Hepcidin antagonists for potential treatments of disorders with hepcidin excess M Poli, M Asperti, P Ruzzenenti, M Regoni, P Arosio Frontiers in pharmacology 5, 86, 2014 | 152 | 2014 |
NCOA4-mediated ferritinophagy promotes ferroptosis induced by erastin, but not by RSL3 in HeLa cells M Gryzik, M Asperti, A Denardo, P Arosio, M Poli Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1868 (2), 118913, 2021 | 101 | 2021 |
Glycol-split nonanticoagulant heparins are inhibitors of hepcidin expression in vitro and in vivo M Poli, M Asperti, A Naggi, N Campostrini, D Girelli, M Corbella, M Benzi, ... Blood, The Journal of the American Society of Hematology 123 (10), 1564-1573, 2014 | 80 | 2014 |
Cell growth potential drives ferroptosis susceptibility in rhabdomyosarcoma and myoblast cell lines S Codenotti, M Poli, M Asperti, D Zizioli, F Marampon, A Fanzani Journal of cancer research and clinical oncology 144, 1717-1730, 2018 | 64 | 2018 |
Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity F Maccarinelli, E Gammella, M Asperti, M Regoni, G Biasiotto, E Turco, ... Journal of Molecular Medicine 92, 859-869, 2014 | 55 | 2014 |
H-ferritin suppression and pronounced mitochondrial respiration make Hepatocellular Carcinoma cells sensitive to RSL3-induced ferroptosis M Asperti, S Bellini, E Grillo, M Gryzik, L Cantamessa, R Ronca, ... Free Radical Biology and Medicine 169, 294-303, 2021 | 44 | 2021 |
Oversulfated heparins with low anticoagulant activity are strong and fast inhibitors of hepcidin expression in vitro and in vivo M Poli, M Asperti, P Ruzzenenti, L Mandelli, N Campostrini, G Martini, ... Biochemical Pharmacology 92 (3), 467-475, 2014 | 42 | 2014 |
Sucrosomial® Iron Supplementation in Mice: Effects on Blood Parameters, Hepcidin, and Inflammation M Asperti, M Gryzik, E Brilli, A Castagna, M Corbella, R Gottardo, D Girelli, ... Nutrients 10 (10), 1349, 2018 | 39 | 2018 |
High sulfation and a high molecular weight are important for anti-hepcidin activity of heparin M Asperti, A Naggi, E Esposito, P Ruzzenenti, M Di Somma, M Gryzik, ... Frontiers in pharmacology 6, 316, 2016 | 26 | 2016 |
Caveolin-1 promotes radioresistance in rhabdomyosarcoma through increased oxidative stress protection and DNA repair S Codenotti, F Marampon, L Triggiani, ML Bonù, SM Magrini, P Ceccaroli, ... Cancer Letters 505, 1-12, 2021 | 25 | 2021 |
Non-anticoagulant heparins are hepcidin antagonists for the treatment of anemia M Poli, M Asperti, P Ruzzenenti, A Naggi, P Arosio Molecules 22 (4), 598, 2017 | 25 | 2017 |
The Ferritin-Heavy-Polypeptide-Like-17 (FTHL17) gene encodes a ferritin with low stability and no ferroxidase activity and with a partial nuclear localization P Ruzzenenti, M Asperti, S Mitola, E Crescini, F Maccarinelli, M Gryzik, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (6), 1267-1273, 2015 | 21 | 2015 |
Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice M Poli, F Anower-E-Khuda, M Asperti, P Ruzzenenti, M Gryzik, A Denardo, ... Journal of Biological Chemistry 294 (36), 13292-13303, 2019 | 19 | 2019 |
Pentosan polysulfate to control hepcidin expression in vitro and in vivo M Asperti, A Denardo, M Gryzik, A Castagna, D Girelli, A Naggi, P Arosio, ... Biochemical pharmacology 175, 113867, 2020 | 17 | 2020 |
Heparanase overexpression reduces hepcidin expression, affects iron homeostasis and alters the response to inflammation M Asperti, T Stuemler, M Poli, M Gryzik, L Lifshitz, EG Meyron-Holtz, ... PloS one 11 (10), e0164183, 2016 | 17 | 2016 |
BMP6 binding to heparin and heparan sulfate is mediated by N-terminal and C-terminal clustered basic residues A Denardo, S Elli, S Federici, M Asperti, M Gryzik, P Ruzzenenti, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (2), 129799, 2021 | 16 | 2021 |
The role of heparin, heparanase and heparan sulfates in hepcidin regulation M Asperti, A Denardo, M Gryzik, P Arosio, M Poli Vitamins and hormones 110, 157-188, 2019 | 14 | 2019 |
The antitumor didox acts as an iron chelator in hepatocellular carcinoma cells M Asperti, L Cantamessa, S Ghidinelli, M Gryzik, A Denardo, A Giacomini, ... Pharmaceuticals 12 (3), 129, 2019 | 11 | 2019 |
Iron supplementation enhances RSL3-induced ferroptosis to treat naïve and prevent castration-resistant prostate cancer F Maccarinelli, D Coltrini, S Mussi, M Bugatti, M Turati, P Chiodelli, ... Cell Death Discovery 9 (1), 81, 2023 | 8 | 2023 |
Production and characterization of functional recombinant hybrid heteropolymers of camel hepcidin and human ferritin H and L chains M Boumaiza, F Carmona, M Poli, M Asperti, A Gianoncelli, M Bertuzzi, ... Protein Engineering, Design and Selection 30 (2), 77-84, 2017 | 8 | 2017 |