Quantitative mass spectrometry-based multiplexing compares the abundance of 5000 S. cerevisiae proteins across 10 carbon sources JA Paulo, JD O'Connell, RA Everley, J O'Brien, MA Gygi, SP Gygi Journal of proteomics 148, 85-93, 2016 | 197 | 2016 |
eIF2B activator prevents neurological defects caused by a chronic integrated stress response YL Wong, L LeBon, AM Basso, KL Kohlhaas, AL Nikkel, HM Robb, ... Elife 8, e42940, 2019 | 175 | 2019 |
Proteome-wide evaluation of two common protein quantification methods JD O’Connell, JA Paulo, JJ O’Brien, SP Gygi Journal of proteome research 17 (5), 1934-1942, 2018 | 174 | 2018 |
Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance MF Pech, LE Fong, JE Villalta, LJG Chan, S Kharbanda, JJ O'Brien, ... Elife 8, e47362, 2019 | 80 | 2019 |
Compositional proteomics: effects of spatial constraints on protein quantification utilizing isobaric tags JJ O’Brien, JD O’Connell, JA Paulo, S Thakurta, CM Rose, MP Weekes, ... Journal of proteome research 17 (1), 590-599, 2018 | 56 | 2018 |
Novel insights from a multiomics dissection of the Hayflick limit M Chan, H Yuan, I Soifer, TM Maile, RY Wang, A Ireland, JJ O'Brien, ... Elife 11, e70283, 2022 | 51 | 2022 |
The effects of nonignorable missing data on label-free mass spectrometry proteomics experiments JJ O'Brien, HP Gunawardena, JA Paulo, X Chen, JG Ibrahim, SP Gygi, ... The annals of applied statistics 12 (4), 2075, 2018 | 50 | 2018 |
Automated 16-plex plasma proteomics with real-time search and ion mobility mass spectrometry enables large-scale profiling in naked mole-rats and mice A Gaun, KN Lewis Hardell, N Olsson, JJ O’Brien, S Gollapudi, M Smith, ... Journal of Proteome Research 20 (2), 1280-1295, 2021 | 36 | 2021 |
Improved method for determining absolute phosphorylation stoichiometry using bayesian statistics and isobaric labeling MY Lim, J O’Brien, JA Paulo, SP Gygi Journal of proteome research 16 (11), 4217-4226, 2017 | 30 | 2017 |
Racial differences in diffusion of intensity-modulated radiation therapy for localized prostate cancer EK Cobran, RC Chen, R Overman, AM Meyer, TM Kuo, J O’Brien, ... American journal of men's health 10 (5), 399-407, 2016 | 19 | 2016 |
Comprehensive coagulation profiling at the point-of-care using a novel laser-based approach SK Nadkarni Seminars in thrombosis and hemostasis 45 (03), 264-274, 2019 | 17 | 2019 |
Peptide-spectra matching from weak supervision SS Schoenholz, S Hackett, L Deming, E Melamud, N Jaitly, F McAllister, ... arXiv preprint arXiv:1808.06576, 2018 | 10 | 2018 |
Results of a Phase II Trial of Carboplatin, Pemetrexed, and Bevacizumab for the Treatment of Never or Former/Light Smoking Patients With Stage IV Non–Small Cell Lung Cancer JM Weiss, LC Villaruz, J O'Brien, A Ivanova, C Lee, JG Olson, G Pollack, ... Clinical lung cancer 17 (2), 128-132, 2016 | 10 | 2016 |
Precise estimation of in vivo protein turnover rates JJ O’Brien, V Narayan, Y Wong, P Seitzer, CM Sandoval, N Haste, ... bioRxiv, 2020.11. 10.377440, 2020 | 7 | 2020 |
Accelerating high-dimensional clustering with lossless data reduction BF Qaqish, JJ O’Brien, JC Hibbard, KJ Clowers Bioinformatics 33 (18), 2867-2872, 2017 | 7 | 2017 |
QuantFusion: novel unified methodology for enhanced coverage and precision in quantifying global proteomic changes in whole tissues HP Gunawardena, J O'Brien, JA Wrobel, L Xie, SR Davies, S Li, MJ Ellis, ... Molecular & Cellular Proteomics 15 (2), 740-751, 2016 | 7 | 2016 |
Insights into the molecular basis of genome stability and pristine proteostasis in naked mole-rats V Narayan, M McMahon, JJ O’Brien, F McAllister, R Buffenstein The Extraordinary Biology of the Naked Mole-Rat, 287-314, 2021 | 6 | 2021 |
Conditional Fragment Ion Probabilities Improve Database Searching for Nonmonoisotopic Precursors JJ O’Brien, M Gadzuk-Shea, PM Seitzer, R Rad, FE McAllister, ... Journal of Proteome Research 22 (2), 334-342, 2022 | 4 | 2022 |
A data analysis framework for combining multiple batches increases the power of isobaric proteomics experiments JJ O’Brien, A Raj, A Gaun, A Waite, W Li, DG Hendrickson, N Olsson, ... Nature Methods 21 (2), 290-300, 2024 | 3 | 2024 |
Triple‐threat quantitative multiplexed plasma proteomics analysis on immune complex disease MRL‐lpr mice A Gaun, M Preciado López, N Olsson, JCK Wang, LJG Chan, J O'Brien, ... Proteomics 22 (19-20), 2100242, 2022 | 3 | 2022 |