Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression T Irifuku, S Doi, K Sasaki, T Doi, A Nakashima, T Ueno, K Yamada, ... Kidney International 89 (1), 147-157, 2016 | 112 | 2016 |
TGF-β promotes fibrosis after severe acute kidney injury by enhancing renal macrophage infiltration S Chung, JM Overstreet, Y Li, Y Wang, A Niu, S Wang, X Fan, K Sasaki, ... JCI insight 3 (21), 2018 | 105 | 2018 |
Inhibition of SET domain–containing lysine methyltransferase 7/9 ameliorates renal fibrosis K Sasaki, S Doi, A Nakashima, T Irifuku, K Yamada, K Kokoroishi, T Ueno, ... Journal of the American society of nephrology 27 (1), 203-215, 2016 | 97 | 2016 |
Podocyte EGFR inhibits autophagy through upregulation of rubicon in type 2 diabetic nephropathy Y Li, Y Pan, S Cao, K Sasaki, Y Wang, A Niu, X Fan, S Wang, MZ Zhang, ... Diabetes 70 (2), 562-576, 2021 | 64 | 2021 |
Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice MK Inoue, Y Matsunaga, Y Nakatsu, T Yamamotoya, K Ueda, ... Diabetology & metabolic syndrome 11, 1-11, 2019 | 60 | 2019 |
Deletion of myeloid interferon regulatory factor 4 (Irf4) in mouse model protects against kidney fibrosis after ischemic injury by decreased macrophage recruitment and activation K Sasaki, AS Terker, Y Pan, Z Li, S Cao, Y Wang, A Niu, S Wang, X Fan, ... Journal of the American Society of Nephrology 32 (5), 1037-1052, 2021 | 53 | 2021 |
Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16INK4a H Shimoda, S Doi, A Nakashima, K Sasaki, T Doi, T Masaki Kidney international 96 (5), 1162-1175, 2019 | 45 | 2019 |
Xanthine oxidase inhibitor febuxostat exerts an anti-inflammatory action and protects against diabetic nephropathy development in KK-Ay obese diabetic mice Y Mizuno, T Yamamotoya, Y Nakatsu, K Ueda, Y Matsunaga, MK Inoue, ... International Journal of Molecular Sciences 20 (19), 4680, 2019 | 35 | 2019 |
Inhibition of the H3K4 methyltransferase SET7/9 ameliorates peritoneal fibrosis R Tamura, S Doi, A Nakashima, K Sasaki, K Maeda, T Ueno, T Masaki PloS one 13 (5), e0196844, 2018 | 35 | 2018 |
A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-α and TGF-β1 pathways H Shima, K Sasaki, T Suzuki, C Mukawa, T Obara, Y Oba, A Matsuo, ... Scientific reports 7 (1), 1884, 2017 | 33 | 2017 |
The role of the EGF receptor in sex differences in kidney injury MZ Zhang, K Sasaki, Y Li, Z Li, Y Pan, G Jin, Y Wang, A Niu, S Wang, ... Journal of the american society of nephrology 30 (9), 1659-1673, 2019 | 32 | 2019 |
Deubiquitinase inhibitor PR-619 reduces Smad4 expression and suppresses renal fibrosis in mice with unilateral ureteral obstruction K Soji, S Doi, A Nakashima, K Sasaki, T Doi, T Masaki PLoS One 13 (8), e0202409, 2018 | 27 | 2018 |
Myeloid cyclooxygenase-2/prostaglandin E2/E-type prostanoid receptor 4 promotes transcription factor MafB-dependent inflammatory resolution in acute kidney injury Y Pan, S Cao, AS Terker, J Tang, K Sasaki, Y Wang, A Niu, W Luo, ... Kidney international 101 (1), 79-91, 2022 | 26 | 2022 |
microRNA-200c regulates KLOTHO expression in human kidney cells under oxidative stress K Morii, S Yamasaki, S Doi, T Irifuku, K Sasaki, T Doi, A Nakashima, ... PLoS One 14 (6), e0218468, 2019 | 24 | 2019 |
The xanthine oxidase inhibitor febuxostat suppresses the progression of IgA nephropathy, possibly via its anti-inflammatory and anti-fibrotic effects in the gddY mouse model MK Inoue, T Yamamotoya, Y Nakatsu, K Ueda, Y Inoue, Y Matsunaga, ... International Journal of Molecular Sciences 19 (12), 3967, 2018 | 21 | 2018 |
Klotho overexpression protects against renal aging along with suppression of transforming growth factor-β1 signaling pathways H Oishi, S Doi, A Nakashima, T Ike, Y Maeoka, K Sasaki, T Doi, T Masaki American Journal of Physiology-Renal Physiology 321 (6), F799-F811, 2021 | 17 | 2021 |
Linagliptin ameliorates methylglyoxal-induced peritoneal fibrosis in mice T Nagai, S Doi, A Nakashima, T Irifuku, K Sasaki, T Ueno, T Masaki PLoS One 11 (8), e0160993, 2016 | 15 | 2016 |
TGF-β1 promotes expression of fibrosis-related genes through the induction of histone variant H3. 3 and histone chaperone HIRA T Shindo, S Doi, A Nakashima, K Sasaki, K Arihiro, T Masaki Scientific reports 8 (1), 14060, 2018 | 14 | 2018 |
Activation of hypoxia-sensing pathways promotes renal ischemic preconditioning following myocardial infarction AS Terker, K Sasaki, JP Arroyo, A Niu, S Wang, X Fan, Y Zhang, ... American Journal of Physiology-Renal Physiology 320 (4), F569-F577, 2021 | 13 | 2021 |
Macrophage interferon regulatory factor 4 deletion ameliorates aristolochic acid nephropathy via reduced migration and increased apoptosis K Sasaki, AS Terker, J Tang, S Cao, JP Arroyo, A Niu, S Wang, X Fan, ... Jci insight 7 (4), 2022 | 11 | 2022 |