| An ID2-dependent mechanism for VHL inactivation in cancer SB Lee, V Frattini, M Bansal, AM Castano, D Sherman, K Hutchinson, ... Nature 529 (7585), 172-177, 2016 | 130 | 2016 |
| Targeting SLC transporters: small molecules as modulators and therapeutic opportunities A Schlessinger, N Zatorski, K Hutchinson, C Colas Trends in Biochemical Sciences 48 (9), 801-814, 2023 | 32 | 2023 |
| Functional genomics of OCTN2 variants informs protein-specific variant effect predictor for Carnitine Transporter Deficiency ML Koleske, G McInnes, JEH Brown, N Thomas, K Hutchinson, MY Chin, ... Proceedings of the National Academy of Sciences 119 (46), e2210247119, 2022 | 17 | 2022 |
| Conserved allosteric inhibition mechanism in SLC1 transporters Y Dong, J Wang, RA Garibsingh, K Hutchinson, Y Shi, G Eisenberg, X Yu, ... Elife 12, e83464, 2023 | 15 | 2023 |
| Substrate binding and inhibition of the anion exchanger 1 transporter MJ Capper, S Yang, AC Stone, S Vatansever, G Zilberg, YK Mathiharan, ... Nature structural & molecular biology 30 (10), 1495-1504, 2023 | 12 | 2023 |
| Antitumor T-cell homeostatic activation is uncoupled from homeostatic inhibition by checkpoint blockade N Marshall, K Hutchinson, TU Marron, M Aleynick, L Hammerich, ... Cancer discovery 9 (11), 1520-1537, 2019 | 12 | 2019 |
| The Effects of Prodrug Size and a Carbonyl Linker on l‐Type Amino Acid Transporter 1‐Targeted Cellular and Brain Uptake B Venteicher, K Merklin, HX Ngo, HC Chien, K Hutchinson, J Campbell, ... ChemMedChem 16 (5), 869-880, 2021 | 7 | 2021 |
| Haploinsufficiency underlies the neurodevelopmental consequences of SLC6A1 variants DB Silva, M Trinidad, A Ljungdahl, JL Revalde, GY Berguig, W Wallace, ... The American Journal of Human Genetics 111 (6), 1222-1238, 2024 | 6 | 2024 |
| Alanine serine cysteine transporter (ASCT) substrate binding site properties probed with hydroxyhomoserine esters E Ndaru, L Zielewicz, Y Shi, K Hutchinson, RAA Garibsingh, ... Journal of physical organic chemistry 35 (11), e4347, 2022 | 5 | 2022 |
| Describing inhibitor specificity for the amino acid transporter LAT1 from metainference simulations K Hutchinson, DB Silva, J Bohlke, C Clausen, AA Thomas, M Bonomi, ... Biophysical Journal 121 (23), 4476-4491, 2022 | 4 | 2022 |
| Comprehensive Characterization of LAT1 Cholesterol-Binding Sites K Hutchinson, A Schlessinger Journal of Chemical Theory and Computation 20 (8), 3349-3358, 2024 | 3 | 2024 |
| Mechanisms of Cholesterol Binding to LAT1 K Hutchinson, A Schlessinger bioRxiv, 2024.01. 02.573920, 2024 | | 2024 |
| Rational Ligand Discovery for Solute Carrier Transporters Using Computational Approaches KK Hutchinson Icahn School of Medicine at Mount Sinai, 2023 | | 2023 |
| Haploinsufficiency underlies the neurodevelopmental consequences ofSLC6A1/GAT-1 variants DB Silva, M Trinidad, A Ljungdahl, JL Revalde, GY Berguig, W Wallace, ... | | 2022 |
| Ligand discovery for LAT1 with molecular dynamics simulation and virtual screening KK Hutchinson, DB Silva, H Ngo, A Schlessinger, K Giacomini, A Thomas Biophysical Journal 121 (3), 8a, 2022 | | 2022 |
