Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Management Group Liefer Laura A. 51 Wetterstrand Kris A. 51 Good Peter J. 51 ... nature 447 (7146), 799-816, 2007 | 5992 | 2007 |
Structure‐based design of a T‐cell receptor leads to nearly 100‐fold improvement in binding affinity for pepMHC JN Haidar, B Pierce, Y Yu, W Tong, M Li, Z Weng Proteins: Structure, Function, and Bioinformatics 74 (4), 948-960, 2009 | 103 | 2009 |
Somatostatin receptor-specific analogs: effects on cell proliferation and growth hormone secretion in human somatotroph tumors DC Danila, JNS Haidar, X Zhang, L Katznelson, MD Culler, A Klibanski The Journal of Clinical Endocrinology & Metabolism 86 (7), 2976-2981, 2001 | 89 | 2001 |
Molecular basis for necitumumab inhibition of EGFR variants associated with acquired cetuximab resistance A Bagchi, JN Haidar, SW Eastman, M Vieth, M Topper, MD Iacolina, ... Molecular cancer therapeutics 17 (2), 521-531, 2018 | 51 | 2018 |
A universal combinatorial design of antibody framework to graft distinct CDR sequences: A bioinformatics approach JN Haidar, QA Yuan, L Zeng, M Snavely, X Luna, H Zhang, W Zhu, ... Proteins: Structure, Function, and Bioinformatics 80 (3), 896-912, 2012 | 47 | 2012 |
Bispecific targeting of PD-1 and PD-L1 enhances T-cell activation and antitumor immunity H Kotanides, Y Li, M Malabunga, C Carpenito, SW Eastman, Y Shen, ... Cancer Immunology Research 8 (10), 1300-1310, 2020 | 46 | 2020 |
Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054 Y Li, C Carpenito, G Wang, D Surguladze, A Forest, M Malabunga, ... Journal for immunotherapy of cancer 6, 1-14, 2018 | 35 | 2018 |
Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen A Poole, V Karuppiah, A Hartt, JN Haidar, S Moureau, T Dobrzycki, ... Nature communications 13 (1), 5333, 2022 | 34 | 2022 |
Overexpression of wild-type activin receptor alk4-1 restores activin antiproliferative effects in human pituitary tumor cells DC Danila, X Zhang, Y Zhou, JNS Haidar, A Klibanski The Journal of Clinical Endocrinology & Metabolism 87 (10), 4741-4746, 2002 | 30 | 2002 |
Comparison of predicted extinction coefficients of monoclonal antibodies with experimental values as measured by the Edelhoch method H Maity, A Wei, E Chen, JN Haidar, A Srivastava, J Goldstein International journal of biological macromolecules 77, 260-265, 2015 | 26 | 2015 |
Combinations of affinity-enhancing mutations in a T cell receptor reveal highly nonadditive effects within and between complementarity determining regions and chains BG Pierce, JN Haidar, Y Yu, Z Weng Biochemistry 49 (33), 7050-7059, 2010 | 24 | 2010 |
Backbone flexibility of CDR3 and immune recognition of antigens JN Haidar, W Zhu, J Lypowy, BG Pierce, A Bari, K Persaud, X Luna, ... Journal of molecular biology 426 (7), 1583-1599, 2014 | 19 | 2014 |
Characterization of 7A5: a human CD137 (4-1BB) receptor binding monoclonal antibody with differential agonist properties that promotes antitumor immunity H Kotanides, RM Sattler, MB Lebron, C Carpenito, J Shen, J Li, ... Molecular Cancer Therapeutics 19 (4), 988-998, 2020 | 15 | 2020 |
The molecular basis of blocking the TIM-3 checkpoint with the LY3321367 mAb in cancer immunotherapy JN Haidar, S Antonysamy, S Mathew, L Wu, Y Zhang, MC Kearins, L Shen, ... Cancer Research 79 (13_Supplement), 2753-2753, 2019 | 8 | 2019 |
882 Selective affinity-enhanced T cell receptor bispecific targeting of KRAS G12D neoantigen driven cancers A Whale, A Poole, V Karuppiah, A Hartt, J Haidar, S Moureau, AB Lin, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A924-A924, 2021 | 1 | 2021 |
Cd200 receptor antagonist binding molecules KM Bell-mcguinn, SJ Demarest, KE Driscoll, RB Holmgaard, AM Russell, ... US Patent App. 17/774,214, 2022 | | 2022 |
Characterization of a human CD137 (4-1BB) receptor binding monoclonal antibody with differential agonist properties that promotes antitumor immunity H Kotanides, RM Sattler, M Lebron, C Carpenito, J Shen, J Li, ... JOURNAL FOR IMMUNOTHERAPY OF CANCER 7, 2019 | | 2019 |
Preclinical characterization of the anti-PD-L1 monoclonal antibody LY3300054 C Carpenito, Y Li, GX Wang, MS Malabunga, JN Haidar, A Forest, ... Cancer Research 78 (13_Supplement), 2730-2730, 2018 | | 2018 |
A universal combinatorial design of antibody framework to graft distinct CDR sequences: A bioinformatics approach JN Haidar, QA Yuan, L Zeng, M Snavely, X Luna, H Zhang, W Zhu, ... Proteins: Structure, Function, and Bioinformatics 81 (9), 1677-1677, 2013 | | 2013 |
A universal combinatorial design of antibody framework to graft distinct CDR sequences: A bioinformatics approach (vol 80, pg 896, 2012) JN Haidar, QA Yuan, L Zeng, M Snavely, X Luna, H Zhang, W Zhu, ... PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 81 (9), 1677-1677, 2013 | | 2013 |