Genetic drivers of epigenetic and transcriptional variation in human immune cells L Chen, B Ge, FP Casale, L Vasquez, T Kwan, D Garrido-Martín, S Watt, ... Cell 167 (5), 1398-1414. e24, 2016 | 673 | 2016 |
Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture HF Zheng, V Forgetta, YH Hsu, K Estrada, A Rosello‐Diez, PJ Leo, ... Nature 526 (7571), 112-117, 2015 | 550 | 2015 |
Identification of novel antibacterial peptides by chemoinformatics and machine learning CD Fjell, H Jenssen, K Hilpert, WA Cheung, N Panté, REW Hancock, ... Journal of medicinal chemistry 52 (7), 2006-2015, 2009 | 333 | 2009 |
Single-cell analysis of human adipose tissue identifies depot-and disease-specific cell types J Vijay, MF Gauthier, RL Biswell, DA Louiselle, JJ Johnston, WA Cheung, ... Nature metabolism 2 (1), 97-109, 2020 | 324 | 2020 |
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis AS Harutyunyan, B Krug, H Chen, S Papillon-Cavanagh, M Zeinieh, ... Nature communications 10 (1), 1262, 2019 | 277 | 2019 |
n-SIFT: n-dimensional scale invariant feature transform W Cheung, G Hamarneh IEEE Transactions on Image Processing 18 (9), 2012-2021, 2009 | 198 | 2009 |
N-sift: N-dimensional scale invariant feature transform for matching medical images W Cheung, G Hamarneh 2007 4th IEEE international symposium on biomedical imaging: from nano to …, 2007 | 179 | 2007 |
Increased DNA methylation variability in type 1 diabetes across three immune effector cell types DS Paul, AE Teschendorff, MAN Dang, R Lowe, MI Hawa, S Ecker, ... Nature communications 7 (1), 13555, 2016 | 160 | 2016 |
The transcription factor encyclopedia D Yusuf, SL Butland, MI Swanson, E Bolotin, A Ticoll, WA Cheung, ... Genome biology 13, 1-25, 2012 | 134 | 2012 |
Optimization of antibacterial peptides by genetic algorithms and cheminformatics CD Fjell, H Jenssen, WA Cheung, REW Hancock, A Cherkasov Chemical biology & drug design 77 (1), 48-56, 2011 | 118 | 2011 |
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types S Ecker, L Chen, V Pancaldi, FO Bagger, JM Fernández, ... Genome biology 18, 1-17, 2017 | 117 | 2017 |
Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome WA Cheung, X Shao, A Morin, V Siroux, T Kwan, B Ge, D Aïssi, L Chen, ... Genome biology 18, 1-21, 2017 | 93 | 2017 |
Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation S Busche, X Shao, M Caron, T Kwan, F Allum, WA Cheung, B Ge, ... Genome biology 16, 1-18, 2015 | 93 | 2015 |
Genomic answers for children: Dynamic analyses of> 1000 pediatric rare disease genomes ASA Cohen, EG Farrow, AT Abdelmoity, JT Alaimo, SM Amudhavalli, ... Genetics in Medicine 24 (6), 1336-1348, 2022 | 58 | 2022 |
Mutations in THAP11 cause an inborn error of cobalamin metabolism and developmental abnormalities AM Quintana, HC Yu, A Brebner, M Pupavac, EA Geiger, A Watson, ... Human molecular genetics 26 (15), 2838-2849, 2017 | 57 | 2017 |
Epigenome data release: a participant-centered approach to privacy protection SOM Dyke, WA Cheung, Y Joly, O Ammerpohl, P Lutsik, MA Rothstein, ... Genome biology 16, 1-12, 2015 | 45 | 2015 |
High-resolution analyses of human sperm dynamic methylome reveal thousands of novel age-related epigenetic alterations M Cao, X Shao, P Chan, W Cheung, T Kwan, T Pastinen, B Robaire Clinical epigenetics 12, 1-16, 2020 | 41 | 2020 |
Inborn Error of Cobalamin Metabolism Associated with the Intracellular Accumulation of Transcobalamin‐Bound Cobalamin and Mutations in ZNF143, Which … M Pupavac, D Watkins, F Petrella, S Fahiminiya, A Janer, W Cheung, ... Human mutation 37 (9), 976-982, 2016 | 38 | 2016 |
Quantitative biomedical annotation using medical subject heading over-representation profiles (MeSHOPs) WA Cheung, BFF Ouellette, WW Wasserman BMC bioinformatics 13, 1-12, 2012 | 35 | 2012 |
Inferring novel gene-disease associations using medical subject heading over-representation profiles WA Cheung, BFF Ouellette, WW Wasserman Genome Medicine 4, 75, 2012 | 29 | 2012 |