| Nicotinamide pathway-dependent Sirt1 activation restores calcium homeostasis to achieve neuroprotection in spinocerebellar ataxia type 7 CA Stoyas, DD Bushart, PM Switonski, JM Ward, A Alaghatta, M Tang, ... Neuron 105 (4), 630-644. e9, 2020 | 78 | 2020 |
| Ion channel dysfunction in cerebellar ataxia DD Bushart, VG Shakkottai Neuroscience letters 688, 41-48, 2019 | 72 | 2019 |
| Targeting potassium channels to treat cerebellar ataxia DD Bushart, R Chopra, V Singh, GG Murphy, H Wulff, VG Shakkottai Annals of clinical and translational neurology 5 (3), 297-314, 2018 | 68 | 2018 |
| Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease DD Bushart, GG Murphy, VG Shakkottai Annals of Translational Medicine 4 (2), 2016 | 45 | 2016 |
| Antisense oligonucleotide therapy rescues aggresome formation in a novel spinocerebellar ataxia type 3 human embryonic stem cell line LR Moore, L Keller, DD Bushart, RG Delatorre, D Li, HS McLoughlin, ... Stem cell research 39, 101504, 2019 | 36 | 2019 |
| A Chlorzoxazone‐Baclofen Combination Improves Cerebellar Impairment in Spinocerebellar Ataxia Type 1 DD Bushart, H Huang, LJ Man, LM Morrison, VG Shakkottai Movement Disorders 36 (3), 622-631, 2021 | 33 | 2021 |
| Dendritic potassium channel dysfunction may contribute to dendrite degeneration in spinocerebellar ataxia type 1 R Chopra, DD Bushart, VG Shakkottai PLoS One 13 (5), e0198040, 2018 | 31 | 2018 |
| Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1 R Chopra, DD Bushart, JP Cooper, D Yellajoshyula, LM Morrison, ... Human molecular genetics 29 (19), 3249-3265, 2020 | 30 | 2020 |
| Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann–Pick diseases ML Schultz, MV Fawaz, RD Azaria, TC Hollon, EA Liu, TJ Kunkel, ... BMC medicine 17, 1-18, 2019 | 22 | 2019 |
| Antisense Oligonucleotide Therapy Targeted Against ATXN3 Improves Potassium Channel–Mediated Purkinje Neuron Dysfunction in Spinocerebellar Ataxia Type 3 DD Bushart, AJ Zalon, H Zhang, LM Morrison, Y Guan, HL Paulson, ... The Cerebellum 20, 41-53, 2021 | 21 | 2021 |
| Compartmentalized actions of the plasminogen activator inhibitors, PAI-1 and NSP, in ischemic stroke D Torrente, EJ Su, L Fredriksson, M Warnock, D Bushart, KM Mann, ... Translational stroke research 13 (5), 801-815, 2022 | 16 | 2022 |
| Vulnerability of human cerebellar neurons to degeneration in ataxia-causing channelopathies DD Bushart, VG Shakkottai Frontiers in Systems Neuroscience 16, 908569, 2022 | 6 | 2022 |
| Preliminary study of vibrotactile feedback during home-based balance and coordination training in individuals with cerebellar ataxia S Jabri, DD Bushart, C Kinnaird, T Bao, A Bu, VG Shakkottai, KH Sienko Sensors 22 (9), 3512, 2022 | 6 | 2022 |
| Increased dendritic excitability and calcium-dependent PKC activation: a novel mechanism underlying Purkinje neuron dendritic degeneration in cerebellar ataxias R Chopra, AG Wasserman, DD Bushart, JM Dell'Orco, VG Shakkottai ANNALS OF NEUROLOGY 80, S33-S34, 2016 | 4 | 2016 |
| Therapeutic combination for treatment of cerebellar ataxia V Shakkottai, D Bushart US Patent 11,382,897, 2022 | 1 | 2022 |
| Increased intrinsic membrane excitability is associated with olivary hypertrophy in spinocerebellar ataxia type 1 LM Morrison, H Huang, HP Handler, M Fu, DM Jones, DD Bushart, ... Human Molecular Genetics 33 (24), 2159-2176, 2024 | | 2024 |
| Increased intrinsic membrane excitability is associated with hypertrophic olivary degeneration in spinocerebellar ataxia type 1 LM Morrison, H Huang, HP Handler, M Fu, DD Bushart, SS Pappas, ... bioRxiv, 2023 | | 2023 |
| Augmenting BK Channel Function as Therapy for Spinocerebellar Ataxia (SCA)(5571) S Srinivasan, D Bushart, V Shakkottai Neurology 94 (15_supplement), 5571, 2020 | | 2020 |
| Regional Differences in Purkinje Neuron Degeneration Reveal a Region-Specific Dysregulated Ion Channel Module in Spinocerebellar Ataxia Type 1 R Chopra, DD Bushart, JP Cooper, D Yellajoshyula, H Huang, ... ANNALS OF NEUROLOGY 86, S85-S85, 2019 | | 2019 |
| The Contribution of Calcium-Activated Potassium Channel Dysfunction to Altered Purkinje Neuron Membrane Excitability in Spinocerebellar Ataxia D Bushart | | 2018 |
