Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening M Smilkstein, N Sriwilaijaroen, JX Kelly, P Wilairat, M Riscoe Antimicrobial agents and chemotherapy 48 (5), 1803-1806, 2004 | 1271 | 2004 |
Chemical genetics of Plasmodium falciparum WA Guiguemde, AA Shelat, D Bouck, S Duffy, GJ Crowther, PH Davis, ... Nature 465 (7296), 311-315, 2010 | 649 | 2010 |
Quinolone-3-diarylethers: a new class of antimalarial drug A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ... Science translational medicine 5 (177), 177ra37-177ra37, 2013 | 249 | 2013 |
Discovery of dual function acridones as a new antimalarial chemotype JX Kelly, MJ Smilkstein, R Brun, S Wittlin, RA Cooper, KD Lane, ... Nature 459 (7244), 270-273, 2009 | 212 | 2009 |
Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis JS Doggett, A Nilsen, I Forquer, KW Wegmann, L Jones-Brando, ... Proceedings of the National Academy of Sciences 109 (39), 15936-15941, 2012 | 197 | 2012 |
Antimalarial quinolones: synthesis, potency, and mechanistic studies RW Winter, JX Kelly, MJ Smilkstein, R Dodean, D Hinrichs, MK Riscoe Experimental parasitology 118 (4), 487-497, 2008 | 193 | 2008 |
A Chloroquine-like Molecule Designed to Reverse Resistance in Plasmodium falciparum SJ Burgess, A Selzer, JX Kelly, MJ Smilkstein, MK Riscoe, DH Peyton Journal of medicinal chemistry 49 (18), 5623-5625, 2006 | 192 | 2006 |
Xanthones as antimalarial agents; studies of a possible mode of action MV Ignatushchenko, RW Winter, HP Bächinger, DJ Hinrichs, MK Riscoe FEBS letters 409 (1), 67-73, 1997 | 156 | 1997 |
Evaluation and lead optimization of anti-malarial acridones RW Winter, JX Kelly, MJ Smilkstein, R Dodean, GC Bagby, RK Rathbun, ... Experimental parasitology 114 (1), 47-56, 2006 | 140 | 2006 |
Xanthones as antimalarial agents: discovery, mode of action, and optimization M Riscoe, JX Kelly, R Winter Current medicinal chemistry 12 (21), 2539-2549, 2005 | 135 | 2005 |
Discovery, Synthesis, and Optimization of Antimalarial 4(1H)-Quinolone-3-Diarylethers A Nilsen, GP Miley, IP Forquer, MW Mather, K Katneni, Y Li, S Pou, ... Journal of medicinal chemistry 57 (9), 3818-3834, 2014 | 126 | 2014 |
Optimization of endochin-like quinolones for antimalarial activity R Winter, JX Kelly, MJ Smilkstein, D Hinrichs, DR Koop, MK Riscoe Experimental parasitology 127 (2), 545-551, 2011 | 109 | 2011 |
Structure of E. coli 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase reveals similarity to the purine nucleoside phosphorylases JE Lee, KA Cornell, MK Riscoe, PL Howell Structure 9 (10), 941-953, 2001 | 104 | 2001 |
Characterization of RecombinantEschericha coli5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase: Analysis of Enzymatic Activity and Substrate Specificity KA Cornell, WE Swarts, RD Barry, MK Riscoe Biochemical and biophysical research communications 228 (3), 724-732, 1996 | 97 | 1996 |
Xanthones as antimalarial agents: stage specificity. MV Ignatushchenko, RW Winter, M Riscoe The American journal of tropical medicine and hygiene 62 (1), 77-81, 2000 | 94 | 2000 |
Structural Rationale for the Affinity of Pico-and Femtomolar Transition State Analogues of Escherichia coli 5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase*♦ JE Lee, V Singh, GB Evans, PC Tyler, RH Furneaux, KA Cornell, ... Journal of Biological Chemistry 280 (18), 18274-18282, 2005 | 93 | 2005 |
Arginase is essential for survival of Leishmania donovani promastigotes but not intracellular amastigotes JM Boitz, CA Gilroy, TD Olenyik, D Paradis, J Perdeh, K Dearman, ... Infection and immunity 85 (1), 10.1128/iai. 00554-16, 2017 | 88 | 2017 |
Potentiation of the antimalarial agent rufigallol RW Winter, KA Cornell, LL Johnson, M Ignatushchenko, DJ Hinrichs, ... Antimicrobial agents and chemotherapy 40 (6), 1408-1411, 1996 | 88 | 1996 |
Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone LA Lawres, A Garg, V Kumar, I Bruzual, IP Forquer, I Renard, AZ Virji, ... Journal of Experimental Medicine 213 (7), 1307-1318, 2016 | 85 | 2016 |
α lipoic acid inhibits human T‐cell migration: Implications for multiple sclerosis GH Marracci, GP McKeon, WE Marquardt, RW Winter, MK Riscoe, ... Journal of neuroscience research 78 (3), 362-370, 2004 | 79 | 2004 |