Regulation of organismal proteostasis by transcellular chaperone signaling P van Oosten-Hawle, RS Porter, RI Morimoto Cell 153 (6), 1366-1378, 2013 | 207 | 2013 |
The middle domain of Hsp90 acts as a discriminator between different types of client proteins P Hawle, M Siepmann, A Harst, M Siderius, HP Reusch, WMJ Obermann Molecular and cellular biology, 2006 | 162 | 2006 |
A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function CPA Doherty, SM Ulamec, R Maya-Martinez, SC Good, J Makepeace, ... Nature structural & molecular biology 27 (3), 249-259, 2020 | 153 | 2020 |
Amyloid fibres: inert end-stage aggregates or key players in disease? KW Tipping, P van Oosten-Hawle, EW Hewitt, SE Radford Trends in biochemical sciences 40 (12), 719-727, 2015 | 118 | 2015 |
Organismal proteostasis: role of cell-nonautonomous regulation and transcellular chaperone signaling P van Oosten-Hawle, RI Morimoto Genes & development 28 (14), 1533-1543, 2014 | 101 | 2014 |
Cdc37p is required for stress-induced high-osmolarity glycerol and protein kinase C mitogen-activated protein kinase pathway functionality by interaction with Hog1p and Slt2p … P Hawle, D Horst, JP Bebelman, XX Yang, M Siderius, SM van der Vies Eukaryotic cell 6 (3), 521-532, 2007 | 78 | 2007 |
A PQM-1-mediated response triggers transcellular chaperone signaling and regulates organismal proteostasis D O’Brien, LM Jones, S Good, J Miles, MS Vijayabaskar, R Aston, ... Cell Reports 23 (13), 3905-3919, 2018 | 64 | 2018 |
Transcellular chaperone signaling: an organismal strategy for integrated cell stress responses P van Oosten-Hawle, RI Morimoto Journal of Experimental Biology 217 (1), 129-136, 2014 | 59 | 2014 |
Expanding the organismal proteostasis network: linking systemic stress signaling with the innate immune response J Miles, R Scherz-Shouval, P van Oosten-Hawle Trends in biochemical sciences 44 (11), 927-942, 2019 | 39 | 2019 |
Single residue modulators of amyloid formation in the N-terminal P1-region of α-synuclein SM Ulamec, R Maya-Martinez, EJ Byrd, KM Dewison, Y Xu, LF Willis, ... Nature communications 13 (1), 4986, 2022 | 27 | 2022 |
Regulation of cell-non-autonomous proteostasis in metazoans D O'Brien, P van Oosten-Hawle Essays in Biochemistry 60 (2), 133-142, 2016 | 23 | 2016 |
The intestine as a lifespan-and proteostasis-promoting signaling tissue F Hodge, V Bajuszova, P van Oosten-Hawle Frontiers in Aging 3, 897741, 2022 | 17 | 2022 |
Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease RE Lackie, J Marques-Lopes, VG Ostapchenko, S Good, WY Choy, ... Acta neuropathologica communications 8, 1-19, 2020 | 17 | 2020 |
Duplication of hsp-110 Is Implicated in Differential Success of Globodera Species under Climate Change LM Jones, S Eves-van den Akker, P van-Oosten Hawle, HJ Atkinson, ... Molecular Biology and Evolution 35 (10), 2401-2413, 2018 | 15 | 2018 |
Cdc37p is involved in osmoadaptation and controls high osmolarity-induced cross-talk via the MAP kinase Kss1p XX Yang, P Hawle, JP Bebelman, A Meenhuis, M Siderius, ... FEMS yeast research 7 (6), 796-807, 2007 | 14 | 2007 |
Tissue-specific RNAi tools to identify components for systemic stress signaling J Miles, P van Oosten-Hawle JoVE (Journal of Visualized Experiments), e61357, 2020 | 9 | 2020 |
Transcellular chaperone signaling is an intercellular stress-response distinct from the HSF-1–mediated heat shock response J Miles, S Townend, D Milonaitytė, W Smith, F Hodge, DR Westhead, ... PLoS Biology 21 (2), e3001605, 2023 | 8 | 2023 |
Exploiting inter-tissue stress signaling mechanisms to preserve organismal proteostasis during aging P van Oosten-Hawle Frontiers in Physiology 14, 1228490, 2023 | 7 | 2023 |
Redefining proteostasis transcription factors in organismal stress responses, development, metabolism, and health LM Jones, Y Chen, P van Oosten-Hawle Biological Chemistry 401 (9), 1005-1018, 2020 | 7 | 2020 |
Organismal roles of Hsp90 P van Oosten-Hawle Biomolecules 13 (2), 251, 2023 | 6 | 2023 |