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Molecular regulation of cardiac hypertrophy SP Barry, SM Davidson, PA Townsend The international journal of biochemistry & cell biology 40 (10), 2023-2039, 2008 | 437 | 2008 |
Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury L Valentim, KM Laurence, PA Townsend, CJ Carroll, S Soond, ... Journal of molecular and cellular cardiology 40 (6), 846-852, 2006 | 370 | 2006 |
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction DV Conti, BF Darst, LC Moss, EJ Saunders, X Sheng, A Chou, ... Nature genetics 53 (1), 65-75, 2021 | 337 | 2021 |
STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis PA Townsend, TM Scarabelli, SM Davidson, RA Knight, DS Latchman, ... Journal of Biological Chemistry 279 (7), 5811-5820, 2004 | 316 | 2004 |
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing P Galanos, K Vougas, D Walter, A Polyzos, A Maya-Mendoza, ... Nature cell biology 18 (7), 777-789, 2016 | 285 | 2016 |
Epigallocatechin‐3‐gallate inhibits STAT‐1 activation and protects cardiac myocytes from ischemia/reperfusion‐induced apoptosis PA Townsend, TM Scarabelli, E Pasini, G Gitti, M Menegazzi, H Suzuki, ... The FASEB journal 18 (13), 1621-1623, 2004 | 249 | 2004 |
Robust, universal biomarker assay to detect senescent cells in biological specimens K Evangelou, N Lougiakis, SV Rizou, A Kotsinas, D Kletsas, ... Aging cell 16 (1), 192-197, 2017 | 222 | 2017 |
BAG-1: a multifunctional regulator of cell growth and survival PA Townsend, RI Cutress, A Sharp, M Brimmell, G Packham Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1603 (2), 83-98, 2003 | 210 | 2003 |
Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO TM Scarabelli, A Stephanou, E Pasini, G Gitti, P Townsend, K Lawrence, ... Journal of the American College of Cardiology 43 (5), 865-874, 2004 | 198 | 2004 |
A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells E Miranda, IK Nordgren, AL Male, CE Lawrence, F Hoakwie, F Cuda, ... Journal of the American Chemical Society 135 (28), 10418-10425, 2013 | 196 | 2013 |
Role of the JAK–STAT pathway in myocardial injury SP Barry, PA Townsend, DS Latchman, A Stephanou Trends in molecular medicine 13 (2), 82-89, 2007 | 195 | 2007 |
A deep learning framework for predicting response to therapy in cancer T Sakellaropoulos, K Vougas, S Narang, F Koinis, A Kotsinas, A Polyzos, ... Cell reports 29 (11), 3367-3373. e4, 2019 | 179 | 2019 |
Clinical implications of apoptosis in ischemic myocardium TM Scarabelli, R Knight, A Stephanou, P Townsend, C Chen-Scarabelli, ... Current problems in cardiology 31 (3), 181-264, 2006 | 158 | 2006 |
Identification of markers of prostate cancer progression using candidate gene expression SET Larkin, S Holmes, IA Cree, T Walker, V Basketter, B Bickers, S Harris, ... British journal of cancer 106 (1), 157-165, 2012 | 147 | 2012 |
The DNA damage response and immune signaling alliance: Is it good or bad? Nature decides when and where IS Pateras, S Havaki, X Nikitopoulou, K Vougas, PA Townsend, ... Pharmacology & therapeutics 154, 36-56, 2015 | 144 | 2015 |
Large-scale transcriptome-wide association study identifies new prostate cancer risk regions N Mancuso, S Gayther, A Gusev, W Zheng, KL Penney, Z Kote-Jarai, ... Nature communications 9 (1), 4079, 2018 | 143 | 2018 |
BAG-1: a multi-functional pro-survival molecule PA Townsend, A Stephanou, G Packham, DS Latchman The international journal of biochemistry & cell biology 37 (2), 251-259, 2005 | 125 | 2005 |
Shared heritability and functional enrichment across six solid cancers X Jiang, HK Finucane, FR Schumacher, SL Schmit, JP Tyrer, Y Han, ... Nature communications 10 (1), 431, 2019 | 121 | 2019 |