Oligoribonuclease is the primary degradative enzyme for pGpG in Pseudomonas aeruginosa that is required for cyclic-di-GMP turnover MW Orr, GP Donaldson, GB Severin, J Wang, HO Sintim, CM Waters, ... Proceedings of the National Academy of Sciences 112 (36), E5048-E5057, 2015 | 157 | 2015 |
Direct activation of a phospholipase by cyclic GMP-AMP in El Tor Vibrio cholerae GB Severin, MS Ramliden, LA Hawver, K Wang, ME Pell, AK Kieninger, ... Proceedings of the National Academy of Sciences 115 (26), E6048-E6055, 2018 | 131 | 2018 |
The Vibrio cholerae diguanylate cyclase VCA0965 has an AGDEF active site and synthesizes cyclic di-GMP JL Hunter, GB Severin, BJ Koestler, CM Waters BMC microbiology 14, 1-10, 2014 | 47 | 2014 |
Phage defence by deaminase-mediated depletion of deoxynucleotides in bacteria BY Hsueh, GB Severin, CA Elg, EJ Waldron, A Kant, AJ Wessel, JA Dover, ... Nature microbiology 7 (8), 1210-1220, 2022 | 44 | 2022 |
Cyclic di-GMP regulates TfoY in Vibrio cholerae to control motility by both transcriptional and posttranscriptional mechanisms BR Pursley, MM Maiden, ML Hsieh, NL Fernandez, GB Severin, ... Journal of bacteriology 200 (7), 10.1128/jb. 00578-17, 2018 | 41 | 2018 |
Surface sensing stimulates cellular differentiation in Caulobacter crescentus RA Snyder, CK Ellison, GB Severin, GB Whitfield, CM Waters, YV Brun Proceedings of the National Academy of Sciences 117 (30), 17984-17991, 2020 | 34 | 2020 |
Cyclic di-GMP and VpsR induce the expression of type II secretion in Vibrio cholerae RE Sloup, AE Konal, GB Severin, ML Korir, MM Bagdasarian, ... Journal of bacteriology 199 (19), 10.1128/jb. 00106-17, 2017 | 34 | 2017 |
Feedback regulation of Caulobacter crescentus holdfast synthesis by flagellum assembly via the holdfast inhibitor HfiA C Berne, CK Ellison, R Agarwal, GB Severin, A Fiebig, RI Morton III, ... Molecular microbiology 110 (2), 219-238, 2018 | 33 | 2018 |
A feed‐forward signalling circuit controls bacterial virulence through linking cyclic di‐GMP and two mechanistically distinct sRNAs, ArcZ and RsmB X Yuan, Q Zeng, D Khokhani, F Tian, GB Severin, CM Waters, J Xu, ... Environmental microbiology 21 (8), 2755-2771, 2019 | 30 | 2019 |
A subset of exoribonucleases serve as degradative enzymes for pGpG in c-di-GMP signaling MW Orr, CA Weiss, GB Severin, H Turdiev, SK Kim, A Turdiev, K Liu, ... Journal of bacteriology 200 (24), 10.1128/jb. 00300-18, 2018 | 29 | 2018 |
Homeostasis of second messenger cyclic-di-AMP is critical for cyanobacterial fitness and acclimation to abiotic stress M Agostoni, AR Logan-Jackson, ER Heinz, GB Severin, EL Bruger, ... Frontiers in Microbiology 9, 1121, 2018 | 29 | 2018 |
Under elevated c-di-GMP in Escherichia coli, YcgR alters flagellar motor bias and speed sequentially, with additional negative control of the flagellar regulon via the adaptor … V Nieto, JD Partridge, GB Severin, RZ Lai, CM Waters, JS Parkinson, ... Journal of Bacteriology 202 (1), 10.1128/jb. 00578-19, 2019 | 26 | 2019 |
The Vc2 cyclic di-GMP-dependent riboswitch of Vibrio cholerae regulates expression of an upstream putative small RNA by controlling RNA stability BR Pursley, NL Fernandez, GB Severin, CM Waters Journal of bacteriology 201 (21), 10.1128/jb. 00293-19, 2019 | 17 | 2019 |
The diguanylate cyclase GcpA inhibits the production of pectate lyases via the H‐NS protein and RsmB regulatory RNA in Dickeya dadantii X Yuan, F Tian, C He, GB Severin, CM Waters, Q Zeng, F Liu, CH Yang Molecular plant pathology 19 (8), 1873-1886, 2018 | 17 | 2018 |
A broadly conserved deoxycytidine deaminase protects bacteria from phage infection GB Severin, BY Hsueh, CA Elg, JA Dover, CR Rhoades, AJ Wessel, ... Biorxiv, 2021.03. 31.437871, 2021 | 12 | 2021 |
Tricarboxylic acid (TCA) cycle enzymes and intermediates modulate intracellular cyclic di-GMP levels and the production of plant cell wall–degrading enzymes in soft rot … X Yuan, Q Zeng, J Xu, GB Severin, X Zhou, CM Waters, GW Sundin, ... Molecular Plant-Microbe Interactions 33 (2), 296-307, 2020 | 12 | 2020 |
Activation of a Vibrio cholerae CBASS anti-phage system by quorum sensing and folate depletion GB Severin, MS Ramliden, KC Ford, AJ Van Alst, R Sanath-Kumar, ... Mbio 14 (5), e00875-23, 2023 | 10 | 2023 |
Shigella flexneri diguanylate cyclases regulate virulence R Ojha, AA Dittmar, GB Severin, BJ Koestler Journal of bacteriology 203 (23), 10.1128/jb. 00242-21, 2021 | 10 | 2021 |
The ADP-heptose biosynthesis enzyme GmhB is a conserved Gram-negative bacteremia fitness factor CL Holmes, SN Smith, SJ Gurczynski, GB Severin, LV Unverdorben, ... Infection and Immunity 90 (7), e00224-22, 2022 | 9 | 2022 |
Spectrophotometric and mass spectroscopic methods for the quantification and kinetic evaluation of in vitro c-di-GMP synthesis GB Severin, CM Waters c-di-GMP Signaling: Methods and Protocols, 71-84, 2017 | 7 | 2017 |