Dissecting virulence: systematic and functional analyses of a pathogenicity island W Deng, JL Puente, S Gruenheid, Y Li, BA Vallance, A Vázquez, J Barba, ... Proceedings of the National Academy of Sciences 101 (10), 3597-3602, 2004 | 746 | 2004 |
Assembly, structure, function and regulation of type III secretion systems W Deng, NC Marshall, JL Rowland, JM McCoy, LJ Worrall, AS Santos, ... Nature Reviews Microbiology 15 (6), 323-337, 2017 | 547 | 2017 |
Locus of enterocyte effacement from Citrobacter rodentium: sequence analysis and evidence for horizontal transfer among attaching and effacing pathogens W Deng, Y Li, BA Vallance, BB Finlay Infection and Immunity 69 (10), 6323, 2001 | 294 | 2001 |
Identification and characterization of NleA, a non‐LEE‐encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157: H7 S Gruenheid, I Sekirov, NA Thomas, W Deng, P O'Donnell, D Goode, Y Li, ... Molecular Microbiology 51 (5), 1233-1249, 2004 | 278 | 2004 |
A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system T Spreter, CK Yip, S Sanowar, I André, TG Kimbrough, M Vuckovic, ... Nature Structural & Molecular Biology 16 (5), 468-476, 2009 | 239 | 2009 |
Attaching and effacing pathogen‐induced tight junction disruption in vivo JA Guttman, Y Li, ME Wickham, W Deng, AW Vogl, BB Finlay Cellular Microbiology 8 (4), 634-645, 2006 | 232 | 2006 |
Host susceptibility to the attaching and effacing bacterial pathogen Citrobacter rodentium BA Vallance, W Deng, K Jacobson, BB Finlay Infection and Immunity 71 (6), 3443, 2003 | 232 | 2003 |
Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in mice W Deng, BA Vallance, Y Li, JL Puente, BB Finlay Molecular Microbiology 48 (1), 95-115, 2003 | 228 | 2003 |
Regulation of type III secretion hierarchy of translocators and effectors in attaching and effacing bacterial pathogens W Deng, Y Li, PR Hardwidge, EA Frey, RA Pfuetzner, S Lee, S Gruenheid, ... Infection and Immunity 73 (4), 2135, 2005 | 217 | 2005 |
Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice MA Khan, C Ma, LA Knodler, Y Valdez, CM Rosenberger, W Deng, ... Infection and Immunity 74 (5), 2522, 2006 | 197 | 2006 |
A positive regulatory loop controls expression of the locus of enterocyte effacement-encoded regulators Ler and GrlA J Barba, VH Bustamante, MA Flores-Valdez, W Deng, BB Finlay, ... Journal of Bacteriology 187 (23), 7918, 2005 | 185 | 2005 |
Structural analysis of a prototypical ATPase from the type III secretion system R Zarivach, M Vuckovic, W Deng, BB Finlay, NCJ Strynadka Nature Structural & Molecular Biology 14 (2), 131-137, 2007 | 182 | 2007 |
Bacterial effector binding to ribosomal protein s3 subverts NF-κB function X Gao, F Wan, K Mateo, E Callegari, D Wang, W Deng, J Puente, F Li, ... PLoS Pathogens 5 (12), e1000708, 2009 | 180 | 2009 |
Mice lacking T and B lymphocytes develop transient colitis and crypt hyperplasia yet suffer impaired bacterial clearance during Citrobacter rodentium infection BA Vallance, W Deng, LA Knodler, BB Finlay Infection and Immunity 70 (4), 2070, 2002 | 174 | 2002 |
Aquaporins contribute to diarrhoea caused by attaching and effacing bacterial pathogens JA Guttman, FN Samji, Y Li, W Deng, A Lin, BB Finlay Cellular Microbiology 9 (1), 131-141, 2007 | 166 | 2007 |
Role of inflammasomes in host defense against Citrobacter rodentium infection Z Liu, MH Zaki, P Vogel, P Gurung, BB Finlay, W Deng, M Lamkanfi, ... Journal of Biological chemistry 287 (20), 16955-16964, 2012 | 164 | 2012 |
Agrobacterium VirD2 protein interacts with plant host cyclophilins W Deng, L Chen, DW Wood, T Metcalfe, X Liang, MP Gordon, L Comai, ... Proceedings of the National Academy of Sciences 95 (12), 7040-7045, 1998 | 163 | 1998 |
Citrobacter rodentium infection causes both mitochondrial dysfunction and intestinal epithelial barrier disruption in vivo: role of mitochondrial associated protein (Map) C Ma, ME Wickham, JA Guttman, W Deng, J Walker, KL Madsen, ... Cellular Microbiology 8 (10), 1669-1686, 2006 | 159 | 2006 |
Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS R Zarivach, W Deng, M Vuckovic, HB Felise, HV Nguyen, SI Miller, ... Nature 453 (7191), 124-127, 2008 | 158 | 2008 |
Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body LJ Worrall, C Hong, M Vuckovic, W Deng, JRC Bergeron, DD Majewski, ... Nature 540 (7634), 597-601, 2016 | 146 | 2016 |