Antidepressant-like effects of fractions, essential oil, carnosol and betulinic acid isolated from Rosmarinus officinalis L. DG Machado, MP Cunha, VB Neis, GO Balen, A Colla, LEB Bettio, ... Food Chemistry 136 (2), 999-1005, 2013 | 165 | 2013 |
Creatine, similar to ketamine, counteracts depressive-like behavior induced by corticosterone via PI3K/Akt/mTOR pathway FL Pazini, MP Cunha, JM Rosa, ARS Colla, V Lieberknecht, Á Oliveira, ... Molecular neurobiology 53, 6818-6834, 2016 | 131 | 2016 |
Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide–cGMP and PI3K/mTOR pathways LEB Bettio, MP Cunha, J Budni, FL Pazini, Á Oliveira, AR Colla, ... Behavioural brain research 234 (2), 137-148, 2012 | 97 | 2012 |
Central irisin administration affords antidepressant-like effect and modulates neuroplasticity-related genes in the hippocampus and prefrontal cortex of mice A Siteneski, MP Cunha, V Lieberknecht, FL Pazini, K Gruhn, PS Brocardo, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 84, 294-303, 2018 | 77 | 2018 |
Involvement of PI3K/Akt signaling pathway and its downstream intracellular targets in the antidepressant-like effect of creatine MP Cunha, J Budni, FK Ludka, FL Pazini, JM Rosa, Á Oliveira, MW Lopes, ... Molecular neurobiology 53, 2954-2968, 2016 | 64 | 2016 |
Serotonergic and noradrenergic systems are implicated in the antidepressant-like effect of ursolic acid in mice ARS Colla, A Oliveira, FL Pazini, JM Rosa, LM Manosso, MP Cunha, ... Pharmacology Biochemistry and Behavior 124, 108-116, 2014 | 57 | 2014 |
Therapeutic potential of ursolic acid to manage neurodegenerative and psychiatric diseases AB Ramos-Hryb, FL Pazini, MP Kaster, ALS Rodrigues Cns Drugs 31 (12), 1029-1041, 2017 | 52 | 2017 |
The antidepressant-like effect of physical activity on a voluntary running wheel MP Cunha, A Oliveira, FL Pazini, DG Machado, LE Bettio, J Budni, ... Med Sci Sports Exerc 45 (5), 851-859, 2013 | 52 | 2013 |
The modulation of NMDA receptors and l-arginine/nitric oxide pathway is implicated in the anti-immobility effect of creatine in the tail suspension test MP Cunha, FL Pazini, FK Ludka, JM Rosa, Á Oliveira, J Budni, ... Amino acids 47, 795-811, 2015 | 46 | 2015 |
The antidepressant‐like effect of chronic guanosine treatment is associated with increased hippocampal neuronal differentiation LEB Bettio, VB Neis, FL Pazini, PS Brocardo, AR Patten, J Gil‐Mohapel, ... European Journal of Neuroscience 43 (8), 1006-1015, 2016 | 45 | 2016 |
Evidence for the involvement of 5-HT1A receptor in the acute antidepressant-like effect of creatine in mice MP Cunha, FL Pazini, Á Oliveira, DG Machado, ALS Rodrigues Brain Research Bulletin 95, 61-69, 2013 | 41 | 2013 |
Creatine prevents corticosterone-induced reduction in hippocampal proliferation and differentiation: possible implication for its antidepressant effect FL Pazini, MP Cunha, D Azevedo, JM Rosa, A Colla, J de Oliveira, ... Molecular neurobiology 54, 6245-6260, 2017 | 40 | 2017 |
Augmentation effect of ketamine by guanosine in the novelty-suppressed feeding test is dependent on mTOR signaling pathway A Camargo, FL Pazini, JM Rosa, IAV Wolin, M Moretti, PB Rosa, VB Neis, ... Journal of psychiatric research 115, 103-112, 2019 | 39 | 2019 |
Creatine, similarly to ketamine, affords antidepressant-like effects in the tail suspension test via adenosine A1 and A2A receptor activation MP Cunha, FL Pazini, JM Rosa, AB Ramos-Hryb, Á Oliveira, MP Kaster, ... Purinergic Signalling 11, 215-227, 2015 | 39 | 2015 |
MPP+-Lesioned Mice: an Experimental Model of Motor, Emotional, Memory/Learning, and Striatal Neurochemical Dysfunctions MP Cunha, FL Pazini, V Lieberknecht, J Budni, Á Oliveira, JM Rosa, ... Molecular neurobiology 54, 6356-6377, 2017 | 38 | 2017 |
The activation of α1-adrenoceptors is implicated in the antidepressant-like effect of creatine in the tail suspension test MP Cunha, FL Pazini, Á Oliveira, LEB Bettio, JM Rosa, DG Machado, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 44, 39-50, 2013 | 37 | 2013 |
The possible beneficial effects of creatine for the management of depression FL Pazini, MP Cunha, ALS Rodrigues Progress in Neuro-Psychopharmacology and Biological Psychiatry 89, 193-206, 2019 | 36 | 2019 |
Antidepressant-like and pro-neurogenic effects of physical exercise: the putative role of FNDC5/irisin pathway A Siteneski, G Olescowicz, FL Pazini, A Camargo, DB Fraga, PS Brocardo, ... Journal of neural transmission 127, 355-370, 2020 | 35 | 2020 |
Ascorbic acid presents rapid behavioral and hippocampal synaptic plasticity effects DB Fraga, AP Costa, G Olescowicz, A Camargo, FL Pazini, AE Freitas, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 96, 109757, 2020 | 30 | 2020 |
Involvement of PKA, PKC, CAMK-II and MEK1/2 in the acute antidepressant-like effect of creatine in mice MP Cunha, J Budni, FL Pazini, A Oliveira, JM Rosa, MW Lopes, RB Leal, ... Pharmacological Reports 66, 653-659, 2014 | 25 | 2014 |