Stowaways in the cargo: Contaminating nucleic acids in rAAV preparations for gene therapy. MA Brimble, SM Winston, AM Davidoff Molecular Therapy, 2023 | 13 | 2023 |
Preventing packaging of translatable P5-associated DNA contaminants in recombinant AAV vector preps MA Brimble, PH Cheng, SM Winston, IL Reeves, A Souquette, Y Spence, ... Molecular Therapy-Methods & Clinical Development 24, 280-291, 2022 | 12 | 2022 |
Role of the histone variant H2A. Z. 1 in memory, transcription, and alternative splicing is mediated by lysine modification A Reda, LA Hategan, TAB McLean, SD Creighton, JQ Luo, SES Chen, ... Neuropsychopharmacology, 1-11, 2024 | 2 | 2024 |
Pre-Existing Immunity to a Nucleic Acid Contaminant-Derived Antigen Mediates Transaminitis and Resultant Diminished Transgene Expression in a Mouse Model of Hepatic Recombinant … MA Brimble, CL Morton, SM Winston, IL Reeves, Y Spence, PH Cheng, ... Human Gene Therapy, 2024 | 1 | 2024 |
Non-encapsidated miRNA contaminants found in AAV preparations MA Brimble, SM Winston Molecular Therapy Methods & Clinical Development 32 (4), 2024 | | 2024 |
rAAV expressing a COBRA-designed influenza hemagglutinin generates a protective and durable adaptive immune response with a single dose KB Wiggins, SM Winston, IL Reeves, J Gaevert, Y Spence, MA Brimble, ... Journal of Virology 98 (8), e00781-24, 2024 | | 2024 |
The role of the m6A/m demethylase FTO in memory is both task and sex-dependent in mice AM Leonetti, IR Galluzzo, TAD McLean, G Stefanelli, F Ramnaraign, ... Neurobiology of Learning and Memory 210, 107903, 2024 | | 2024 |
Transcription, Translation, and Immunogenic Potential of P5-Associated rAAV Contaminants Post-Infection MA Brimble, PH Cheng, SM Winston, IL Reeves, A Souquette, Y Spence, ... MOLECULAR THERAPY 30 (4), 204-204, 2022 | | 2022 |
Strategies for multi-gene editing and reduction of translocations with CRISPR-Cpf1 in T cells for the development of improved cell therapies JA Zuris, A Bothmer, R Viswanathan, HS Abdulkerim, K Gareau, ... MOLECULAR THERAPY 27 (4), 105-106, 2019 | | 2019 |
Highly Efficient Single and Multi-gene Knockout with CRISPR-Cpf1 in T Cells for the Development of Improved Cell Therapies JA Zuris, R Viswanathan, KI Loveluck, TM Swartjes, MS Chin, JW Fang, ... HUMAN GENE THERAPY 29 (12), A103-A103, 2018 | | 2018 |
Maternal Effects of Aseptic and Septic Injury on Embryonic Larval Gene Expression in the Tobacco Hornworm, Manduca Sexta W Smith, T Gelaf-Romer, S Renteria, A Thwin, B Noonan, P Anderson, ... Intermountain Journal of Sciences 24 (3-4 December), 181-181, 2018 | | 2018 |
Maternal effects of aseptic and septic injury on embryonic and larval phenotype and gene expression in the tobacco hornworm, Manduca sexta W Smith, B Noonan, M Zaman, S Winston, AK Thwin, N Hays, ... Entomology 2017, 2017 | | 2017 |