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Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study BP Scicluna, LA Van Vught, AH Zwinderman, MA Wiewel, EE Davenport, ... The Lancet Respiratory Medicine 5 (10), 816-826, 2017 | 436 | 2017 |
Factors influencing success of clinical genome sequencing across a broad spectrum of disorders JC Taylor, HC Martin, S Lise, J Broxholme, JB Cazier, A Rimmer, ... Nature genetics 47 (7), 717-726, 2015 | 414 | 2015 |
Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study A Rautanen, TC Mills, AC Gordon, P Hutton, M Steffens, R Nuamah, ... The Lancet Respiratory Medicine 3 (1), 53-60, 2015 | 212 | 2015 |
Shared and distinct aspects of the sepsis transcriptomic response to fecal peritonitis and pneumonia KL Burnham, EE Davenport, J Radhakrishnan, P Humburg, AC Gordon, ... American journal of respiratory and critical care medicine 196 (3), 328-339, 2017 | 191 | 2017 |
A community approach to mortality prediction in sepsis via gene expression analysis TE Sweeney, TM Perumal, R Henao, M Nichols, JA Howrylak, AM Choi, ... Nature communications 9 (1), 694, 2018 | 190 | 2018 |
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity DJ Ahern, Z Ai, M Ainsworth, C Allan, A Allcock, B Angus, MA Ansari, ... Cell 185 (5), 916-938. e58, 2022 | 171 | 2022 |
Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency disorders PA van Schouwenburg, EE Davenport, AK Kienzler, I Marwah, B Wright, ... Clinical immunology 160 (2), 301-314, 2015 | 116 | 2015 |
Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis AJ Kwok, A Allcock, RC Ferreira, E Cano-Gamez, M Smee, KL Burnham, ... Nature Immunology 24 (5), 767-779, 2023 | 63 | 2023 |
IMPACT: genomic annotation of cell-state-specific regulatory elements inferred from the epigenome of bound transcription factors T Amariuta, Y Luo, S Gazal, EE Davenport, B van de Geijn, K Ishigaki, ... The American Journal of Human Genetics 104 (5), 879-895, 2019 | 57 | 2019 |
Transcriptomic profiling facilitates classification of response to influenza challenge EE Davenport, RD Antrobus, PJ Lillie, S Gilbert, JC Knight Journal of molecular medicine 93, 105-114, 2015 | 46 | 2015 |
An atlas of genetic scores to predict multi-omic traits Y Xu, SC Ritchie, Y Liang, PRHJ Timmers, M Pietzner, L Lannelongue, ... Nature 616 (7955), 123-131, 2023 | 41 | 2023 |
Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial EE Davenport, T Amariuta, M Gutierrez-Arcelus, K Slowikowski, ... Genome biology 19, 1-15, 2018 | 39 | 2018 |
Chronic mucocutaneous candidiasis: characterization of a family with STAT-1 gain-of-function and development of an ex-vivo assay for Th17 deficiency of … F Dhalla, H Fox, EE Davenport, R Sadler, C Anzilotti, ... Clinical & Experimental Immunology 184 (2), 216-227, 2016 | 37 | 2016 |
An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression E Cano-Gamez, KL Burnham, C Goh, A Allcock, ZH Malick, L Overend, ... Science translational medicine 14 (669), eabq4433, 2022 | 31 | 2022 |
Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19 AK Maher, KL Burnham, EM Jones, MMH Tan, RC Saputil, L Baillon, ... Nature Communications 13 (1), 7947, 2022 | 27 | 2022 |
Epstein-Barr virus reactivation in sepsis due to community-acquired pneumonia is associated with increased morbidity and an immunosuppressed host transcriptomic endotype C Goh, KL Burnham, MA Ansari, M de Cesare, T Golubchik, P Hutton, ... Scientific Reports 10 (1), 9838, 2020 | 18 | 2020 |
A common haplotype of the TNF receptor 2 gene modulates endotoxin tolerance BP Fairfax, EE Davenport, S Makino, AVS Hill, FO Vannberg, JC Knight The Journal of Immunology 186 (5), 3058-3065, 2011 | 18 | 2011 |
Interactions between genome‐wide genetic factors and smoking influencing risk of systemic lupus erythematosus J Cui, S Raychaudhuri, EW Karlson, C Speyer, S Malspeis, H Guan, ... Arthritis & rheumatology 72 (11), 1863-1871, 2020 | 17 | 2020 |
Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19 CP Kotanidis, C Xie, D Alexander, JCL Rodrigues, K Burnham, A Mentzer, ... The Lancet Digital Health 4 (10), e705-e716, 2022 | 15 | 2022 |