TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion H Seo, J Chen, E González-Avalos, D Samaniego-Castruita, A Das, ... Proceedings of the National Academy of Sciences 116 (25), 12410-12415, 2019 | 580 | 2019 |
BATF and IRF4 cooperate to counter exhaustion in tumor-infiltrating CAR T cells H Seo, E González-Avalos, W Zhang, P Ramchandani, C Yang, CWJ Lio, ... Nature immunology 22 (8), 983-995, 2021 | 193 | 2021 |
Acute loss of TET function results in aggressive myeloid cancer in mice J An, E González-Avalos, A Chawla, M Jeong, IF López-Moyado, W Li, ... Nature communications 6 (1), 10071, 2015 | 186 | 2015 |
Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility CW Lio, J Zhang, E González-Avalos, PG Hogan, X Chang, A Rao Elife 5, e18290, 2016 | 164 | 2016 |
TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells A Tsagaratou, E González-Avalos, S Rautio, JP Scott-Browne, S Togher, ... Nature immunology 18 (1), 45-53, 2017 | 131 | 2017 |
TET enzymes augment activation-induced deaminase (AID) expression via 5-hydroxymethylcytosine modifications at the Aicda superenhancer CWJ Lio, V Shukla, D Samaniego-Castruita, E González-Avalos, ... Science immunology 4 (34), eaau7523, 2019 | 78 | 2019 |
Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells A Onodera, E González-Avalos, CWJ Lio, RO Georges, A Bellacosa, ... Genome Biology 22 (1), 186, 2021 | 48 | 2021 |
TET deficiency perturbs mature B cell homeostasis and promotes oncogenesis associated with accumulation of G-quadruplex and R-loop structures V Shukla, D Samaniego-Castruita, Z Dong, E González-Avalos, Q Yan, ... Nature immunology 23 (1), 99-108, 2022 | 44 | 2022 |
Targeting the NFAT: AP-1 transcriptional complex on DNA with a small-molecule inhibitor GP Mognol, E González-Avalos, S Ghosh, R Spreafico, A Gudlur, A Rao, ... Proceedings of the National Academy of Sciences 116 (20), 9959-9968, 2019 | 42 | 2019 |
Whole‐genome analysis of TET dioxygenase function in regulatory T cells X Yue, D Samaniego‐Castruita, E González‐Avalos, X Li, BG Barwick, ... EMBO reports 22 (8), e52716, 2021 | 26 | 2021 |
Epigenetic remodeling by vitamin C potentiates plasma cell differentiation HY Chen, A Almonte-Loya, FY Lay, M Hsu, E Johnson, ... Elife 11, e73754, 2022 | 12 | 2022 |
Spatiotemporal resolution of germinal center Tfh cell differentiation and divergence from central memory CD4+ T cell fate F Zhu, RJ McMonigle, AR Schroeder, X Xia, D Figge, BD Greer, ... Nature communications 14 (1), 3611, 2023 | 7 | 2023 |
Strategies for network GWAS evaluated using classroom crowd science SH Fong, DE Carlin, K Ozturk, N Arang, B Bao, H Bennett, X Cai, K Chau, ... Cell systems 8 (4), 275-280, 2019 | 6 | 2019 |
5-Azacytidine transiently restores dysregulated erythroid differentiation gene expression in TET2-deficient erythroleukemia cells BM Reilly, T Luger, S Park, CWJ Lio, E González-Avalos, EC Wheeler, ... Molecular Cancer Research 19 (3), 451-464, 2021 | 5 | 2021 |
Disruption of TOX transcription factors enhances CAR T cells function in solid tumors H Seo, J Chen, EG Avalos, DS Castruita, IL Moyado, CJ Wu, A Das, LF Lu, ... The Journal of Immunology 202 (1_Supplement), 134.3-134.3, 2019 | 2 | 2019 |
TET enzymes augment AID expression via 5hmC modifications at the Aicda superenhancer CWJ Lio, V Shukla, D Samaniego-Castruita, E González-Avalos, ... bioRxiv, 438531, 2018 | 2 | 2018 |
Epigenetic remodeling by vitamin C potentiates the differentiation of mouse and human plasma cells HY Chen, A Alamonte-Loya, FY Lay, E Johnson, E Gonzalez-Avalos, ... bioRxiv, 2021.09. 15.460473, 2021 | 1 | 2021 |
Predicting gene expression state and prioritizing putative enhancers using 5hmC signal E Gonzalez-Avalos, A Onodera, D Samaniego-Castruita, A Rao, F Ay Genome Biology 25 (1), 142, 2024 | | 2024 |
The divergence of PD-1+ CXCR5+ CD4+ T cell differentiation and stage-specific regulation of GC-Tfh cells F Zhu, RJ McMonigle, AR Schroeder, X Xia, D Figge, BD Greer, ... The Journal of Immunology 210 (1_Supplement), 76.11-76.11, 2023 | | 2023 |
Epigenetic Remodeling by Vitamin C Potentiates the Differentiation of Mouse and Human Plasma Cells CWJ Lio, HY Chen, A Almonte-Loya, FY Lay, E Johnson, ... The Journal of Immunology 208 (1_Supplement), 168.09-168.09, 2022 | | 2022 |