Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation T Raisch, CT Chang, Y Levdansky, S Muthukumar, S Raunser, E Valkov Nature communications 10 (1), 3173, 2019 | 84 | 2019 |
Pseudouridine-modified tRNA fragments repress aberrant protein synthesis and predict leukaemic progression in myelodysplastic syndrome N Guzzi, S Muthukumar, M Cieśla, G Todisco, PCT Ngoc, M Madej, ... Nature cell biology, 1-8, 2022 | 58 | 2022 |
Structure of the Dcp2–Dcp1 mRNA-decapping complex in the activated conformation E Valkov, S Muthukumar, CT Chang, S Jonas, O Weichenrieder, ... Nature structural & molecular biology 23 (6), 574, 2016 | 58 | 2016 |
Mechanism of chiral proofreading during translation of the genetic code S Ahmad, SB Routh, V Kamarthapu, J Chalissery, S Muthukumar, ... Elife 2, e01519, 2013 | 46 | 2013 |
Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer M Cieśla, PCT Ngoc, E Cordero, ÁS Martinez, M Morsing, S Muthukumar, ... Molecular Cell 81 (7), 1453-1468. e12, 2021 | 41 | 2021 |
The NBDY microprotein regulates cellular RNA decapping Z Na, Y Luo, JA Schofield, S Smelyansky, A Khitun, S Muthukumar, ... Biochemistry 59 (42), 4131-4142, 2020 | 35 | 2020 |
Protective effect of ellagic acid (EA) on micronucleus formation induced by N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) in mammalian cells, in in vitro assays and in vivo A Berni, MR Grossi, G Pepe, S Filippi, S Muthukumar, C Papeschi, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 746 (1 …, 2012 | 35 | 2012 |
A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5′–3′ messenger RNA decay CT Chang, S Muthukumar, R Weber, Y Levdansky, Y Chen, D Bhandari, ... Nucleic acids research, 2019 | 32 | 2019 |
Specificity and catalysis hardwired at the RNA–protein interface in a translational proofreading enzyme S Ahmad, S Muthukumar, SK Kuncha, SB Routh, ASK Yerabham, ... Nature communications 6, 7552, 2015 | 24 | 2015 |
The small Cajal body-specific RNA 15 (SCARNA15) directs p53 and redox homeostasis via selective splicing in cancer cells G Beneventi, R Munita, P Cao Thi Ngoc, M Madej, M Cieśla, ... NAR cancer 3 (3), zcab026, 2021 | 20 | 2021 |
m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis M Cieśla, PCT Ngoc, S Muthukumar, G Todisco, M Madej, H Fritz, ... Molecular Cell 83 (7), 1165-1179. e11, 2023 | 11 | 2023 |
Ribosomal biogenesis regulator DIMT1 controls β-cell protein synthesis, mitochondrial function, and insulin secretion G Verma, A Bowen, S Gheibi, A Hamilton, S Muthukumar, LR Cataldo, ... Journal of Biological Chemistry 298 (3), 2022 | 11 | 2022 |
Roles and regulation of tRNA-derived small RNAs in animals S Muthukumar, CT Li, RJ Liu, C Bellodi Nature Reviews Molecular Cell Biology, 1-20, 2024 | 6 | 2024 |
A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia M Eldeeb, O Yuan, N Guzzi, PCT Ngoc, A Konturek-Ciesla, TA Kristiansen, ... Cell Reports 42 (2), 2023 | 6 | 2023 |
Molecular mechanisms of messenger RNA decapping S Muthukumar Universität Tübingen, 2021 | | 2021 |