tseng, A Reuben, V Mallajosyula, IS Molina, S Conley, ... Immunity 54 (3), 586-602. e8, 2021 | 95 | 2021 |
An in vivo multiplexed small-molecule screening platform BM Grüner, CJ Schulze, D Yang, D Ogasawara, MM Dix, ZN Rogers, ... Nature methods 13 (10), 883-889, 2016 | 65 | 2016 |
BLIMP1 induces transient metastatic heterogeneity in pancreatic cancer SH Chiou, VI Risca, GX Wang, D Yang, BM Grüner, AS Kathiria, RK Ma, ... Cancer discovery 7 (10), 1184-1199, 2017 | 61 | 2017 |
Obligate progression precedes lung adenocarcinoma dissemination DR Caswell, CH Chuang, D Yang, SH Chiou, S Cheemalavagu, ... Cancer discovery 4 (7), 781-789, 2014 | 56 | 2014 |
In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls W Jiang, JR Birtley, SC Hung, W Wang, SH Chiou, C Macaubas, ... Nature communications 10 (1), 5247, 2019 | 48 | 2019 |
Integration of high-risk human papillomavirus DNA correlates with HLA genotype aberration and reduced HLA class I molecule expression in human cervical carcinoma BC Sheu, SH Chiou, WC Chang, SN Chow, HH Lin, RJ Chen, SC Huang, ... Clinical Immunology 115 (3), 295-301, 2005 | 34 | 2005 |
Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance SH Chiou, M Dorsch, E Kusch, S Naranjo, MM Kozak, AC Koong, ... Scientific reports 8 (1), 14008, 2018 | 30 | 2018 |
Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis P Shahi, D Park, AC Pond, M Seethammagari, SH Chiou, K Cho, ... PloS one 7 (1), e30814, 2012 | 23 | 2012 |
Long-term skeletal outcomes of primary hyperparathyroidism patients after treatment with parathyroidectomy: a systematic review and meta-analysis L Zhang, X Liu, H Li Hormone and Metabolic Research 50 (03), 242-249, 2018 | 20 | 2018 |
Expression of inhibitory natural killer receptors on tumor-infiltrating CD8+ T lymphocyte lineage in human endometrial carcinoma WC Chang, SC Huang, PL Torng, DY Chang, WC Hsu, SH Chiou, ... International Journal of Gynecologic Cancer 15 (6), 2005 | 18 | 2005 |