Lipid metabolism reprogramming and its potential targets in cancer C Cheng, F Geng, X Cheng, D Guo Cancer communications 38, 1-14, 2018 | 616 | 2018 |
Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1–mediated lipogenesis F Geng, X Cheng, X Wu, JY Yoo, C Cheng, JY Guo, X Mo, P Ru, B Hurwitz, ... Clinical Cancer Research 22 (21), 5337-5348, 2016 | 277 | 2016 |
Glucose-mediated N-glycosylation of SCAP is essential for SREBP-1 activation and tumor growth C Cheng, P Ru, F Geng, J Liu, JY Yoo, X Wu, X Cheng, V Euthine, P Hu, ... Cancer cell 28 (5), 569-581, 2015 | 256 | 2015 |
Targeting DGAT1 ameliorates glioblastoma by increasing fat catabolism and oxidative stress X Cheng, F Geng, M Pan, X Wu, Y Zhong, C Wang, Z Tian, C Cheng, ... Cell metabolism 32 (2), 229-242. e8, 2020 | 199 | 2020 |
SCAP/SREBPs are central players in lipid metabolism and novel metabolic targets in cancer therapy X Cheng, J Li, D Guo Current topics in medicinal chemistry 18 (6), 484-493, 2018 | 120 | 2018 |
Porcine induced pluripotent stem cells require LIF and maintain their developmental potential in early stage of embryos D Cheng, Y Guo, Z Li, Y Liu, X Gao, Y Gao, X Cheng, J Hu, H Wang PloS one 7 (12), e51778, 2012 | 91 | 2012 |
Feedback loop regulation of SCAP/SREBP-1 by miR-29 modulates EGFR signaling-driven glioblastoma growth P Ru, P Hu, F Geng, X Mo, C Cheng, JY Yoo, X Cheng, X Wu, JY Guo, ... Cell reports 16 (6), 1527-1535, 2016 | 87 | 2016 |
Lipid droplets maintain energy homeostasis and glioblastoma growth via autophagic release of stored fatty acids X Wu, F Geng, X Cheng, Q Guo, Y Zhong, TF Cloughesy, WH Yong, ... Iscience 23 (10), 2020 | 73 | 2020 |
Robust activation of the human but not mouse telomerase gene during the induction of pluripotency R Mathew, W Jia, A Sharma, Y Zhao, LE Clarke, X Cheng, H Wang, ... The FASEB Journal 24 (8), 2702, 2010 | 68 | 2010 |
Surgery-mediated tumor-promoting effects on the immune microenvironment X Cheng, H Zhang, A Hamad, H Huang, A Tsung Seminars in cancer biology 86, 408-419, 2022 | 46 | 2022 |
Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumour growth C Cheng, F Geng, Z Li, Y Zhong, H Wang, X Cheng, Y Zhao, X Mo, ... Nature metabolism 4 (5), 575-588, 2022 | 42 | 2022 |
BMP15 Gene Is Activated During Human Amniotic Fluid Stem Cell Differentiation into Oocyte-Like Cells X Cheng, S Chen, X Yu, P Zheng, H Wang DNA and Cell Biology 31 (7), 1198-1204, 2012 | 42 | 2012 |
Neutrophils extracellular traps inhibition improves PD-1 blockade immunotherapy in colorectal cancer H Zhang, Y Wang, A Onuma, J He, H Wang, Y Xia, R Lal, X Cheng, ... Cancers 13 (21), 5333, 2021 | 41 | 2021 |
Characterization of the putative phosphorylation sites of the AQP2 c-terminus and their role in AQP2 trafficking in LLC-PK1 cells. J Arthur*, J Huang*, N Nomura, WW Jin, W Li, X Cheng, D Brown, HJ Lu. Am J Physiol Renal Physiol, 2015 | 36 | 2015 |
Translationally controlled tumor protein (TCTP) downregulates Oct4 expression in mouse pluripotent cells X Cheng, J Li, J Deng, L ZhenZhen, SY Meng, W Huayan Biochemistry and Molecular Biology Reports 45 (1), 20-25, 2012 | 19 | 2012 |
Analysis of SCAP N-glycosylation and Trafficking in Human Cells C Cheng, JY Guo, F Geng, X Wu, X Cheng, Q Li, D Guo Journal of Visualized Experiments: Jove, 2016 | 16 | 2016 |
DGAT1 protects tumor from lipotoxicity, emerging as a promising metabolic target for cancer therapy X Cheng, F Geng, D Guo Molecular & Cellular Oncology 7 (6), 1805257, 2020 | 15 | 2020 |
Differentiation of human amniotic fluid stem cells into cardiomyocytes through embryonic body formation H Wang, S Chen, X Cheng, Z Dou Sheng wu gong cheng xue bao= Chinese journal of biotechnology 24 (9), 1582-1587, 2008 | 11 | 2008 |
Multiple targeting motifs direct NRAMP1 into lysosomes X Cheng, H Wang Biochemical and biophysical research communications 419 (3), 578-583, 2012 | 8 | 2012 |
Functional analysis of bovine Nramp1 and production of transgenic cloned embryos in vitro X Cheng, X Yu, Y Liu, J Deng, X Ma, H Wang Zygote 23 (1), 83-92, 2015 | 6 | 2015 |